DENVER -- Jeff Francis has found a comfort level in Colorado's four-man rotation.

He threw six scoreless innings for the Rockies in a 10-2 win over the San Diego Padres on Friday.

Rex Brothers bailed out newly recalled Tyler Chatwood in the eighth before Michael Cuddyer and Wilin Rosario hit two-run homers in the bottom of that inning to secure Francis' first win in the majors since Sept. 15, 2011, when he was pitching for the Kansas City Royals.

Francis became the first Rockies starter to win since June 4, which is the last time the Rockies won consecutive games.

"I hope a lot of our young people are paying close attention as to what you can do with 75 or 80 pitches if you do it correctly," said Manager Jim Tracy, referring his starters' pitch limit.

Francis threw 82 pitches, 49 strikes, as he became the second Rockies starter to pitch six innings they implemented the four-man rotation June 19. The other was Christian Friedrich on June 22 at Texas.

The Rockies have won four of the five games started by Francis (1-1) who has allowed three runs in 16 innings in his past three starts. Asked the key to his recent success, Francis said, "just commanding both my curveball and changeup and being able to throw them for strikes and being able to throw them for a ball out of the zone when I need to."

Former Rockies pitcher Jason Marquis (1-4) held Colorado to two runs through five innings before they scored four in the sixth.

Tracy had seventh-inning specialist Brothers warming up with the Rockies leading by two runs but turned to Chatwood, called up earlier Friday from Triple-A Colorado Springs, in the seventh with the Rockies ahead by six runs. Tracy said he intended to have Chatwood finish the game.

But he allowed a leadoff homer to Carlos Quentin in the seventh and a run-scoring single to pinch hitter Will Venable in the eighth. Brothers came on with none out and runners on first and second to face the Padres No. 3, 4 and 5 hitters. He struck out Chase Headley and Quentin on sliders and got Yonder Alonso to line out.

"The pitch of the night actually is the 3-2 pitch to Chase Headley, the slider that struck Headley out," Tracy said. "Because if that's ball four, we've got a bases loaded situation with a 6-2 game and nobody out and Carlos Quentin standing up there at home plate. That's not where you want to be."

Since being recalled from Colorado Springs on June 2, Brothers has allowed two runs, one earned, in 13 2/3 innings with three walks and 21 strikeouts while stranding the eight runners he has inherited.

"I guess that's kind of the job description of the bullpen is to come in late in the game and lock things down," Brothers said. "My only mind set was to stop things right where they were."

The Rockies scored a run in the first and another in the third.

Marco Scutaro doubled with one out in the first, took third on a wild pitch and scored on Carlos Gonzalez's ground out. Scutaro's two-out single in the third scored Rosario, who led off with a single and was sacrificed to second by Francis.

Marquis began his third trip through the lineup in the sixth and proved vulnerable. He had allowed three hits to that point but gave up three straight extra-base hits in what became a four-run outburst with help from the Padres defense.

Dexter Fowler led off with a walk and was sacrificed to second by Scutaro. Gonzalez tripled into the right field corner and scored when second baseman Logan Forsythe's relay throw sailed into the stands. With two outs, shortstop Everth Cabrera misplayed Chris Nelson's grounder, and Colvin scored to make it 6-0.

"I threw quality pitches early in the game," Marquis said. "Then in the sixth inning, putting Dexter on with a walk, which you don't want to do. Then I wasn't able to put away Gonzalez and Cuddyer away with two strikes. I left two balls up. Probably the two mistakes all night and I paid for it."

Francis retired 10 batters in a row before Headley singled with one out in the fourth, but Francis got Quentin to ground into a double play.

John Baker led off the Padres sixth with a sharp grounder into right field for a single, the third and final hit off Francis. After Marquis' sacrifice, Francis issued his only walk, but Forsythe flied to left and Headley grounded to third.

"I used to be able to get a fastball by some guys, which I don't do anymore," said Francis, who underwent shoulder surgery in February 2009. "I have to find other ways."

Marquis, who went 15-13 with a 4.04 ERA for the Rockies in 2009, is 10-7 with a 3.78 at Coors Field in 22 games, 21 starts. In his past four starts, the Padres have scored a total of five runs.

"The only time I can control that aspect of the game is when I'm standing in the batter's box," Marquis said. "So I don't tend to worry about it too much. I've been around the game long enough. When you are younger it tends to bother you a little bit more. It is what it is. You can only control your job and that's what your focus should be."

Notes

To make room on the roster for Chatwood, the Rockies optioned left-hander Edwar Cabrera to Triple-A Colorado Springs two days after he struggled in his major league debut. ... Jhoulys Chacin (nerve irritation in chest muscle) threw a 30-pitch bullpen, all fastballs. He last pitched for the Rockies on May 1. Tracy said, "My understanding is there was a lot more coming out today. He is definitely progressing. I was pleased to hear that." ... Friedrich (4-5) will start for the Rockies against Edinson Volquez (4-7) of the Padres on Saturday.