| Passing | ||||
| CP/AT | YDS | TD | INT | |
| C. Kaepernick | 16/21 | 233 | 1 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| F. Gore | 21 | 90 | 2 | 11 |
| L. James | 5 | 34 | 1 | 15 |
| C. Kaepernick | 2 | 21 | 0 | 23 |
| A. Dixon | 1 | 4 | 0 | 4 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| V. Davis | 5 | 106 | 1 | 31 |
| M. Crabtree | 6 | 57 | 0 | 33 |
| R. Moss | 3 | 46 | 0 | 21 |
| D. Walker | 1 | 20 | 0 | 20 |
| L. James | 1 | 4 | 0 | 4 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| Kicking | ||||
| FG | LG | XP | PTS | |
| D. Akers | 0/1 | 0 | 4/4 | 4 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| A. Lee | 3 | 50.3 | 1 | 62 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| L. James | 3 | 21.3 | 0 | 25 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| T. Ginn | 1 | 20.0 | 0 | 20 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| P. Willis | 11-1 | 0.0 | 0 | 0 |
| T. Brown | 8-0 | 0.0 | 0 | 0 |
| J. Smith | 4-0 | 0.0 | 0 | 0 |
| C. Culliver | 4-0 | 0.0 | 1 | 0 |
| C. Rogers | 4-0 | 0.0 | 0 | 0 |
| D. Goldson | 4-1 | 0.0 | 0 | 0 |
| I. Sopoaga | 3-0 | 1.0 | 0 | 0 |
| R. McDonald | 3-2 | 0.0 | 0 | 0 |
| M. Wilhoite | 2-0 | 0.0 | 0 | 0 |
| N. Bowman | 2-2 | 0.0 | 0 | 0 |
| D. Whitner | 2-0 | 0.0 | 0 | 0 |
| A. Smith | 1-0 | 0.0 | 0 | 0 |
| T. Brock | 1-0 | 0.0 | 0 | 0 |
| P. Cox | 1-0 | 0.0 | 0 | 0 |
| 1 | 2 | 3 | 4 | |
| San Francisco | 0 | 14 | 7 | 7 |
| Atlanta | 10 | 14 | 0 | 0 |
| 1st Quarter | ||
 | TD @ 11:24 | Julio Jones catches a 46 yard pass from Matt Ryan (Matt Bryant kick is good). Drive: 7 plays, 80 yards in 03:36. |
| FG @ 3:20 | Matt Bryant makes a 35 yard kick. Drive: 11 plays, 65 yards in 06:37. |
| 2nd Quarter | ||
| TD @ 14:57 | Julio Jones catches a 20 yard pass from Matt Ryan (Matt Bryant kick is good). Drive: 4 plays, 57 yards in 02:31. |
 | TD @ 8:08 | LaMichael James runs for 15 yards (David Akers kick is good). Drive: 11 plays, 75 yards in 06:49. |
| TD @ 1:55 | Vernon Davis catches a 4 yard pass from Colin Kaepernick (David Akers kick is good). Drive: 7 plays, 76 yards in 04:37. |
| TD @ 0:25 | Tony Gonzalez catches a 10 yard pass from Matt Ryan (Matt Bryant kick is good). Drive: 7 plays, 75 yards in 01:30. |
| 3rd Quarter | ||
| TD @ 10:47 | Frank Gore runs for 5 yards (David Akers kick is good). Drive: 7 plays, 82 yards in 04:13. |
| 4th Quarter | ||
| TD @ 8:23 | Frank Gore runs for 9 yards (David Akers kick is good). Drive: 6 plays, 38 yards in 03:36. |
| 4th Quarter | |
| Atlanta | |
| 1-10-SF 16 | (2:23) Jacquizz Rodgers rushed for 1 yard. |
| 2-9-SF 15 | (2:00) Matt Ryan passed to Jason Snelling for 5 yards. |
| 3-4-SF 10 | (1:15) Matt Ryan passed incomplete. |
| 4-4-SF 10 | (1:10) Matt Ryan passed incomplete to Roddy White. |
| San Francisco at 1:09 | |
| 1-10-SF 10 | (1:09) Frank Gore rushed for 3 yards. |
| 2-7-SF 13 | (1:04) SF was penalized 5 yards. |
| 2-12-SF 8 | (1:04) Frank Gore lost 3 yards. |
| 3-15-SF 5 | (1:00) Frank Gore rushed for 10 yards. |
| 4-5-SF 15 | (0:13) Andy Lee punted for 42 yards. Harry Douglas returned a punt for a 2 yard loss. |
| Atlanta at 0:05 | |
| 1-10-ATL 41 | (0:05) Matt Ryan passed to Julio Jones for 24 yards. |
| Passing | ||||
| CP/AT | YDS | TD | INT | |
| M. Ryan | 30/42 | 396 | 3 | 1 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| J. Rodgers | 10 | 32 | 0 | 9 |
| M. Turner | 8 | 30 | 0 | 10 |
| J. Snelling | 2 | 12 | 0 | 12 |
| M. Cox | 1 | 4 | 0 | 4 |
| M. Ryan | 2 | 3 | 0 | 3 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| J. Jones | 11 | 182 | 2 | 46 |
| R. White | 7 | 100 | 0 | 23 |
| T. Gonzalez | 8 | 78 | 1 | 16 |
| H. Douglas | 3 | 31 | 0 | 22 |
| J. Snelling | 1 | 5 | 0 | 5 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| Kicking | ||||
| FG | LG | XP | PTS | |
| M. Bryant | 1/1 | 35 | 3/3 | 6 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| M. Bosher | 2 | 45.0 | 1 | 48 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| H. Douglas | 3 | 2.0 | 0 | 6 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| T. DeCoud | 5-3 | 0.0 | 0 | 0 |
| A. Dent | 5-3 | 0.0 | 0 | 0 |
| D. Robinson | 5-0 | 0.0 | 0 | 0 |
| A. Samuel | 4-0 | 0.0 | 0 | 0 |
| S. Weatherspoon | 3-2 | 0.0 | 0 | 0 |
| J. Babineaux | 3-1 | 0.0 | 0 | 0 |
| S. Nicholas | 2-1 | 0.0 | 0 | 0 |
| C. Peters | 2-1 | 1.0 | 0 | 0 |
| K. Biermann | 2-0 | 0.0 | 0 | 0 |
| R. James | 1-0 | 0.0 | 0 | 0 |
| D. Davis | 1-0 | 0.0 | 0 | 0 |
| W. Moore | 1-5 | 0.0 | 0 | 0 |
| C. Owens | 1-0 | 0.0 | 0 | 0 |
| M. Ryan | 1-0 | 0.0 | 0 | 0 |
| H. Douglas | 1-0 | 0.0 | 0 | 0 |
| P. Jerry | 1-0 | 0.0 | 0 | 0 |
| V. Walker | 1-1 | 0.0 | 0 | 0 |
| C. Hope | 0-1 | 0.0 | 0 | 0 |
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