NEW YORK -- Most of the Tampa Bay Devil Rays cleared out of the visitor's clubhouse quickly Friday night, leaving a few stragglers to watch the highlights of their game against the Yankees.
"I think all three as they get more experience in this league are going to be high-end baseball players here," Devil Rays manager Joe Maddon said. "When you get young guys like that there's going to be problems. There's always some growing pains involved and I think all of them showed you tonight what they're capable of doing."
Upton went 3-for-6 with three RBI in his first career multihomer game and Tampa Bay beat Mike Mussina for the first time in eight starts at Yankee Stadium.
Jackson (2-9) allowed four singles and four walks over six shutout innings in his best start of the season. He struck out four to win for the first time since June 24.
"Once I got past the first couple innings, I was just making them put the ball in play," he said.
It was his first road victory since winning at San Francisco on Sept. 27, 2003, while with the Dodgers. His road winless streak of 14 starts and 26 games was the longest among current major league starters.
New York won three of four at Tampa Bay in its first series after the All-Star break before taking three of four against Toronto at home. But the Yankees got off to a rough start in the opener of another four-game set against the Devil Rays, who won for just fourth time in their last 17 road games.
"Every once in a while you get it handed to you," Mussina said. "Obviously I didn't pitch very well and we were kind of flat."
Shelley Duncan, who was promoted from Triple-A Scranton/Wilkes Barre before the game, singled in Cano in the Yankees' three-run eighth to pick up his first career hit and RBI. The son of Cardinals pitching coach Dave Duncan and brother of St. Louis outfielder Chris Duncan went 1-for-4 in his major league debut.
Mussina entered with a 7-0 record and a 1.07 ERA in seven career starts against the Devil Rays in the Bronx.
Tampa Bay pushed across two runs in the third before pitching coach Ron Guidry came out to visit Mussina with Carl Crawford on first and one out. Upton hit Mussina's next pitch into the first row of the upper deck in left to make it 4-0.
"That's probably the farthest, yeah," Upton said when asked where the drive ranked among his homers. "I just put a good swing on it and it just went."
The Devil Rays sent 10 batters to the plate in a five-run fifth, chasing Mussina. Edwar Ramirez replaced him and walked two to load the bases ahead of Navarro's homer, a drive into the seats in right that made it 9-0.
Mussina (4-7) went 4 2/3 innings and was charged with six runs and seven hits. He struck out five, walked three and is 2-6 with four no-decisions in his last 12 starts.
"It was an unusual start for Moose because he had a real good start in the first two innings," Torre said.
Ramirez walked four of the five batters he faced, threw only two strikes in 19 pitches and failed to record an out. He gave up three runs and one hit.
"There is no excuse," a distraught Ramirez said.
Mike Myers entered after Ramirez struggled and got Upton to ground out to end the inning as the crowd cheered sarcastically.
Tampa Bay finished with 13 hits and each player in its starting lineup reached base. Upton led off the ninth with his 11th homer.
Delmon Young walked and scored in the Devil Rays' three-run eighth but went 0-for-5, snapping an 11-game hitting streak.
- RHP Jason Hammel and LHP J.P. Howell will start for the Devil Rays in the doubleheader.
- New York's Melky Cabrera (mild stomach muscle strain) pinch hit in the eighth and struck out looking.
- The Yankees issued a season-high 10 walks.
- New York's Johnny Damon singled in the eighth to snap a career-worst 0-for-20 skid.
- The Yankees optioned OF Kevin Thompson to Scranton/Wilkes Barre and moved 1B Doug Mientkiewicz to the 60-day DL to make room for Duncan.