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John McDonald hit a three-homer for Arizona, while Gerardo Parra was 4-for-4 with a double, a walk and two runs. Parra also made a terrific grab running toward the wall in center of Norichika Aoki's deep fly ball in the ninth inning. Parra's four hits tied a career best.
Greinke (5-2), who had allowed one run total in his previous three starts, gave up seven runs and a season-high 10 hits in 2 1/3 innings.
Miley (6-1) gave up five runs -- three earned -- and eight hits in six innings for the victory. He finished with three scoreless innings after a shaky start, winning his third in a row.
"It's all about a team win," Miley said. "We've been struggling and we're just trying to turn it around."
Arizona won at home for only the third time in 13 games.
Miley, in winning his third straight appearance, finished with three scoreless innings after a shaky start. He also doubled and singled, improving his batting average to .444 (8 for 18).
Brad Ziegler and David Hernandez each pitched a hitless inning of relief before J.J. Putz, on his bobblehead night, pitched a perfect ninth for his 10th save in 13 tries - surviving a pair of deep fly balls,
Cody Ransom, claimed by Milwaukee off waivers from Arizona on Wednesday, doubled in two runs. Aoki tripled and doubled for the Brewers.The Diamondbacks had 15 hits, two apiece by McDonald, Aaron Hill, Justin Upton, Jason Kubel and Miley.
Milwaukee, aided by third baseman Ryan Roberts' throwing error, scored four times in the third to go up 5-2.
Greinke, who was 4-0 in his previous six starts and hadn't lost since his second outing on April 12, never made it through the bottom half as Arizona scored five times.
"The third inning it really caught up to me, trying to be real nasty and walked some guys," he said, "trying to be better than I could really pitch. That is the main thing. I got out of my normal game plan."
Upton and Kubel started the inning with their second singles of the night. Paul Goldschmidt walked to load the bases, then Greinke forced in a run with a walk to Robert. Konrad Schmidt's fielder's choice brought in another run. On an 0-2 count, McDonald lined one just over the wall in left field, a three-run shot that made it 7-5.
"I think it was great, coming back after they scored four in the top," McDonald said. "For us to come back and score five for Wade, get him back out there and get him going. He seemed to take off from there. He seemed to settle in."
Miley singled, Parra walked, and that was it for Greinke in his shortest outing since he went two innings in a 12-2 loss at the Yankees last July 28. Greinke walked three and struck out three, allowing 13 baserunners in his brief performance.
"You get any pitcher in an extended inning, where you've got to throw a lot of pitches, and get guys on and get pressure on him, then you've got a chance to get to him," Diamondbacks manager Kirk Gibson said, "and we got to him tonight."
Arizona added a run in the seventh when Parra doubled and scored on Hill's two-out single.
Milwaukee scored in the first on Corey Hart's leadoff double and Jonathan Lucroy's two-out RBI single. Arizona responded with two in the bottom half when Parra, Hill, Upton and Kubel singled, all with no outs.
Before the game, the Diamondbacks announced catcher Miguel Montero had signed a $60 million, five-year contract covering 2013-17. Montero missed his fourth game in a row with a groin strain.
|Zack Greinke gives up seven runs and a season-high 10 hits in just 2 2/3 innings of work. (AP)|
|Players of the Game|
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|Corey Hart, 1B||5||1||1||0||0||1||1||.262|
|Norichika Aoki, RF||5||1||2||0||0||0||1||.304|
|Ryan Braun, LF||5||0||0||1||0||0||2||.312|
|Jonathan Lucroy, C||4||1||2||1||0||1||1||.348|
|Rickie Weeks, 2B||2||1||0||0||2||1||0||.155|
|Cody Ransom, 3B-SS||4||1||1||2||0||3||2||.276|
|Carlos Gomez, CF||3||0||1||0||1||0||1||.258|
|Edwin Maysonet, SS||3||0||1||0||0||0||1||.167|
|a- Taylor Green, PH-3B||1||0||0||0||0||0||1||.188|
|Zack Greinke, P||2||0||0||0||0||0||2||.190|
|Mike McClendon, P||0||0||0||0||0||0||0||.000|
|b- Nyjer Morgan, PH||1||0||0||0||0||0||0||.229|
|Tim Dillard, P||0||0||0||0||0||0||0||.000|
|c- George Kottaras, PH||1||0||0||0||0||1||1||.244|
|Juan Perez, P||0||0||0||0||0||0||0||.000|
|a-flied out for Maysonet in the 8th|
|b-flied out for McClendon in the 6th|
|c-struck out for Dillard in the 8th|
|2B - Corey Hart (14, Miley), Norichika Aoki (5, Miley), Jonathan Lucroy (10, Miley), Cody Ransom (5, Miley), Carlos Gomez (4, Miley)|
|3B - Norichika Aoki (3, Miley)|
|RBI - Ryan Braun (34), Jonathan Lucroy (30), Cody Ransom 2 (15)|
|2-OUT RBI - Jonathan Lucroy (21)|
|Team LOB - 7|
|DP - Maysonet-Hart|
|Zack Greinke (L,5-2)||2.1||10||7||7||3||3||1||3.66|
|HBP - Upton (by Mike McClendon)|
|Pitches-Strikes - Zack Greinke 69-42, Mike McClendon 31-23, Tim Dillard 39-25, Juan Perez 15-11|
|Ground Balls-Fly Balls - Zack Greinke 3-0, Mike McClendon 5-1, Tim Dillard 2-2|
|Batters Faced - Zack Greinke 19, Mike McClendon 11, Tim Dillard 9, Juan Perez 3|
|Gerardo Parra, CF||4||2||4||0||1||0||0||.267|
|Aaron Hill, 2B||5||1||2||1||0||0||2||.258|
|Justin Upton, RF||4||1||2||1||0||0||2||.261|
|Jason Kubel, LF||5||1||2||1||0||1||3||.292|
|Paul Goldschmidt, 1B||4||1||1||0||1||2||2||.248|
|Ryan Roberts, 3B||3||0||0||1||2||3||3||.226|
|Konrad Schmidt, C||4||1||0||1||0||2||4||.000|
|John McDonald, SS||4||1||2||3||0||0||1||.317|
|Wade Miley, P||2||0||2||0||0||0||0||.444|
|Brad Ziegler, P||0||0||0||0||0||0||0||.000|
|a- Josh Bell, PH||1||0||0||0||0||1||0||.167|
|David Hernandez, P||0||0||0||0||0||0||0||.000|
|J.J. Putz, P||0||0||0||0||0||0||0||.000|
|a-struck out for Ziegler in the 7th|
|2B - Gerardo Parra (9, Dillard), Paul Goldschmidt (11, McClendon), Wade Miley (1, McClendon)|
|HR - John McDonald (2, Greinke)|
|SH - Wade Miley (3)|
|RBI - Aaron Hill (18), Justin Upton (19), Jason Kubel (22), Ryan Roberts (20), Konrad Schmidt (1), John McDonald 3 (8)|
|2-OUT RBI - Aaron Hill (4)|
|CS - Gerardo Parra (3, 2nd base by Greinke/Lucroy)|
|Team LOB - 10|
|PB - Konrad Schmidt (1)|
|E - Ryan Roberts (7, Throwing)|
|Wade Miley (W,6-1)||6||8||5||3||2||2||0||2.41|
|Brad Ziegler (H,3)||1||0||0||0||0||2||0||2.33|
|David Hernandez (H,8)||1||0||0||0||1||2||0||2.14|
|J.J. Putz (S,10)||1||0||0||0||0||1||0||6.75|
|WP - Wade Miley 2 (2)|
|Pitches-Strikes - Wade Miley 108-63, Brad Ziegler 9-7, David Hernandez 17-10, J.J. Putz 11-8|
|Ground Balls-Fly Balls - Wade Miley 5-12, Brad Ziegler 1-0|
|Batters Faced - Wade Miley 29, Brad Ziegler 3, David Hernandez 4, J.J. Putz 3|
|Attendance - 30184|
|Game Time - 2:59|
|Temperature - 80|
|Umpires - Home - Derryl Cousins, First Base - Bill Miller, Second Base - Ron Kulpa, Third Base - D.J. Reyburn|