Silatolu was placed on injured reserve Friday with a knee injury, Max Henson of the Panthers' official site reports.
Silatolu has seen action in six games this season as a reserve offensive lineman, and his season comes to a premature end Friday. The Panthers interior line depth has taken a hit recently, as Brendan Mahon (concussion) also landed on injured reserve Thursday.
Silatolu (knee) is listed as questionable for Sunday's season opener against the Cowboys, David Newton of ESPN.com reports.
Silatolu returned to practice in a limited capacity this week after undergoing surgery to repair a torn meniscus in early August. Brendan Mahon could see starting reps at left guard should Silatolu be unable to play.
Silatolu (knee) returned to practice Sunday, Steve Reed of the Associated Press reports.
Silatolu is on the mend from a torn meniscus he sustained in early August. While there's no timeline for his return to game action, the offensive lineman at least appears to be trending in the right direction.
Silatolu tore his meniscus during Tuesday's practice and will undergo surgery Friday, Bill Voth of the Panthers' official site reports.
Silatolu was lined up to be the starting left guard in Carolina, but now he'll be considered week-to-week during recovery. His injury is another blow to the Panthers' offensive front, which saw starting right tackle Daryl Williams suffer a dislocated patella and torn MCL earlier in camp.
The Panthers signed Silatolu to a one-year contract Monday.
Silatolu saw action in 14 games with the Panthers in 2017, starting in three of them in place of Trai Turner at right guard. The 29-year-old is likely to serve in a reserve role for Carolina's offensive line again next season.
Silatolu signed a one-year contract Friday with the Panthers.
Silatolu, who was originally drafted by the Panthers in 2012, was released by the Bears prior to the start of the 2016 season and ended up not playing for any team last year. He'll provide depth for an offensive line that struggled a bit last season after a strong 2015 campaign.
The Panthers have listed Frank Alexander, James Dockery, David Foucault, A.J. Klein, Robert Lester, Star Lotulelei and Amini Silatolu as inactive against the Seahawks.
Lotulelei was the only player ruled out prior to Saturday. Klein was listed as questionable coming into the game due to an ankle issue. The other five players listed as considered healthy scratches.
Panthers starting defensive back Thomas DeCoud is inactive for Saturday's game against the Cardinals after battling a hamstring injury all week.
DeCoud, who has 50 total tackles in 15 games with one interception, was considered doubtful on the team's final injury report of the week.
Other inactives for Carolina include: James Dockery , A.J. Klein, Kyle Love , David Foucault, Amini Siatolu and Frank Alexander.
The Panthers are 5 1/2-point favorites heading into the matchup.
The Panthers have ruled the following players as inactive for Week 17 against Atlanta: cornerback James Dockery. tackle David Foucault, linebacker A.J. Klein, safety Robert Lester, defensive tackle Kyle Love, guard Amini Silatolu, and running back DeAngelo Williams.
Williams was listed as probable heading into Sunday's game with a hand injury. Coach Ron Rivera chose to keep him inactive and roll with the hot hand, Jonathan Stewart, in the starting lineup. If Carolina wins on Sunday, Williams can return to action in the postseason.
A trio of Panthers that had been deemed questionable for the Sunday game against the visiting Browns have been ruled out, including running back DeAngelo Williams (hand). The others are guard Amini Silatolu and linebacker A.J. Klein, both with knee ailments.
The Panthers have listed seven players on its final injury report for Week 16 against Cleveland, four of which were deemed questionable. Those four include linebacker A.J. Klein (ankle), guard Amini Silatolu (knee), running back DeAngelo Williams (hand) and cornerback Carrington Byndom (hamstring).
Meanwhile, safety Roman Harper (thigh), quarterback Cam Newton (back) and linebacker Thomas Davis (knee) were listed as probable.
Panthers quarterback Cam Newton, defensive back James Dockery, running back DeAngelo Williams, safety Robert Lester, tackle David Foucault, guard Amini Silatolu and defensive tackle Micanor Regis were ruled inactive Week 15 against the Bucs.
The Panthers have ruled out quarterback Cam Newton (back) and guard Amini Silatolu (knee) for Week 14 against Tampa Bay. Running back DeAngelo Williams (hand) was the only player on Carolina's final injury report ruled doubtful for the game.
The following players were deemed as probable: Wide receiver Philly Brown (shoulder), cornerback Carrington Byndom (illness), center Ryan Kalil (rest), linebacker A.J. Klein (knee), tight end Greg Olsen (knee), guard Chris Scott (foot), guard Amini Silatolu (knee) and running back Jonathan Stewart (hip).
Panthers were without running back DeAngelo Williams (hand) and guards Amini Silatolu (knee) and Chris Scott (unknown). Tackle Ryan Kalil was also given the day off.
Williams, who had a brace on his hand last week to deal with a broken bone, still has not practiced. He has 219 yards on 68 carries in 2014.
Only two injured players are on the inactive list posted by the Panthers for their Week 14 clash against the Saints. They are running back DeAngelo Williams (hand) and guard Amini Silatolu (knee).
The healthy scratches are cornerback James Dockery, safety Robert Lester, linebacker Horace Miller, tackle David Foucault and defensive tackle Micanor Regis.
The Panthers released their final injury report Friday and listed tight end Greg Olsen (knee) as questionable for Sunday’s game at New Orleans.
The following players are listed as probable: DT Star Lotulelei, DE Mario Addison, C Ryan Kalil and DE Kony Ealy. Amini Silatolu (knee) is listed as out.
The Panthers announced defensive back James Dockery, tackle David Foucault, safety Robert Lester, defensive tackle Star Lotulelei, offensive lineman Amini Silatolu, defensinve tackle Micanor Regis and quarterback Joe Webb are inactive for Week 13 against the Colts.
The Panthers have ruled out defensive tackle Star Lotulelei (ankle) and guard Amini Silatolu (knee) for their Sunday game against Minnesota. Both had been deemed questionable on Friday.
The Panthers unveiled its final injury report for Week 13 against Minnesota. Star Lotulelei (ankle) and Amini Silatolu (knee) were the only two players on the list labeled as questionable. Charles Johnson is battling flu-like symptoms and was ruled as questionable.
Meanwhile, the following four players were designated as probable for Sunday: Bene Benwikere (ankle), Philly Brown (illness), Andrew Norwell (thigh) and Mike Tolbert (knee).
With Panthers offensive tackle Nate Chandler out for the season, ESPN.com reported guard Amini Silatolu has begun working at offensive tackle. Silatolu has started seven games for the Panthers at guard this season.
After giving up nine sacks against Atlanta, the Panthers are trying to find players that can work together at various positions.