One inning after Clark tied the game with a two-run pinch hit homer in the ninth, Young hit a game-ending, two-run homer to defeat the Devil Rays 10-8 Tuesday night.
The Diamondbacks rallied from a six-run deficit for their first win in eight games against their 1998 expansion partners. Arizona trailed 7-1 in the fourth and 8-2 in the sixth.
"That was fun," Arizona manager Bob Melvin said. "Those feel a lot better when you win them. It ended up being a huge win for us. We finally beat the Devil Rays."
It was a crushing loss for Tampa Bay, which coughed up several late leads.
"It's unfortunate," manager Joe Maddon said. "Another huge lead goes away, and that's hard."
Opponents might want to think about pitching around Young the next time he comes up in the 10th inning. For the second time in two weeks, Arizona's center fielder hit a game-winning homer in the 10th.
"You can never get used to it, honestly," said Young, whose 10th-inning homer on June 5 beat San Francisco 4-3. "It's something that doesn't happen too often, but it feels great when it does."
"He battled very good, and I tried to go with the slider," Reyes said. "I left it up."
An inning earlier, Reyes blew his first save in 17 chances by serving up a game-tying, two-run shot to Clark. With one out, Reyes walked Carlos Quentin and then Clark hit a 2-1 changeup for his third pinch hit homer of the season and 10th of his career.
"You try to stay positive and you don't think you're going to blow a save," Reyes said.
It's the fourth time Arizona has rallied from six runs down to win, and the second time this season. The Diamondbacks overcame a 7-1 third inning deficit in a 9-8 victory at Pittsburgh May 19.
One of Arizona's few veterans, Clark said he urged his teammates to hang in there even as they fell behind early on.
"I mentioned earlier that you're not going to hit a five-run home run," Clark said. "So you simply try to put together solid at-bats, get a run here and a run there and hope you don't run out of outs."
Carlos Quentin homered and drove in three runs for the Diamondbacks, who left the bases loaded three times.
Akinori Iwamura led off the game with a homer and finished a triple shy of the cycle for Tampa Bay. He singled in the second and doubled in the fourth to help the Devil Rays build a 7-1 lead.
The Devil Rays pounced on Arizona starter Doug Davis. Iwamura belted Davis' first pitch of the game 384 feet into the left field seats for his first career leadoff homer. It was Iwamura's second homer of the season.
Davis allowed seven runs on nine hits in four innings, matching his shortest outing of the season. He walked one and struck out three, though he did break the majors' longest hitless streak with a single up the middle in the second. He had been 0-for-51 slump since getting a hit July 4 off Cincinnati's Bronson Arroyo.
"He didn't have good command," Melvin said. "When he threw the ball over the plate, he got hit."
Tampa Bay made it 7-1 in the fourth on Ty Wigginton's 404-foot homer to left field. The two-run shot was Wigginton's 12th.
Arizona pulled within 8-4 in the sixth on Quentin's solo homer -- his fifth -- and an RBI single by Orlando Hudson.
Broken-bat RBI singles by Quentin and Eric Byrnes off Jay Witasick made it 8-6 in the seventh.
Young said he and his teammates sensed then that they would complete the comeback.
"It's tough, but at the same time we understand that we have the skill to come back in a game like that as long as we don't give up," Young said.
- In the first two games of the series, Arizona starting pitchers Livan Hernandez and Davis gave up 13 runs and 21 hits in 10 innings.
- Wigginton's homer extended his hit streak to a career-long 13 games.