Harper (concussion) has been ruled out for the rest of Thursday's contest against the Vikings.
Harper suffered a head injury in the second half, and he has now been diagnosed with a concussion. In his absence, Jalen Mills and Daniel Thomas will continue to operate in elevated roles in Detroit's secondary.
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Lions' Alex Anzalone: Done for day
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Anzalone has been ruled out for the remainder of Thursday's contest against the Vikings after suffering a concussion.
Anzalone took a blow to the head in the second half, ultimately suffering a concussion. In his absence, Malcolm Rodriguez will continue to operate in a more significant role at linebacker versus Minnesota.
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Lions' Alex Anzalone: Being evaluated for concussion
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Anzalone (head) is being evaluated for a concussion during Thursday's contest against the Vikings.
Anzalone will not be eligible to return to Thursday's divisional matchup if he is diagnosed with a concussion and placed in the NFL's five-step protocol. Prior to leaving the field to be evaluated late in the third quarter, Anzalone had racked up two tackles (one solo) including 1.0 sacks.
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Lions' Thomas Harper: Evaluated for possible concussion
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Harper (head) is being evaluated for a concussion during Thursday's matchup against the Vikings.
Harper won't be able to return to action Thursday if he's officially placed in the NFL's concussion protocol. Jalen Mills and Daniel Thomas will both be candidates to handle expanded roles on defense if Harper is not cleared to retake the field Christmas Day.
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Lions' Alim McNeill: Questionable to return
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McNeill (abdomen) is questionable to return to Thursday's game against the Vikings.
McNeill was initially listed as questionable for Thursday's contest due to an abdomen issue, and although he was initially cleared to play, it appears that the same injury is now preventing the defensive lineman from retaking the field. Tyleik Williams and Roy Lopez will be candidates to handle increased defensive snaps as long as McNeill remains sidelined.
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Lions' Alim McNeill: Cleared to play Christmas Day
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McNeill (abdomen) is active for Thursday's game against the Vikings.
McNeill was limited in practice this week due to an abdominal injury, but the fifth-year pro has been cleared to play Thursday. He has accumulated 14 tackles (five solo), including 1.0 sacks, one pass defense and one forced fumble through nine regular-season games.
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Lions' Marcus Davenport: Active to face Vikings
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Davenport (shoulder) is active for Thursday's contest against Minnesota.
Davenport was limited in practice leading up to Thursday's divisional clash, but he's ultimately earned the green light to suit up Christmas Day. Across six regular-season appearances so far, Davenport has totaled 10 tackles (four solo) including 1.0 sacks.
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Lions' Al-Quadin Muhammad: Good to go Thursday
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Muhammad (abdomen) is active for Thursday's game against the Vikings.
Muhammad was initially listed as questionable, but he's ready to suit up Christmas Day. The starting defensive end has racked up 23 tackles (13 solo), including 9.0 sacks, across 15 regular-season appearances in 2025.
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Lions' Amik Robertson: Good to go vs. Minnesota
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Robertson (hand) is active for Thursday's game against the Vikings.
Robertson was able to play through a hand injury against the Steelers in Week 16, and the sixth-year pro will do so again Christmas Day. He has accumulated 31 tackles (25 solo), nine pass defenses and one forced fumble in the eight games since the Lions' Week 8 bye.
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Lions' Alim McNeill: Questionable to face Minnesota
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McNeill (abdomen) is listed as questionable for Thursday's game against the Vikings.
McNeill was limited in all three walkthrough practices due to an abdominal injury, and his status for Christmas Day will be official approximately 90 minutes prior to the 4:30 p.m. ET kickoff, when Detroit announces its list of inactive players. Roy Lopez and Tyleik Williams would be in line for more snaps at defensive tackle alongside DJ Reader if McNeill is unable to play.
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Lions' Al-Quadin Muhammad: Questionable for Christmas Day
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Muhammad (abdomen) is listed as questionable for Thursday's game against the Vikings.
Muhammad drew the questionable tag for Christmas Day after being limited in all three walkthrough practices. His status for Thursday's NFC North tilt may not be officially known until the Lions announce their list of inactive players approximately 90 minutes before the 4:30 p.m. ET kickoff. Tyrus Wheat and Marcus Davenport (shoulder) would be in line for more defensive snaps if Muhammad is not able to play.
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Lions' Avonte Maddox: Ruled out for Christmas Day
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Maddox (back/illness) has been ruled out for Thursday's game against the Vikings.
Maddox did not participate in any of the Lions' walkthrough practices due to a back injury and illness, which will prevent him from playing Christmas Day. His absence means Daniel Thomas or Jalen Mills will start at safety alongside Thomas Harper. Maddox's next chance to play is in the Lions' regular-season finale against the Bears in Week 18.
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Lions' Amik Robertson: Tagged as questionable Week 17
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Robertson (hand) is listed as questionable for Thursday's game against the Vikings.
Robertson earned the questionable tag for Christmas Day after being a limited participant in walkthrough practices, but he was able to play through a hand injury during Sunday's loss to the Steelers. Arthur Maulet would be poised to step into a larger role in the secondary if Robertson is unable to play.
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Lions' Marcus Davenport: Limited to open Week 17 prep
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Davenport (shoulder) was a limited participant in Tuesday's walkthrough practice.
Davenport has opened the week with back-to-back limited sessions due to a shoulder injury that he picked up during the Lions' 29-24 loss to the Steelers on Sunday. The Lions will hold their last practice Wednesday, and if Davenport is a full participant in that session, he would likely avoid an injury designation for Detroit's Christmas Day clash against Minnesota.
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Lions' Alex Anzalone: Eight tackles in Week 16 loss
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Anzalone recorded eight tackles (three solo) and one pass breakup in Detroit's loss to the Steelers on Sunday.
Anzalone has started all 15 games this season and has produced 92 tackles (50 solo), including 1.5 sacks, and nine pass breakups, including one interception, on 98 percent of the defensive snaps.
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Lions' Aidan Hutchinson: Pair of sacks in loss
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Hutchinson recorded three tackles (three solo), including 2.0 sacks, in the Lions' loss to the Steelers on Sunday.
Hutchinson has now matched his career-high with 11.5 sacks this season. Through 15 games, Hutchinson has recored 42 tackles (28 solo), four forced fumbles, three pass breakups, including one interception, and one fumble recovery on 91 percent of the Lions' defensive snaps.
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Lions' Jack Campbell: Season-high 16 tackles in loss
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Campbell recorded 16 tackles (seven solo), two pass breakups and one fumble recovery in Detroit's loss to Pittsburgh on Sunday.
The 16 tackles marked a new career-high for the third-year linebacker, who has logged double-digit tackles in three straight contests and five of his last six appearances. Through 15 games this season, all starts, Campbell has piled up a career-best 159 tackles (83 solo), including 5.0 sacks, three pass breakups, three forced fumbles and two fumble recoveries on 99 percent of the defensive snaps.
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Lions' Amik Robertson: Still dealing with hand injury
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Robertson (hand) was listed as a limited participant on Monday's estimated practice report.
Robertson was able to play through a hand injury during the Lions' 29-24 loss to the Steelers on Sunday, when he logged four tackles (two solo) while playing in just 27 of 74 defensive snaps (36.5 percent). He'll have two more opportunities to increase his practice participation and avoid an injury designation for Thursday's game against the Vikings.
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Lions' Al-Quadin Muhammad: Limited to open week
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Muhammad (abdomen) was a limited participant in Monday's walkthrough practice.
Muhammad was one of nine Lions players to be limited in the first session of Week 17 prep. He may have sustained an abdominal injury during Sunday's loss to Pittsburgh, when he played 30 of 74 defensive snaps (40.5 percent) without showing up on the box score otherwise. The veteran defensive end will need to log a full practice over the next two days in order to avoid an injury designation for Thursday's Christmas Day tilt against the Vikings.
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Lions' Alim McNeill: Working through abdominal injury
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McNeill (abdomen) was a limited participant in Monday's walkthrough practice.
McNeill played 56 of 74 defensive snaps (76.7 percent) and logged two tackles (one solo) during the Lions' 29-24 loss to the Steelers on Sunday. He appears to have come out of that game with an injury, though his ability to practice in a limited capacity Monday indicates that the issue isn't considered serious. McNeill will have two more chances to increase his practice participation heading into the Lions' Christmas Day tilt against the Vikings on Thursday.