| Passing | ||||
| CP/AT | YDS | TD | INT | |
| P. Rivers | 22/39 | 298 | 2 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| R. Mathews | 19 | 75 | 0 | 15 |
| M. Tolbert | 2 | 26 | 0 | 23 |
| P. Rivers | 3 | 5 | 0 | 6 |
| D. Sproles | 5 | 3 | 0 | 3 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| L. Naanee | 5 | 110 | 1 | 59 |
| A. Gates | 5 | 76 | 1 | 34 |
| M. Floyd | 3 | 48 | 0 | 22 |
| R. McMichael | 2 | 28 | 0 | 20 |
| B. Davis | 2 | 26 | 0 | 22 |
| J. Hester | 2 | 6 | 0 | 3 |
| D. Sproles | 2 | 2 | 0 | 4 |
| R. Mathews | 1 | 2 | 0 | 2 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| P. Rivers | 2 | 0 | 1 | -6 |
| R. Mathews | 1 | 1 | 0 | 0 |
| J. Hester | 0 | 0 | 1 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| N. Kaeding | 0/0 | 0 | 2/2 | 2 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| M. Scifres | 8 | 47.8 | 0 | 60 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| D. Sproles | 2 | 16.0 | 0 | 19 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| D. Sproles | 5 | 6.6 | 0 | 13 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| S. Gregory | 7-0 | 0.0 | 0 | 0 |
| S. Phillips | 5-0 | 1.0 | 0 | 0 |
| K. Burnett | 5-1 | 0.0 | 0 | 0 |
| A. Cason | 4-1 | 0.0 | 0 | 0 |
| S. Cooper | 3-1 | 0.0 | 0 | 0 |
| C. Spillman | 3-0 | 0.0 | 0 | 0 |
| O. Nwagbuo | 3-0 | 0.0 | 0 | 0 |
| L. English | 2-1 | 0.0 | 0 | 0 |
| L. Naanee | 1-0 | 0.0 | 0 | 0 |
| R. McMichael | 1-0 | 0.0 | 0 | 0 |
| M. Scifres | 1-0 | 0.0 | 0 | 0 |
| M. Tolbert | 1-0 | 0.0 | 0 | 0 |
| J. Cesaire | 1-0 | 0.0 | 0 | 0 |
| A. Applewhite | 1-0 | 0.0 | 0 | 0 |
| A. Garay | 1-0 | 0.0 | 0 | 0 |
| E. Weddle | 1-0 | 0.0 | 0 | 0 |
| Q. Jammer | 1-0 | 0.0 | 0 | 0 |
| L. Castillo | 0-1 | 0.0 | 0 | 0 |
|
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| 4th Quarter | |
| San Diego at 4:12 | |
| 1-10-KC 45 | (4:12) (Shotgun) P.Rivers pass short middle to M.Floyd to KC 23 for 22 yards (D.Johnson). |
| 1-10-KC 23 | (3:26) D.Sproles left tackle to KC 25 for -2 yards (D.Johnson). |
| 2-12-KC 25 | (2:44) P.Rivers pass short middle to A.Gates to KC 16 for 9 yards (M.Vrabel). |
| 3-3-KC 16 | (2:00) (Shotgun) P.Rivers pass incomplete short left to M.Floyd (J.Arenas). |
| 4-3-KC 16 | (1:56) (Shotgun) P.Rivers pass short middle to L.Naanee to KC 4 for 12 yards (D.Washington). |
| 1-4-KC 4 | (1:14) (Shotgun) P.Rivers pass incomplete short left to M.Floyd (B.Carr). |
| 2-4-KC 4 | (1:08) (Shotgun) D.Sproles up the middle to KC 6 for -2 yards (G.Dorsey, R.Edwards). |
| 3-6-KC 6 | (:45) (Shotgun) P.Rivers pass incomplete short middle to M.Floyd. |
| 4-6-KC 6 | (:39) (Shotgun) P.Rivers pass incomplete short middle to M.Floyd [G.Dorsey]. |
| Kansas City at :33 | |
| 1-10-KC 6 | (:33) M.Cassel kneels to KC 5 for -1 yards. |
| 1st Quarter | ||
| TD | Antonio Gates, 3 Yd pass from Philip Rivers (Nate Kaeding kick is good), 1:52. Drive: 9 plays, 60 yards in 4:45. | |
| TD | Jamaal Charles, 56 Yd run (Ryan Succop kick is good), 0:37. Drive: 3 plays, 69 yards in 1:15. | |
| 2nd Quarter | ||
| TD | Tony Moeaki, 2 Yd pass from Matt Cassel (Ryan Succop kick is good), 5:55. Drive: 3 plays, 12 yards in 1:26. | |
| TD | Dexter McCluster, 94 Yd punt return (Ryan Succop kick is good), 1:43. | |
| 3rd Quarter | ||
| TD | Legedu Naanee, 59 Yd pass from Philip Rivers (Nate Kaeding kick is good), 2:23. Drive: 5 plays, 91 yards in 2:51. | |
| 4th Quarter | ||
| None | ||
| Passing | ||||
| CP/AT | YDS | TD | INT | |
| M. Cassel | 10/22 | 68 | 1 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| J. Charles | 11 | 92 | 1 | 56 |
| T. Jones | 11 | 39 | 0 | 10 |
| M. Cassel | 2 | 4 | 0 | 5 |
| D. McCluster | 1 | 0 | 0 | 0 |
| T. Castille | 1 | 0 | 0 | 0 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| T. Moeaki | 3 | 21 | 1 | 16 |
| C. Chambers | 1 | 14 | 0 | 14 |
| D. Bowe | 1 | 13 | 0 | 13 |
| D. McCluster | 2 | 9 | 0 | 5 |
| J. Charles | 1 | 8 | 0 | 8 |
| T. Castille | 2 | 3 | 0 | 3 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| D. McCluster | 1 | 0 | 1 | 0 |
| B. Carr | 0 | 0 | 1 | 23 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| R. Succop | 0/0 | 0 | 3/3 | 3 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| D. Colquitt | 9 | 38.2 | 3 | 51 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| J. Arenas | 3 | 19.7 | 0 | 26 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| J. Arenas | 2 | 30.0 | 0 | 36 |
| D. McCluster | 3 | 33.3 | 1 | 94 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| D. Johnson | 11-1 | 0.0 | 0 | 1 |
| E. Berry | 5-1 | 0.0 | 0 | 0 |
| G. Dorsey | 4-2 | 0.5 | 0 | 0 |
| B. Flowers | 4-0 | 0.0 | 0 | 0 |
| T. Jackson | 3-3 | 0.0 | 0 | 0 |
| M. Vrabel | 3-1 | 0.0 | 0 | 0 |
| T. Copper | 3-0 | 0.0 | 0 | 0 |
| J. Belcher | 3-1 | 0.0 | 0 | 0 |
| T. Hali | 3-2 | 0.5 | 0 | 0 |
| B. Carr | 2-0 | 0.0 | 0 | 0 |
| R. Langford | 2-0 | 0.0 | 0 | 0 |
| J. McGraw | 2-0 | 0.0 | 0 | 0 |
| S. Smith | 2-1 | 0.0 | 0 | 0 |
| T. Gafford | 1-1 | 0.0 | 0 | 0 |
| J. Arenas | 1-0 | 0.0 | 0 | 0 |
| J. O'Connell | 1-0 | 0.0 | 0 | 0 |
| R. Edwards | 1-4 | 0.0 | 0 | 0 |
| D. Williams | 1-0 | 0.0 | 0 | 0 |
| D. Washington | 1-0 | 0.0 | 0 | 0 |
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