| Passing | ||||
| CP/AT | YDS | TD | INT | |
| P. Manning | 32/44 | 255 | 2 | 1 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| J. Addai | 16 | 70 | 0 | 23 |
| D. Rhodes | 7 | 21 | 0 | 13 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| A. Gonzalez | 6 | 95 | 1 | 29 |
| M. Harrison | 6 | 44 | 0 | 14 |
| R. Wayne | 2 | 34 | 0 | 26 |
| J. Addai | 7 | 31 | 0 | 8 |
| D. Clark | 6 | 30 | 0 | 8 |
| D. Rhodes | 5 | 21 | 1 | 13 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| R. Brock | 0 | 0 | 1 | 9 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| A. Vinatieri | 3/3 | 51 | 2/2 | 11 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| H. Smith | 3 | 40.3 | 3 | 54 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| K. Dawson | 1 | 11.0 | 0 | 11 |
| C. Simpson | 4 | 24.0 | 0 | 29 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| K. Ratliff | 1 | 3.0 | 0 | 3 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| F. Keiaho | 10-0 | 0.0 | 0 | 0 |
| G. Brackett | 7-1 | 0.0 | 0 | 0 |
| M. Bullitt | 7-1 | 0.0 | 0 | 0 |
| C. Session | 5-2 | 0.0 | 0 | 0 |
| A. Bethea | 3-0 | 0.0 | 0 | 0 |
| M. Giordano | 3-0 | 0.0 | 0 | 0 |
| K. Hayden | 3-3 | 0.0 | 0 | 0 |
| E. Foster | 2-1 | 0.5 | 0 | 0 |
| T. Jennings | 2-2 | 0.0 | 0 | 0 |
| R. Mathis | 2-1 | 1.5 | 0 | 1 |
| K. Ratliff | 2-0 | 0.0 | 0 | 0 |
| J. Senn | 2-0 | 0.0 | 0 | 0 |
| R. Brock | 1-0 | 0.0 | 0 | 0 |
| K. Dawson | 1-0 | 0.0 | 0 | 0 |
| P. Garcon | 1-0 | 0.0 | 0 | 0 |
| M. Harrison | 1-0 | 0.0 | 0 | 0 |
| A. Johnson | 1-0 | 0.0 | 0 | 0 |
| D. Reid | 1-0 | 0.0 | 0 | 0 |
| J. Silva | 1-0 | 0.0 | 0 | 0 |
| D. Freeney | 0-1 | 0.0 | 0 | 0 |
|
|
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| 4th Quarter | |
| San Diego at 1:35 | |
| 4-2-IND 29 | (1:35) N.Kaeding 47 yard field goal is GOOD, Center-D.Binn, Holder-M.Scifres. |
| N.Kaeding kicks 57 yards from SD 30 to IND 13. C.Simpson to IND 30 for 17 yards (A.Cason, B.Siler). | |
| Indianapolis at 1:26 | |
| 1-10-IND 30 | (1:26) (Shotgun) P.Manning pass short middle to A.Gonzalez to IND 43 for 13 yards (A.Cason) [M.Harris]. |
| 1-10-IND 43 | (1:05) (Shotgun) P.Manning pass incomplete short left to R.Wayne. |
| 2-10-IND 43 | (1:02) (Shotgun) P.Manning pass short right to D.Clark to IND 48 for 5 yards (Q.Jammer). |
| 3-5-IND 48 | (:41) (Shotgun) P.Manning pass short middle to M.Harrison to SD 47 for 5 yards (E.Weddle). The Replay Assistant challenged the first down ruling, and the play was REVERSED. (Shotgun) P.Manning pass short middle to M.Harrison to SD 48 for 4 yards (E.Weddle). |
| 4-1-SD 48 | (:26) P.Manning pass short left to M.Harrison to SD 34 for 14 yards (Q.Jammer). |
| 1-10-SD 34 | (:12) J.Addai up the middle to SD 33 for 1 yard (J.Cesaire, S.Cooper). |
| 2-9-SD 33 | (:02) P.Manning spiked the ball to stop the clock. |
| 3-9-SD 33 | (:02) A.Vinatieri 51 yard field goal is GOOD, Center-J.Snow, Holder-H.Smith. |
| 1st Quarter | ||
| FG | Adam Vinatieri 23 Yd, 1:42. Drive: 12 plays, 62 yards in 5:40. | |
| 2nd Quarter | ||
| FG | Nate Kaeding 35 Yd, 11:43. Drive: 9 plays, 66 yards in 4:59. | |
| TD | Vincent Jackson, 39 Yd pass from Philip Rivers (Nate Kaeding kick is good), 4:56. Drive: 9 plays, 89 yards in 4:35. | |
| TD | Anthony Gonzalez, 13 Yd pass from Peyton Manning (Adam Vinatieri kick is good), 0:38. Drive: 9 plays, 71 yards in 4:18. | |
| 3rd Quarter | ||
| TD | Dominic Rhodes, 1 Yd pass from Peyton Manning (Adam Vinatieri kick is good), 3:51. Drive: 13 plays, 66 yards in 7:10. | |
| 4th Quarter | ||
| FG | Adam Vinatieri 38 Yd, 11:48. Drive: 13 plays, 62 yards in 4:10. | |
| TD | Jacob Hester, 1 Yd pass from Philip Rivers (Nate Kaeding kick is good), 5:36. Drive: 12 plays, 70 yards in 6:12. | |
| FG | Nate Kaeding 47 Yd, 1:30. Drive: 8 plays, 58 yards in 1:45. | |
| FG | Adam Vinatieri 51 Yd, 0:00. Drive: 8 plays, 37 yards in 1:30. | |
| Passing | ||||
| CP/AT | YDS | TD | INT | |
| P. Rivers | 24/31 | 288 | 2 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| L. Tomlinson | 21 | 84 | 0 | 20 |
| D. Sproles | 2 | 21 | 0 | 21 |
| P. Rivers | 2 | 15 | 0 | 9 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| C. Chambers | 6 | 61 | 0 | 18 |
| V. Jackson | 2 | 57 | 1 | 39 |
| M. Floyd | 2 | 54 | 0 | 31 |
| L. Tomlinson | 3 | 30 | 0 | 15 |
| B. Manumaleuna | 3 | 29 | 0 | 13 |
| A. Gates | 3 | 28 | 0 | 13 |
| J. Hester | 3 | 16 | 1 | 9 |
| D. Sproles | 2 | 13 | 0 | 11 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| P. Rivers | 1 | 1 | 0 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| N. Kaeding | 2/2 | 47 | 2/2 | 8 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| M. Scifres | 3 | 41.0 | 1 | 45 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| D. Sproles | 5 | 20.2 | 0 | 26 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| D. Sproles | 1 | 4.0 | 0 | 4 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| Q. Jammer | 9-2 | 0.0 | 1 | 0 |
| J. Williams | 9-1 | 1.0 | 0 | 0 |
| E. Weddle | 8-2 | 0.0 | 0 | 0 |
| M. Wilhelm | 6-1 | 0.0 | 0 | 0 |
| C. Hart | 5-2 | 0.0 | 0 | 0 |
| A. Cason | 3-2 | 0.0 | 0 | 0 |
| A. Cromartie | 3-1 | 0.0 | 0 | 0 |
| J. Tucker | 3-1 | 0.0 | 0 | 0 |
| A. Applewhite | 2-0 | 0.0 | 0 | 0 |
| S. Cooper | 2-3 | 0.0 | 0 | 0 |
| I. Olshansky | 2-0 | 0.0 | 0 | 0 |
| S. Phillips | 2-2 | 0.0 | 0 | 0 |
| J. Cesaire | 1-1 | 0.0 | 0 | 0 |
| T. Dobbins | 1-0 | 0.0 | 0 | 0 |
| M. Goff | 1-0 | 0.0 | 0 | 0 |
| S. Gregory | 1-0 | 0.0 | 0 | 0 |
| K. Grennan | 1-0 | 0.0 | 0 | 0 |
| K. Osgood | 1-0 | 0.0 | 0 | 0 |
| A. Waters | 1-0 | 0.0 | 0 | 0 |
| J. Hester | 0-1 | 0.0 | 0 | 0 |
| B. Siler | 0-1 | 0.0 | 0 | 0 |
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