"It's fun to watch," Wells said of Rios. "He's coming into his own. He's figuring out what he's capable of doing. I'm proud of him. He's working hard and it's paying off."
Rios is platooning with Eric Hinske in right field, but he's making it hard for Blue Jays manager John Gibbons to keep him on the bench.
Rios went 3-for-4 with a walk, raising his average to .396. He didn't hit his sixth home run last year until August 8. He finished with 10 after hitting just one in his rookie season.
The Blue Jays finished with 13 hits.
"This is fun to be a part of. Everybody is swinging the bat really well," Wells said.
Rios also was credited with a stolen base in the eighth despite almost being picked off first. Wells followed Rios' steal with his ninth homer of the season, giving Toronto a 8-2 lead. The Blue Jays have won four of five.
Wells went 3-for-5, raising his average to .400. He has three multihomer games this season and 12 in his career.
Wells' nine home runs are a career high for a month.
"Hopefully, this is just the start," said Wells, who has struggled in April in past years.
Jeff Conine homered for the Orioles, who have lost four in a row.
Toronto starter Ted Lilly (2-1) became the third consecutive left-hander to beat Baltimore. Lilly allowed two runs and six hits, while striking out three and walking two in five innings.
"We are pretty hot. We're definitely a team I wouldn't want to face as a pitcher," Lilly said. "I'm surprised when we don't get two or three runners on in an inning."
Bedard (4-1) failed to become the majors' first five-game winner. The left-hander gave up five runs and 10 hits in 5 2/3 innings.
"I left a lot of pitches down the middle of the plate," Bedard said. "They are a good team and they hit them."
Jay Gibbons' RBI single gave Baltimore a 1-0 lead in the first, but Toronto scored three runs in the second on shortstop Miguel Tejada's throwing error, John McDonald's RBI double and Reed Johnson's run-scoring grounder.
Conine hit a solo shot in the fifth, his third homer of the season.
After Rios hit his towering homer into the second deck in left in the sixth, Wells hit one over the center-field wall. Toronto has hit consecutive home runs three times this season.
Toronto manager John Gibbons said RHP Casey Janssen will replace injured RHP A.J. Burnett in the rotation on Thursday. Janssen went 1-2 with a 4.05 ERA in four starts at Triple-A Syracuse.