Crede hit reliever Chad Qualls' first pitch for a game-tying grand slam in the seventh, and Alex Cintron delivered a game-winning bases-loaded single in the 10th Saturday as the White Sox beat the Astros 6-5.
Eight months ago on the same field, Paul Konerko drove Qualls' first pitch for a grand slam in Game 2 of the World Series, and the White Sox went on to a sweep and their first championship in 88 years.
"Paul actually mentioned something to me in the dugout after I hit it," Crede said. "He said, 'You know the last two (first) pitches that this guy has thrown in this stadium have gone for grand slams.'"
The similarity between Saturday's game and his experience in the World Series wasn't lost on Qualls.
"Definitely. That happened. It was the first pitch and everything else," Qualls said. "I had to gain my composure. I knew it was a tie game still and I couldn't just let it fall apart there."
Rob Mackowiak led off the bottom of the 10th with a double off Dan Wheeler (1-5), pinch-hitter A.J. Pierzynski was walked intentionally, Juan Uribe sacrificed and Scott Podsednik got another intentional walk to load the bases.
Cintron then lined a 1-0 pitch to right to give the White Sox their 10th win in 11 interleague games this season and second straight over the Astros, who built a 5-1 lead behind rookie Taylor Buchholz.
After going 0-for-4 with two strikeouts, Cintron headed to the video room to look at himself on tape and noticed he was moving around too much at the plate.
"I figured out what I was doing wrong. I told Javier Vazquez, I told (Jim) Thome, I told Ozzie (Guillen) I was going to be the hero, so don't worry," Cintron said.
Matt Thornton (3-1) pitched 2 1/3 innings of relief for the win.
Buchholz left after the White Sox loaded the bases in the seventh on a walk to Thome, single by Konerko and a bloop single down the right field line by Jermaine Dye that was just out of the reach of second baseman Chris Burke and first baseman Mike Lamb.
Houston manager Phil Garner had no qualms calling on Qualls.
"It never crossed my mind. It wouldn't make any difference. If it had crossed my mind, I still would have brought him in," Garner said. "He's fine. I'll bring him in again. Sooner or later he's going to make the pitches and get them out."
Crede said he'd taken too many first-pitch strikes this season.
"I told Mackowiak when I was on-deck, I said, 'I'm swinging at the first pitch, no matter where it is,'" Crede said.
"He did his job. I didn't do mine," Qualls said.
Buchholz gave up four hits and four runs in 6 1/3 innings with one walk and eight strikeouts.
Lamb had four hits, including three doubles, for the Astros, who took a 5-1 lead against Chicago starter Jon Garland, thanks to a three-run fourth and a pair of hits that had deflected off Crede's glove.
Garland lasted five innings, giving up eight hits, five runs and five walks.
Willy Taveras hit back to Garland, who tried to start a double play but Taveras easily beat the throw to first as Palmeiro scored. Lamb's second double of the game scored Taveras for a 4-1 lead and Burke followed with an RBI single.
Chicago had the early lead when Podsednik singled, stole second, moved up on a grounder and scored on Thome's sacrifice fly in the first.
Morgan Ensberg had a two-out RBI single in the third to give the Astros a 2-1 lead.
- Guillen, the White Sox manager, ried to clear up his latest flap of a tumultuous week, saying he indeed will attend sensitivity training mandated by commissioner Bud Selig. Guillen launched into a diatribe and then got up and walked out of an interview room Friday night when asked about an ESPNdeportes.com report that quoted him as saying he likely would not undergo the training. Guillen was been fined and ordered to take the sensitivity training after calling a Chicago sports columnist a name that is derogatory to homosexuals. "I don't know when and how," Guillen said. "I say I got to take an English class before I do so I can understand what it really means. That's all. He (Selig) is the man, he's the boss. When the man says something, you have to do it."
- The crowd of 38,377 was the White Sox's 18th sellout of the season, tying the franchise record set last season.
- Craig Biggio, who has a sore shoulder, sat out the game but expects to play as the DH Sunday.