Cromartie (ankle) is considered questionable for Sunday's game against the Seahawks.
Cromartie's ankle injury kept him out of the 49ers' Week 2 loss to the Panthers, and he was limited in practice throughout the week leading up to this Sunday's matchup. Eric Reid will be the starter at free safety regardless, but Cromartie will look to get back to game action.
Lynch has been suspended for the first four games of the regular season for violating the league's substance abuse policy.
Lynch slid to the fifth round of the 2014 Draft amid character concerns, but developed into of the league's best young outside linebackers by totaling 12.5 sacks over his first two seasons. Nonetheless, Lynch has now incurred his first NFL off-field slip-up, and will miss the first quarter of the regular season as a consequence. With Lynch suspended until San Francisco's Week 5 game against the Cardinals, Eli Harold and Corey Lemonier are candidates to start opposite Ahmad Brooks in the meantime.
Bethel (foot) practiced in full Wednesday, Darren Urban of the Cardinals' official site reports.
Bethel has endured a slow recovery from offseason foot surgery, which is expected to impact him throughout the campaign. Active status in Week 1 equated to 22 snaps on special teams and none on defense, but perhaps Wednesday's full showing will open the door to work in the defensive backfield. After rookie corner Brandon Williams was torched by the Patriots on Sunday, Bethel is the prime candidate to make a run at the starting job opposite Patrick Peterson, pending his health, of course.
Nkemdiche (ankle) is considered questionable for Sunday's tilt against the Bills, Mike Jurecki of Fox Sports reports.
Nkemdiche was ruled out of the Cardinals' Week 2 win over the Buccaneers after aggravating his ankle injury, and it could be severe enough to keep him out once again Sunday. If he's able to play, he'll look to make his first tackle of the season.