Misch pitched seven solid innings for his first major league win and David Wright drove in three runs in his second start since coming off the disabled list, leading the New York Mets to an 8-3 win Thursday.
Catcher Josh Thole also picked up his first big league hit in his first major league start, a single in the second inning, followed by his first stolen base.
"Those are long dreams that are fulfilled before our very eyes," Mets manager Jerry Manuel said. "It's exciting seeing a guy get his first win in a game another guy gets his first hit in his first game."
The Mets avoided a three-game sweep by the Rockies, who kept their one-game lead over San Francisco in the NL wild-card race. The Giants lost 2-1 at Philadelphia on Thursday night.
Misch (1-1), who had gone 0-8 as a starter with San Francisco in 2007 and '08 and was waived by the Giants this summer, finally won in his 13th major league start and 55th appearance over four seasons.
"It's stuff you dream of and think about. I never thought it would take this long," said Misch, who was pacing in the dugout in the ninth. "I stayed out to watch until the game ended. I had to watch it. I didn't want it to end."
"I mentioned to him after his last outing that he reminded me of [Tom] Glavine early in his career: similar in style, throwing off-speed pitches at any time in the count," Manuel said.
Pedro Feliciano pitched the final two innings and surrendered Clint Barmes' 22nd homer, but it was another solo shot for the Rockies. The Mets responded with Daniel Murphy's two-run shot off Joe Beimel in the ninth.
"I did not know it was Pat's first victory until we got into here," Thole said in the clubhouse after the game. "One of my teammates said we have to share the lineup card. I'll give it all to him."
Misch allowed four hits, walked two and struck out three.
"We chased the ball up in the zone and we popped the ball up," Rockies manager Jim Tracy said. "He doesn't have an overwhelming fastball and I'm sure that the ball coming to our hitters looked attractive. But that's a popup pitch."
Wright went 3 for 4 in his second start since coming off the 15-day disabled list with a concussion courtesy of a Matt Cain fastball on Aug. 15.
"I felt like I was back on my game," Wright said.
The All-Star third baseman went back to his old batting helmet, ditching Rawlings' bulky, new S100 model that made him look like a bobblehead running the bases earlier in the series.
"It's just not comfortable," Wright said of the new helmet that will be required in the minors next season. "The last thing I need to worry about in the box is to try to shove it on my head. I will stay with the one I used today."
Wright's two-run double just inside the first-base bag highlighted a four-run fifth inning off Jason Marquis (14-10).
"It was one of my better pitches," Marquis said. "He put the barrel on it and was probably thinking right field and it sneaked by Todd [Helton]."
Wright's big hit was sandwiched by RBI singles from Angel Pagan and Jeff Francoeur. Marquis left after the inning and was charged with five runs and nine hits. He failed to tie his career high of 15 wins.
"He wasn't right today," Tracy said.
Neither were the Rockies' hitters, thanks to the crafty Misch.
"The key was I minimized the traffic on the bases," he said. "There wasn't any one on when they got the home runs.
"Josh called a great game. I thought we were on the same page most of the game."
- An MRI on Rockies closer Huston Street's ailing right arm was negative. Street was shut down Wednesday with biceps tendinitis. "Anytime your arm's not feeling good, that's the news you want to get, that it's just inflammation," Street said.
- Rockies CF Dexter Fowler (knee) will do a full workout Friday at Coors Field with the intention of starting a rehab assignment at Triple-A Colorado Springs on Saturday.