ST. LOUIS -- Tony La Russa is more concerned with getting ready for the playoffs than winning 100 games.
A victory Sunday in the final regular-season game at Busch Stadium would give the Cardinals back-to-back 100-win seasons for the first time since 1942-44, the only time the franchise accomplished the feat.
"It's not the reason we come out," La Russa said. "We need to play one more really good game and get ready for next week."
Though limited to 99 games because of a herniated disc in his neck, Walker has 15 homers and 52 RBI. It was his 31st career multihomer game and his third this season. He also hit two homers off Ortiz here on June 29.
"I can't get this guy out," Ortiz said. "That's baseball and that's what happens sometimes. I'd like to figure this guy out."
St. Louis has clinched baseball's best record and came into the final series needing a sweep of the Reds to reach 100 wins. The Cardinals move to a new ballpark next season.
"I think because of the history of this franchise, it would be a nice mark for the two-year run," La Russa said. "But any time you chase a number, you're making a big mistake."
Pujols noted that last season's 105 wins did the Cardinals no good in getting swept in the World Series.
"They don't talk about us winning 105 games last year, they talk about Boston, the world champion," he said.
Pujols had a 61 at-bat homerless streak before hitting a grand slam in the seventh inning Friday. He has seven RBI the past two games and scored three times Saturday. He leads the National League with 129 runs.
Cardinals starter Jason Marquis took a 4-0 lead into the fifth, but couldn't hold it.
Marquis walked Kearns with two outs in the sixth, and Edwin Encarnacion hit a two-run homer, his ninth, to put the Reds ahead. If Encarnacion homers Sunday, he'll become the 10th Reds player in double digits.
The Cardinals reclaimed the lead in the bottom of the sixth, helped by Ortiz's wildness. With one out, he walked Pujols, Walker and Reggie Sanders. Mark Grudzielanek singled home a run, and Walker raced home on a short fly to right by So Taguchi.
After Lopez homered to tie it in the seventh, another bout of wildness put St. Louis back on top.
Reliever Allan Simpson (0-1) walked pinch-hitter Skip Schumaker and Abraham Nunez, then hit Pujols to load the bases. Pujols stepped toward the mound -- La Russa quickly rushed out to grab him -- but said he was only asking Simpson what he said. Simpson, according to Pujols, told Pujols he did not intend to hit him.
Marquis allowed five runs and seven hits in six innings. Ortiz pitched six innings and allowed six runs.
- With one game remaining, the Cardinals have drawn a record 3,488,554 fans.
- Unless Brandon Claussen pitches a complete game Sunday, the Reds will tie the team record for fewest complete games with two. Cincinnati also had just two complete games in 2001 and 2002.
- Longtime Cardinals second baseman and manager Red Schoendienst removed the number 2 in the countdown of games remaining at Busch Stadium. Ozzie Smith will remove the number 1 during Sunday's regular-season finale.