| Passing | ||||
| CP/AT | YDS | TD | INT | |
| D. Brees | 40/63 | 462 | 4 | 2 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| C. Ivory | 9 | 23 | 0 | 7 |
| P. Thomas | 1 | 6 | 0 | 6 |
| D. Brees | 1 | 5 | 0 | 5 |
| D. Sproles | 3 | 3 | 0 | 2 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| M. Colston | 9 | 136 | 1 | 31 |
| D. Sproles | 15 | 119 | 1 | 44 |
| J. Graham | 5 | 103 | 2 | 66 |
| D. Henderson | 4 | 49 | 0 | 19 |
| R. Meachem | 3 | 18 | 0 | 8 |
| A. Arrington | 1 | 14 | 0 | 14 |
| M. Higgins | 1 | 10 | 0 | 10 |
| J. Collins | 1 | 8 | 0 | 8 |
| P. Thomas | 1 | 5 | 0 | 5 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| C. Roby | 1 | 1 | 0 | 0 |
| D. Sproles | 1 | 1 | 0 | 0 |
| P. Thomas | 1 | 1 | 0 | 0 |
| J. Vilma | 0 | 0 | 1 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| J. Kasay | 1/1 | 48 | 3/3 | 6 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| T. Morstead | 5 | 45.4 | 2 | 60 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| C. Roby | 3 | 7.7 | 0 | 17 |
| D. Sproles | 2 | 19.0 | 0 | 22 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| D. Sproles | 3 | 9.7 | 0 | 13 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| M. Jenkins | 8-0 | 1.0 | 0 | 0 |
| R. Harper | 7-1 | 1.5 | 0 | 1 |
| C. Jordan | 6-0 | 0.0 | 0 | 0 |
| T. Porter | 4-0 | 0.0 | 0 | 0 |
| P. Robinson | 4-0 | 0.0 | 0 | 0 |
| J. Dunbar | 4-0 | 0.0 | 0 | 0 |
| J. Vilma | 3-1 | 0.0 | 0 | 0 |
| K. Hall | 3-0 | 0.0 | 0 | 0 |
| S. Shanle | 2-2 | 0.0 | 0 | 0 |
| J. Charleston | 2-0 | 0.0 | 0 | 0 |
| M. Wilson | 2-1 | 1.5 | 0 | 1 |
| I. Abdul-Quddus | 2-0 | 0.0 | 0 | 0 |
| C. Roby | 1-0 | 0.0 | 0 | 0 |
| J. Evans | 1-0 | 0.0 | 0 | 0 |
| S. Ellis | 1-1 | 0.0 | 0 | 0 |
| P. Thomas | 1-0 | 0.0 | 0 | 0 |
| J. Greer | 1-0 | 0.0 | 0 | 0 |
| D. Henderson | 1-0 | 0.0 | 0 | 0 |
| W. Smith | 1-0 | 0.0 | 0 | 0 |
| S. Rogers | 1-0 | 0.0 | 0 | 0 |
| J. Casillas | 1-0 | 0.0 | 0 | 0 |
| T. Johnson | 0-1 | 0.0 | 0 | 0 |
|
|
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| 4th Quarter | |
| San Francisco at 1:32 | |
| 1-10-SF 15 | (1:32) (Shotgun) Alex Smith pass short left to F.Gore to SF 22 for 7 yards (R.Harper). Caught at SF 11. 11-yds YAC |
| 2-3-SF 22 | (1:07) (No Huddle, Shotgun) Alex Smith pass short middle to F.Gore to SF 33 for 11 yards (R.Harper). Caught at SF 25. 8-yds YAC |
| 1-10-SF 33 | (:44) Alex Smith pass incomplete deep right to B.Swain. |
| 2-10-SF 33 | (:40) (Shotgun) Alex Smith pass deep left to V.Davis to NO 20 for 47 yards (M.Jenkins). Caught at NO 45. 20-yds YAC |
| 1-10-NO 20 | (:31) (Shotgun) Alex Smith pass short left to F.Gore to NO 14 for 6 yards (S.Shanle). Caught at NO 20. 6-yds YAC |
| 2-4-NO 14 | (:20) Alex Smith spiked the ball to stop the clock. |
| 3-4-NO 14 | (:14) Alex Smith pass short middle to V.Davis for 14 yards, TOUCHDOWN. |
| D.Akers extra point is GOOD, Center-B.Jennings, Holder-A.Lee. | |
| D.Akers kicks 53 yards from SF 35 to NO 12. C.Roby to NO 16 for 4 yards. Lateral to M.Colston to NO 14 for -2 yards (C.Jones). | |
| New Orleans at :00 | |
| 1-10-NO 14 | (:00) D.Brees pass short right to D.Sproles to NO 17 for 3 yards. Lateral to R.Meachem to NO 18 for 1 yard (C.Spillman). |
| 1st Quarter | ||
| TD | Vernon Davis, 49 Yd pass from Alex Smith (David Akers kick is good), 2:08. Drive: 2 plays, 54 yards in 0:46. | |
| TD | Michael Crabtree, 4 Yd pass from Alex Smith (David Akers kick is good), 0:41. Drive: 3 plays, 4 yards in 0:15. | |
| 2nd Quarter | ||
| FG | David Akers, 25 Yd, 14:12. Drive: 4 plays, 6 yards in 1:23. | |
| TD | Jimmy Graham, 14 Yd pass from Drew Brees (John Kasay kick is good), 9:32. Drive: 9 plays, 80 yards in 4:40. | |
| TD | Marques Colston, 25 Yd pass from Drew Brees (John Kasay kick is good), 4:09. Drive: 7 plays, 66 yards in 3:04. | |
| 3rd Quarter | ||
| FG | David Akers, 41 Yd, 10:36. Drive: 4 plays, 3 yards in 0:59. | |
| 4th Quarter | ||
| FG | John Kasay, 48 Yd, 13:08. Drive: 9 plays, 37 yards in 3:26. | |
| FG | David Akers, 37 Yd, 7:36. Drive: 5 plays, 45 yards in 3:02. | |
| TD | Darren Sproles, 44 Yd pass from Drew Brees (John Kasay kick is good), 4:02. Drive: 9 plays, 79 yards in 3:34. | |
| TD | Alex Smith, 28 Yd run (Frank Gore Run for 2 Pt. Conversion failed), 2:11. Drive: 6 plays, 80 yards in 1:51. | |
| TD | Jimmy Graham, 66 Yd pass from Drew Brees (Drew Brees pass to Darren Sproles for 2 Pt. Conversion), 1:37. Drive: 4 plays, 88 yards in 0:34. | |
| TD | Vernon Davis, 14 Yd pass from Alex Smith (David Akers kick is good), 0:09. Drive: 7 plays, 85 yards in 1:28. | |
| Passing | ||||
| CP/AT | YDS | TD | INT | |
| A. Smith | 24/42 | 299 | 3 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| F. Gore | 13 | 89 | 0 | 42 |
| A. Smith | 1 | 28 | 1 | 28 |
| K. Hunter | 6 | 23 | 0 | 11 |
| T. Ginn | 1 | 3 | 0 | 3 |
| A. Dixon | 1 | 0 | 0 | 0 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| V. Davis | 7 | 180 | 2 | 49 |
| F. Gore | 7 | 38 | 0 | 11 |
| M. Crabtree | 4 | 25 | 1 | 9 |
| B. Miller | 1 | 16 | 0 | 16 |
| K. Hunter | 1 | 13 | 0 | 13 |
| K. Williams | 2 | 12 | 0 | 6 |
| T. Ginn | 1 | 11 | 0 | 11 |
| J. Peelle | 1 | 4 | 0 | 4 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| A. Smith | 2 | 1 | 1 | 0 |
| F. Gore | 1 | 0 | 1 | -6 |
| P. Willis | 0 | 0 | 1 | 0 |
| B. Costanzo | 0 | 0 | 1 | 0 |
| C. Jones | 0 | 0 | 1 | 1 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| D. Akers | 3/3 | 41 | 3/3 | 12 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| A. Lee | 8 | 49.5 | 4 | 63 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| K. Hunter | 1 | 25.0 | 0 | 25 |
| K. Williams | 1 | 20.0 | 0 | 20 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| T. Ginn | 2 | 11.5 | 0 | 16 |
| K. Williams | 1 | 6.0 | 0 | 6 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| D. Goldson | 11-0 | 0.0 | 1 | 0 |
| N. Bowman | 10-1 | 0.0 | 0 | 0 |
| P. Willis | 8-0 | 0.0 | 0 | 0 |
| D. Whitner | 4-1 | 0.0 | 0 | 1 |
| C. Culliver | 3-1 | 0.0 | 0 | 0 |
| T. Brown | 3-1 | 0.0 | 1 | 0 |
| C. Spillman | 3-0 | 0.0 | 0 | 0 |
| A. Brooks | 3-1 | 1.0 | 0 | 0 |
| A. Smith | 3-0 | 1.0 | 0 | 0 |
| C. Rogers | 2-0 | 0.0 | 0 | 0 |
| J. Smith | 2-1 | 1.0 | 0 | 0 |
| C. Jones | 2-0 | 0.0 | 0 | 0 |
| R. Smith | 1-0 | 0.0 | 0 | 0 |
| P. Haralson | 1-0 | 0.0 | 0 | 0 |
| B. Costanzo | 1-0 | 0.0 | 0 | 1 |
| M. Williams | 1-0 | 0.0 | 0 | 1 |
| A. Smith | 1-0 | 0.0 | 0 | 0 |
| T. Gooden | 1-0 | 0.0 | 0 | 0 |
| B. Miller | 0-1 | 0.0 | 0 | 0 |
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