| Passing | ||||
| CP/AT | YDS | TD | INT | |
| R. Fitzpatrick | 18/32 | 153 | 0 | 0 |
| B. Smith | 0/1 | 0 | 0 | 1 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| C. Spiller | 12 | 88 | 1 | 33 |
| F. Jackson | 16 | 53 | 1 | 7 |
| B. Smith | 2 | 19 | 0 | 16 |
| R. Fitzpatrick | 3 | 5 | 0 | 4 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| S. Johnson | 6 | 82 | 0 | 23 |
| F. Jackson | 5 | 30 | 0 | 12 |
| C. Spiller | 4 | 22 | 0 | 11 |
| D. Jones | 1 | 9 | 0 | 9 |
| T. Graham | 1 | 6 | 0 | 6 |
| S. Chandler | 1 | 4 | 0 | 4 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| F. Jackson | 1 | 1 | 0 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| R. Lindell | 1/1 | 25 | 2/2 | 5 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| S. Powell | 8 | 44.0 | 2 | 62 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| L. McKelvin | 2 | 27.5 | 0 | 33 |
| B. Smith | 1 | 31.0 | 0 | 31 |
| L. Smith | 1 | 0.0 | 0 | 0 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| L. McKelvin | 2 | 5.0 | 0 | 10 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| K. Sheppard | 7-2 | 0.0 | 0 | 0 |
| C. Kelsay | 6-1 | 1.0 | 0 | 0 |
| G. Wilson | 6-1 | 0.0 | 0 | 0 |
| S. Gilmore | 4-1 | 0.0 | 0 | 0 |
| J. Byrd | 4-0 | 0.0 | 2 | 0 |
| N. Barnett | 4-2 | 2.0 | 0 | 0 |
| B. Scott | 4-1 | 0.0 | 0 | 0 |
| M. Williams | 3-0 | 2.0 | 0 | 0 |
| J. Rogers | 2-0 | 0.0 | 0 | 0 |
| A. Williams | 2-0 | 0.0 | 0 | 0 |
| L. McKelvin | 2-0 | 0.0 | 0 | 0 |
| C. White | 2-0 | 0.0 | 0 | 0 |
| N. Bradham | 2-1 | 0.0 | 0 | 0 |
| T. Choice | 1-0 | 0.0 | 0 | 0 |
| E. Pears | 1-0 | 0.0 | 0 | 0 |
| M. Dareus | 1-2 | 0.0 | 0 | 0 |
| E. Wood | 0-1 | 0.0 | 0 | 0 |
| A. Carrington | 0-1 | 0.0 | 0 | 0 |
| C. Rinehart | 0-1 | 0.0 | 0 | 0 |
| 1 | 2 | 3 | 4 | OT | |
| Buffalo | 9 | 0 | 7 | 0 | 3 |
| Arizona | 3 | 7 | 3 | 3 | 0 |
| 1st Quarter | ||
| FG @ 13:50 | Jay Feely makes a 49 yard kick. Drive: 4 plays, 2 yards in 0:55. | |
| SAFETY @ 8:36 | Chris Kelsay. | |
| TD @ 3:35 | C.J. Spiller runs for 10 yards (Rian Lindell kick is good). Drive: 10 plays, 49 yards in 5:01. | |
| 2nd Quarter | ||
| TD @ 4:47 | Larry Fitzgerald catches a 9 yard pass from Kevin Kolb (Jay Feely kick is good). Drive: 10 plays, 67 yards in 5:38. | |
| 3rd Quarter | ||
| FG @ 3:12 | Jay Feely makes a 49 yard kick. Drive: 12 plays, 43 yards in 6:18. | |
| TD @ 0:27 | Fred Jackson runs for 1 yard (Rian Lindell kick is good). Drive: 5 plays, 80 yards in 2:45. | |
| 4th Quarter | ||
| FG @ 1:09 | Jay Feely makes a 61 yard kick. Drive: 10 plays, 42 yards in 1:58. | |
| Overtime | ||
| FG @ 11:10 | Rian Lindell makes a 25 yard kick. Drive: 2 plays, -1 yards in 0:45. | |
| OT | |
| 2-10-ARI 35 | (13:14) (Shotgun) R.Fitzpatrick pass incomplete short left to T.Graham (P.Peterson). |
| 3-10-ARI 35 | (13:08) (Shotgun) R.Fitzpatrick pass incomplete short right to F.Jackson (D.Dockett). |
| 4-10-ARI 35 | (13:03) (Punt formation) PENALTY on BUF-A.Moats, False Start, 5 yards, enforced at ARZ 35 - No Play. |
| 4-10-ARI 35 | (13:08) (Punt formation) PENALTY on BUF-A.Moats, False Start, 5 yards, enforced at ARZ 35 - No Play. |
| 4-15-ARI 40 | (13:03) S.Powell punts 40 yards to end zone, Center-G.Sanborn, Touchback. The Replay Assistant challenged the kick touched ruling, and the play was Upheld. |
| 1-10-ARI 20 | (12:53) L.Stephens-Howling left tackle to ARZ 20 for no gain (C.Kelsay). |
| 2-10-ARI 20 | (12:13) J.Skelton pass incomplete short right to L.Stephens-Howling. |
| 3-10-ARI 20 | (12:08) (Shotgun) J.Skelton pass short middle intended for R.Housler INTERCEPTED by J.Byrd at ARZ 35. J.Byrd to ARZ 6 for 29 yards (M.Floyd). |
| 1-6-ARI 6 | (11:55) R.Fitzpatrick scrambles right tackle to ARZ 7 for -1 yards (C.Campbell). |
| 2-7-ARI 7 | (11:13) R.Lindell 25 yard field goal is GOOD, Center-G.Sanborn, Holder-S.Powell. |
| Passing | ||||
| CP/AT | YDS | TD | INT | |
| K. Kolb | 14/26 | 128 | 1 | 1 |
| J. Skelton | 2/10 | 45 | 0 | 1 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| W. Powell | 13 | 70 | 0 | 17 |
| K. Kolb | 5 | 66 | 0 | 22 |
| R. Johnson | 1 | 24 | 0 | 24 |
| L. Stephens-Howling | 11 | 22 | 0 | 11 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| L. Fitzgerald | 6 | 93 | 1 | 28 |
| M. Floyd | 1 | 24 | 0 | 24 |
| A. Roberts | 2 | 18 | 0 | 16 |
| R. Housler | 2 | 12 | 0 | 6 |
| J. King | 2 | 10 | 0 | 9 |
| W. Powell | 1 | 8 | 0 | 8 |
| R. Maui'a | 1 | 7 | 0 | 7 |
| E. Doucet | 1 | 1 | 0 | 1 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| W. Gay | 0 | 0 | 1 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| J. Feely | 3/4 | 61 | 1/1 | 10 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| D. Zastudil | 5 | 51.8 | 1 | 61 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| W. Powell | 2 | 24.5 | 0 | 32 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| P. Peterson | 3 | 12.0 | 0 | 20 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| D. Washington | 12-2 | 0.0 | 0 | 1 |
| O. Schofield | 6-1 | 2.0 | 0 | 0 |
| J. Fleming | 6-0 | 0.0 | 0 | 0 |
| C. Campbell | 5-0 | 0.0 | 0 | 0 |
| K. Rhodes | 4-0 | 0.0 | 0 | 0 |
| P. Peterson | 4-0 | 0.0 | 1 | 0 |
| A. Wilson | 3-1 | 0.0 | 0 | 0 |
| P. Lenon | 3-2 | 0.0 | 0 | 0 |
| W. Gay | 2-2 | 0.0 | 0 | 0 |
| J. Sanders | 2-0 | 0.0 | 0 | 0 |
| J. Bethel | 1-0 | 0.0 | 0 | 0 |
| J. Westerman | 1-0 | 0.0 | 0 | 0 |
| M. Floyd | 1-0 | 0.0 | 0 | 0 |
| W. Powell | 1-0 | 0.0 | 0 | 0 |
| R. Johnson | 1-0 | 0.0 | 0 | 0 |
| D. Dockett | 1-0 | 0.0 | 0 | 0 |
| D. Zastudil | 1-0 | 0.0 | 0 | 0 |
| S. Acho | 0-1 | 0.0 | 0 | 0 |
| D. Williams | 0-1 | 0.0 | 0 | 0 |
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