Rose keyed a seven-point burst to open the fourth period, assisting on three straight field goals. John Lucas III hit a 3-pointer and Taj Gibson scored twice, opening up an 11-point lead for Chicago.
The Bulls are 5-0 at home for the first time since opening the 1996-97 season with seven straight wins at the United Center. Chicago has held its opponents to just 66.8 points game on its home court.
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Chicago was played its ninth game in 12 days, something the Bulls hadn't done since 1972. Chicago is 8-1 over that span.
Toronto played for the seventh time in nine nights.
Chicago led by four entering the fourth quarter, an unusually close game for a team that had won all four of its home games by an average of 20 points per game.
Rose took over with his playmaking, scoring just two points but notching five assists in the final period as Chicago went on a 19-6 run to start the period.
The Raptors didn't score from the foul line until Linas Kleiza made a free throw with 7:14 to go in the fourth. Toronto was just 1 for 7 from the line in game and was whistled for 15 fouls to only seven for Chicago.
Chicago shot 55 percent and led by 13 points in the opening period, but fell flat in the second, shooting just 30 percent from the floor.
Former Bulls player James Johnson capped a 10-2 second quarter surge with a jumper, putting Toronto ahead. Johnson scored 10 points in the first half, surpassing his season high of eight points for a full game.
Rose scored seven points in the first quarter and keyed a nine-point run with a pullup 3-pointer in transition as Chicago jumped out to a 23-14 lead.
The game was tied 37-all at the break and the pace didn't pick up much in the third. Rose scored seven points in the period, but both teams shot under 40 percent.
|Carlos Boozer is one of three starters for the Bulls that scores in double digits against Toronto. (AP)|
|Chicago (12-2) «||23||14||19||21||77|
|TOR:L. Barbosa 15 Pts
TOR:A. Johnson 13 Reb
TOR:J. Calderon 8 Ast
|CHI:D. Rose 18 Pts
CHI:C. Boozer 13 Reb
CHI:D. Rose 11 Ast
|Players of the Game|
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|D. DeRozan, SG||38||7-15||0-0||4||0||2||15|
|J. Calderon, PG||36||1-6||0-0||3||8||0||2|
|A. Johnson, SF||28||3-11||0-2||13||2||3||6|
|E. Davis, PF||17||1-3||0-2||5||0||1||2|
|R. Butler, SG||14||0-3||0-0||1||1||1||0|
|L. Barbosa, SG||34||7-20||0-1||6||1||0||15|
|J. Magloire, C||20||1-5||0-0||4||0||3||2|
|J. Johnson, PF||19||6-11||0-0||3||0||2||12|
|L. Kleiza, SF||18||2-6||1-2||3||0||2||5|
|G. Forbes, SF||16||2-6||0-0||8||5||1||5|
|A. Carter, PG||Did Not Play|
|A. Bargnani, C||Did Not Play|
|A. Gray, C||Did Not Play|
|J. Bayless, PG||Did Not Play|
|S. Alabi, C||Did Not Play|
|Complete Box Score|
|D. Rose, PG||41||7-20||2-2||4||11||0||18|
|L. Deng, SF||39||7-16||0-3||2||2||1||14|
|C. Boozer, PF||34||8-15||1-1||13||2||4||17|
|R. Brewer, SG||28||1-5||0-0||3||2||0||2|
|J. Noah, C||26||2-5||0-0||12||1||0||4|
|T. Gibson, PF||22||4-9||3-4||12||0||0||11|
|J. Lucas, PG||20||4-9||0-0||1||1||1||10|
|K. Korver, SG||16||0-3||0-0||3||0||0||0|
|O. Asik, C||14||0-0||1-2||2||0||1||1|
|R. Hamilton, SG||Did Not Play|
|B. Scalabrine, C||Did Not Play|
|M. James, PG||Did Not Play|
|C. Watson, PG||Did Not Play|
|J. Butler, SF||Did Not Play|
|Complete Box Score|