CHICAGO -- This time, A.J. Pierzynski landed the big hit.
The Cubs led 6-5 when Ross Gload singled on a slow roller that deflected off Dempster's calf. Shortstop Ronny Cedeno was unable to barehand it, and Jermaine Dye walked. That brought up Pierzynski, who knocked a 1-1 pitch out to right for his fifth homer, and the White Sox won for the 13th time in 15 games.
The game was delayed for about five minutes after Pierzynski's homer when agitated Cubs fans pelted the field with debris. The grounds crew at Wrigley Field cleaned up the cups, plastic bottles and other items before the game resumed.
Pierzynski barreled over Cubs catcher Michael Barrett on May 20 at U.S. Cellular Field. Barrett responded by grabbing Pierzynski and punching him in the face, setting off a bench-clearing brawl.
This time, Pierzynski showed no mercy on a hanging slider.
"It was nice. At same time it's just one game, just one win," he said. "But for all the stuff I've been through this weekend and everything that has gone on, it was kind of nice."
For Dempster and the Cubs, it was just more agony.
The blown save was the fifth in 17 chances for Dempster (1-5), and the Cubs have lost eight of nine.
"It's really embarrassing to go out there and perform the way I did after a good game like that," Dempster said. "To sit there and make mistakes like that, it's a tough pill to swallow. I'm a big boy, I'll get over it. But I don't want to sit here and give another interview (saying), 'It was tough, I'll get over it, and I'll bounce back.' I'm sick of doing those and I'm embarrassed that I've had to do as many as I've had to do."
Jacque Jones hit a tiebreaking solo homer in the seventh inning for the Cubs, and Aramis Ramirez drove in five runs.
Jones hit his 14th homer off reliever David Riske with two out in the seventh, after the White Sox's Paul Konerko tied it at 5 with a pinch-hit home run leading off the top half.
Ramirez hit a three-run homer off Javier Vazquez in the fifth to give the Cubs a 5-3 lead. He also had a two-run double off the left-field wall in the first and a triple into the right-field corner in the third.
The last Cub to hit for the cycle was Mark Grace on May 9, 1993, against San Diego.
Jim Thome hit a two-run drive in the fifth for his American League-leading 26th homer and Pierzynski and Joe Crede had three hits each for the White Sox.
Crede hit his 15th homer -- a solo shot off Greg Maddux in the sixth -- to cut the Cubs' lead to 5-4. Maddux allowed four runs and 10 hits in six innings but did not figure in the decision after losing his previous three starts.
Nor did the White Sox's Javier Vazquez, who had another rough time after allowing a season-high nine runs in six-plus innings in his previous outing against Houston. Vazquez gave up five runs and 11 hits in six innings against the Cubs before he was lifted for the pinch-hitting Konerko.
The slugger connected on a 3-2 pitch from Scott Eyre for his 20th homer of the season. It was the second pinch-hit homer of Konerko's career and his first since July 2, 2003, against Minnesota.
The Cubs regained the lead. Then, Pierzynski connected.
"It was a great at-bat by Gload, also a good at-bat by Dye," manager Ozzie Guillen said. "That's what the game is all about. When I saw A.J. I thought something special could happen here."
- RHP Kerry Wood will play catch and long toss over the next week as the Cubs try once again to get their injury-plagued starter ready to return to the mound. Wood began the season on the disabled list, made four starts and then went back to the DL after the shoulder began troubling him. He had surgery last August. On Monday, Wood went to see the Cincinnati doctor who did the operation and underwent bio-mechanical testing that showed he had a muscle imbalance in the shoulder. "We're definitely going to have to go backward as far as his endurance. There is no question about it," trainer Mark O'Neal said Saturday. "I'd say he's probably got a week's work of playing catch and long toss before we even think about doing anything on the mound."
- Ramirez's five RBI were one shy of a career high.
- Guillen said he expects to be criticized when All-Star selections are announced Sunday because, as usual, there will be some deserving players left off the AL roster. "I'm going to take the heat. But I don't pick this team myself," Guillen said. "One thing you have to remember, I have to pick the best guys to win the game." The league that wins the All-Star game will have home field advantage in the World Series and that was a big plus for the White Sox last year when they won the first two games at home against the Astros.