CLEVELAND -- Jeremy Guthrie blocked out his emotions, then shut down his former team.
"I just focused on what I had to do, blocked things out, and the guys got some big hits," said Guthrie, refusing to say he felt that he extracted any revenge on an Indians team that put him on waivers in January 2007.
The right-hander allowed only four hits and struck out four, showing the form that had Cleveland make him its first-round draft pick in 2002 out of Stanford. But Guthrie pitched only 16 times with one start for the Indians and was claimed by Baltimore.
"I had a sense of what this meant to him," Orioles manager Dave Trembley said. "He has worked hard to establish an identity as an Oriole, but he did tell me, 'It felt good.'
"Each time out, he is making a statement, establishing himself as a legitimate top-of-the-order starter in either league. I think he's still got some upside."
Guthrie gave up one run for the fourth time in a row and has yielded two or fewer in six of his past seven starts. In 10 starts since June 24, Guthrie is 7-1 with a 2.79 ERA.
"I'm feeling confident and have a deal of gratitude for progress," Guthrie said. "I'm very grateful. The guys got some big hits late to pad the lead."
Nick Markakis and Melvin Mora had three hits apiece for Baltimore. Markakis' two-run single in a four-run ninth made him 8-for-12 with eight RBI in the first three games of the four-game series.
Aubrey Huff had an RBI single in the ninth. He opened the Orioles' second by hitting his 25th homer, a drive off Anthony Reyes (1-1) that landed just over the wall and out of the reach of a leaping rightfielder Franklin Gutierrez and centerfielder Grady Sizemore.
Kevin Millar walked and eventually scored on a groundout by Jay Payton to make it 2-0 later in the inning.
Andy Marte opened the Indians' fifth with a double to left-center and scored on Sizemore's one-out double near the same spot on the warning track.
Reyes allowed two runs and six hits over six innings in his second AL start. The right-hander, acquired from St. Louis on July 26, was called up from Triple-A Buffalo on Friday to face Toronto and held the Blue Jays to one run and seven hits in 6 1/3 innings of a 5-2 victory.
Guthrie picked up an Orioles rotation that had allowed four first-inning runs in three straight losses and came in with a 6.13 ERA overall since the All-Star break.
It was Guthrie's first start and best performance against the Indians. In two relief outings against them a year ago, he allowed six runs in 1 1/3 innings.
"He threw the ball great. He was on top of his game," said Indians manager Eric Wedge, who before the game tried to explain that Guthrie's progress in Cleveland just didn't match up with the Indians' timetable. "I'm happy for him. He's a good kid. Sometimes it just isn't a guy's time with a team and he gets away. We've got players like that from other teams. It happens."
Orioles second baseman Brian Roberts went 0-for-5 to stop his hitting streak at 14 games. He was robbed of a hit by Cleveland second baseman Asdrubal Cabrera, who ranged behind the bag in the fifth to field a sharp grounder and threw to first to get the speedy Roberts.
Indians pitchers did not get a strikeout. According to the team, it was the first time that happened since April 28, 2004, at Chicago. ... Indians 2B Josh Barfield (left ring finger) is scheduled to start a rehab assignment at Double-A Akron on Thursday. C Victor Martinez (right elbow) is expected to join Akron on Friday. Both had surgery in June. ... Cleveland called up LHP Zach Jackson from Triple-A Buffalo and named him to start Thursday night. ... Markakis has hit .429 (24-for-56) with 20 RBI in his past 14 games. ... Mora went 3-for-5 and is 38-for-99 (.384) with six home runs and 32 RBI since the All-Star break. ... The Orioles have until midnight Friday to sign LHP Brian Matusz, their No. 1 draft pick and the fourth selection overall in June. ... Trembley said RHP Dennis Sarfate is still scheduled to start Saturday in Detroit. Sarfate has allowed 17 runs in 11 innings (13.90 ERA) in three starts.