| Passing | ||||
| CP/AT | YDS | TD | INT | |
| Roethlisberger | 25/44 | 330 | 0 | 3 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| R. Mendenhall | 15 | 64 | 0 | 11 |
| M. Moore | 1 | 21 | 0 | 21 |
| Roethlisberger | 1 | 0 | 0 | 0 |
| I. Redman | 2 | -1 | 0 | 0 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| J. Cotchery | 5 | 93 | 0 | 36 |
| H. Miller | 5 | 82 | 0 | 39 |
| M. Wallace | 5 | 66 | 0 | 36 |
| A. Brown | 5 | 59 | 0 | 24 |
| R. Mendenhall | 3 | 25 | 0 | 13 |
| M. Moore | 2 | 5 | 0 | 7 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| Roethlisberger | 2 | 1 | 1 | -10 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| S. Suisham | 1/2 | 51 | 0/0 | 3 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| J. Kapinos | 4 | 38.5 | 1 | 42 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| A. Brown | 3 | 28.3 | 0 | 36 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| A. Brown | 2 | -5.0 | 0 | 0 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| T. Polamalu | 7-0 | 0.0 | 0 | 0 |
| L. Timmons | 6-0 | 0.0 | 0 | 0 |
| R. Clark | 5-0 | 0.0 | 0 | 0 |
| J. Worilds | 5-1 | 0.0 | 0 | 0 |
| Z. Hood | 4-1 | 0.0 | 0 | 0 |
| J. Farrior | 4-0 | 0.0 | 0 | 0 |
| I. Taylor | 2-0 | 0.0 | 0 | 0 |
| L. Woodley | 2-0 | 0.0 | 0 | 0 |
| K. Lewis | 2-0 | 0.0 | 0 | 0 |
| W. Gay | 2-1 | 0.0 | 0 | 0 |
| R. Foster | 1-0 | 0.0 | 0 | 0 |
| S. Sylvester | 1-0 | 0.0 | 0 | 0 |
| C. Allen | 1-0 | 0.0 | 0 | 0 |
| M. Starks | 1-0 | 0.0 | 0 | 0 |
| C. Hampton | 1-0 | 0.0 | 0 | 0 |
| J. Cotchery | 1-0 | 0.0 | 0 | 0 |
| M. Wallace | 1-0 | 0.0 | 0 | 0 |
| D. Cromartie-Smith | 1-0 | 0.0 | 0 | 0 |
| L. Foote | 1-0 | 0.0 | 0 | 0 |
| B. Keisel | 0-1 | 0.0 | 0 | 0 |
| 1 | 2 | 3 | 4 | |
| Pittsburgh | 0 | 0 | 3 | 0 |
| San Francisco | 3 | 3 | 7 | 7 |
| 4th Quarter | |
| 1-10-SF 2 | (3:17) A.Dixon up the middle to SF 5 for 3 yards (Z.Hood). |
| 2-7-SF 5 | (3:11) A.Dixon right guard to SF 9 for 4 yards (J.Farrior, Z.Hood). |
| 3-3-SF 9 | (2:26) A.Dixon right tackle to SF 11 for 2 yards (Z.Hood). |
| 4-1-SF 11 | (2:17) A.Lee punts 57 yards to PIT 32, Center-B.Jennings. A.Brown to PIT 22 for -10 yards (T.Gooden). PENALTY on PIT, Illegal Block Above the Waist, 10 yards, enforced at PIT 22. |
| 1-10-PIT 12 | (2:01) (Shotgun) B.Roethlisberger pass short right to J.Cotchery to PIT 21 for 9 yards (C.Rogers). |
| 2-1-PIT 21 | (1:56) (Shotgun) B.Roethlisberger pass incomplete short right to M.Wallace. |
| 3-1-PIT 11 | (1:50) (Shotgun) B.Roethlisberger FUMBLES (Aborted) at PIT 21, and recovers at PIT 11. B.Roethlisberger to PIT 11 for no gain (A.Brooks). B.Roethlisberger credited with rush of 0-yds. |
| 4-11-PIT 11 | (1:11) J.Kapinos punts 39 yards to 50, Center-G.Warren, fair catch by K.Williams. |
| 1-10-50 | (1:09) Alex Smith kneels to SF 49 for -1 yards. |
| 2-11-SF 49 | (:36) Alex Smith kneels to SF 48 for -1 yards. |
| Passing | ||||
| CP/AT | YDS | TD | INT | |
| A. Smith | 18/31 | 187 | 1 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| F. Gore | 18 | 65 | 1 | 13 |
| A. Dixon | 5 | 12 | 0 | 4 |
| A. Smith | 3 | 12 | 0 | 14 |
| T. Ginn | 1 | 6 | 0 | 6 |
| B. Miller | 1 | 3 | 0 | 3 |
| K. Hunter | 2 | 2 | 0 | 2 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| V. Davis | 6 | 72 | 1 | 31 |
| M. Crabtree | 4 | 35 | 0 | 12 |
| K. Williams | 4 | 33 | 0 | 10 |
| K. Hunter | 2 | 24 | 0 | 27 |
| T. Ginn | 1 | 14 | 0 | 14 |
| B. Swain | 1 | 9 | 0 | 9 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| J. Smith | 0 | 0 | 1 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| D. Akers | 2/2 | 38 | 2/2 | 8 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| A. Lee | 6 | 47.5 | 4 | 62 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| T. Ginn | 1 | 12.0 | 0 | 12 |
| K. Williams | 1 | 18.0 | 0 | 18 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| Defense | ||||
| T-A | SCK | INT | FF | |
| N. Bowman | 7-1 | 0.0 | 0 | 0 |
| D. Goldson | 6-1 | 0.0 | 1 | 0 |
| C. Culliver | 5-0 | 0.0 | 0 | 0 |
| L. Grant | 4-1 | 0.0 | 0 | 0 |
| A. Brooks | 4-2 | 0.0 | 0 | 0 |
| P. Haralson | 3-0 | 0.0 | 0 | 0 |
| D. Whitner | 3-0 | 0.0 | 0 | 0 |
| J. Smith | 3-0 | 0.0 | 0 | 0 |
| A. Smith | 3-1 | 2.5 | 0 | 0 |
| C. Rogers | 2-0 | 0.0 | 1 | 0 |
| C. Spillman | 2-0 | 0.0 | 0 | 0 |
| I. Sopoaga | 2-0 | 0.0 | 0 | 0 |
| T. Gooden | 2-0 | 0.0 | 0 | 0 |
| R. Smith | 1-0 | 0.0 | 0 | 0 |
| R. McDonald | 1-1 | 0.5 | 0 | 1 |
| M. Williams | 1-0 | 0.0 | 0 | 0 |
| D. Walker | 1-0 | 0.0 | 0 | 0 |
| S. Spencer | 1-0 | 0.0 | 0 | 0 |
| T. Brown | 0-0 | 0.0 | 1 | 0 |
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