SAN DIEGO -- Dave Trembley couldn't hide the excitement of his first big league win.
For a night, anyway, the Orioles put aside the upheaval from a managerial change and a losing streak that had reached nine games.
Trembley was named interim manager on Monday after the Orioles fired Sam Perlozzo. The Orioles lost 12-6 in the series opener on Tuesday night.
"It's great for the Orioles," said Trembley, who spent the previous 20 seasons managing in the minors before becoming Baltimore's bullpen coach. "It's about the Baltimore Orioles and it's about Dave Trembley being the manager of the Baltimore Orioles, and I think it comes in that order.
"I told the team the first day it's a privilege to be the manager of the club. That's how it feels right now."
Trembley saved the lineup card, and catcher Paul Bako gave him the game ball.
Shortstop Miguel Tejada was hit on the left wrist by a pitch from reliever Doug Brocail in the four-run eighth, eventually scored and then left the game. X-rays were negative, but Tejada said he was going to a hospital to have a CAT scan.
"Miggy wanted to stay in the game, obviously, the kind of guy he is," Trembley said. "When I got over to first base and said, 'How do you feel?' he said, 'My legs are fine.' I wasn't concerned about his legs. I wanted to know about his wrist.
"Then when we scored some runs there, I thought it was more of a courtesy, out of respect to a guy like Tejada, to get him out of the game, we've got a day game tomorrow, let's get him iced, see how it is and then kind of go from there."
Guthrie shut down San Diego on four hits over eight innings.
The last-place Orioles handed Justin Germano his first loss in eight starts since coming up from the minor leagues, opening the game with three runs and four hits before the right-hander got his first out. Germano had won five straight decisions.
Guthrie and Germano were both waiver claims this year, and they came in with a combined record of 8-1. Guthrie was claimed from Cleveland on Jan. 29, while the Padres claimed Germano from Philadelphia on March 19.
Only one baserunner reached second base against Guthrie (4-1) before Russell Branyan hit an opposite-field homer to left on a 1-1 pitch leading off the eighth. Guthrie struck out nine and walked one.
"Their guy was as good as we've seen all year as far as making pitches and stuff," said Padres manager Bud Black, a former big league pitcher. "I saw him in Cleveland and he was not as composed as he was tonight. He looked like a completely different pitcher."
Guthrie had brief stints with the Indians each of the last three seasons.
"The big thing was coming out and shutting them down for a few innings to start the game and get that lead at 3-0," Guthrie said. "That's a good way to start it."
The right-hander said the Orioles handled the losing streak well.
"It really hasn't worn on us as much as it could. Hopefully we can stretch one win into a bunch before the break," he said.
Germano (5-1) trailed 3-0 after throwing 14 pitches.
Brian Roberts doubled into the left-field corner on Germano's second pitch and scored when Nick Markakis singled up the middle on the next pitch. Kevin Millar doubled into the left-field corner to bring in Markakis and Tejada doubled down the left-field line to score Millar.
After being visited by pitching coach Darren Balsley, Germano walked Melvin Mora before retiring the side. He allowed only two baserunners over the next five innings, on a walk and single.
Germano gave up three runs and five hits in six innings. He struck out a season-high seven and walked two.
The Orioles scored four runs off Doug Brocail in the eighth. Jay Payton, San Diego's center fielder in 2004, hit a two-run triple, Mora had an RBI single and Paul Bako beat out an infield single to bring in another run.
- The Padres obtained C Michael Barrett and $1.5 million from the Chicago Cubs for backup C Rob Bowen and minor league OF Kyler Burke. Manager Bud Black said Barrett will start in Thursday afternoon's series finale against the Orioles.