W: H. Okajima (4-3) L: P. Coke (6-2)
Miguel Cabrera (26) 2 run shot to left off Matsuzaka, Rhymes scored.
Santiago singled to center, Frazier scored, Laird to second.
Santiago doubled to left, Frazier scored.
Kalish singled to right, Beltre scored.
McDonald doubled to left, Kalish scored.
Ortiz doubled to deep center, McDonald, Lowrie and Youkilis scored.