SAN DIEGO -- Chad Reineke's major league debut was free of the nightmare scenarios he'd imagined the night before.
Reineke spent Friday night in his hotel room wondering how he would perform in his first big league game.
"To be honest, you kind of think about all the bad things that could happen to you," Reineke said. "You don't want to go two-thirds of an inning and be all over the place. In that aspect, I'm happy I was able to get a win."
Brian Giles drove in four runs for the first time this season to help Reineke survive after allowing two runs in a shaky first inning.
Reineke fell behind 3-1 in the fourth inning before San Diego scored five runs in the bottom of the inning, including the rookie pitcher's RBI single.
"I was impressed with how he bounced back from that first inning," Giles said. "He kept us in the baseball game."
Reineke was recalled from Triple-A Portland before the game to start in place of Chris Young, who was placed on the disabled list on Thursday. The right-hander gave up three runs and five hits with five strikeouts and three walks.
"He got through a very tough part of the order in the fifth," Black said. "That was a great sign when his pitch count was rising and he was probably tiring. He hung in there."
The Phillies fell two games behind the New York Mets in the NL East with their fifth loss in six games.
Reineke allowed a one-out walk to Jason Werth and a single by Chase Utley in the first before Ryan Howard's groundout scored a run. After a walk, Shane Victorino followed with an RBI single.
"It was kind of strange because with the first hitter you have some anxiety and nerves," Reineke said. "But I got him on two pitches. Then I started to miss the zone and I had to struggle. I think I was trying too hard."
Giles got a run back on the third with a sacrifice fly off Kyle Kendrick (10-7).
Greg Dobbs had a run-scoring double in the fourth to give the Phillies a 3-1 lead.
"We scored three runs early and couldn't polish him off," Philadelphia manager Charlie Manuel said. "He gutted it out."
Kendrick gave up a leadoff walk in the fourth to Chase Headley and then got the next two outs. But the right-hander gave up a run-scoring single to Reineke in his first major league at-bat.
"I was hoping he would throw me a fastball," said Reineke of the 3-2 pitch. "Luckily, I was able to flare the ball for a hit."
After the Padres loaded the bases again, Giles hit a three-run double into the right-field corner. Kevin Kouzmanoff followed with an RBI single off reliever Clay Condrey to put the Padres ahead 6-3.
"My mechanics are a little off and I have to work on that," Kendrick said. "I fell behind too many hitters. It's frustrating because it's usually been one inning."
Jody Gerut added two RBI with an eighth-inning double, his third hit of the game.
Kendrick got knocked out early for a second straight start, allowing six runs and six hits over 3 2/3 innings. He lasted 3 1/3 innings in his last start on Monday, an 8-6 loss at the Los Angeles Dodgers.
Reineke was acquired from Houston on July 22 in a trade for left-hander Randy Wolf.
Reineke was the third San Diego pitcher to get a hit in his major league debut, according to the Elias Sports Bureau. ... This is Reineke's second stint in the majors. Houston called him up on July 7, but he did not appear in a game before he was sent back to Round Rock the next day. ... The matchup on Friday night between Philadelphia's Jamie Moyer, 45, and San Diego's Greg Maddux, 42, was the seventh oldest pitching matchup (88 years, 30 days) in major league history, according to the Elias Sports Bureau. Four of the seven matchups have occurred since the start of last season and all have involved Moyer. ... In addition, the matchup of 40-somethings was the 51st since 1900 but only the second that was scoreless through six innings. The other game was on April 19, 1949 between Pittsburgh's Rip Sewell (41) and Chicago's Dutch Leonard (40).