Can Big Ben and the Steelers keep pace with the division-leading Bengals? They'll have to get past the Seahawks -- in Seattle. Will Brock Osweiler give the Broncos a fighting chance against the 10-0 Patriots?
Seattle's secondary, once known for ferocious hits and turnovers, isn't the same unit we're accustomed to seeing. What's especially disturbing is they have struggled against the top passers. A closer look at the tapes reveals what's wrong with the Seahawks.
Johnson (thigh) is listed as questionable for Sunday's game in Cincinnati, Nick Wagoner of ESPN.com reports.
If Johnson isn't able to play, LaMarcus Joyner and Marcus Roberson will likely take on additional snaps. It would be a tough break for the Rams, though none of the bunch warrants serious IDP considerations.
Keenum (concussion) is listed as questionable for Sunday's game in Cincinnati, Nick Wagoner of ESPN.com reports.
According to Wagoner, the Rams are preparing for Nick Foles to start, as Keenum still hasn't cleared the NFL's concussion protocol. However, there is some chance Keenum will be cleared by Sunday, in which case he'd likely have the opportunity to redeem himself from a disastrous Week 11 showing.
Quinn (hip) is listed as questionable for Sunday's game in Cincinnati, Nick Wagoner of ESPN.com reports.
Quinn missed a Week 11 game in Baltimore and hasn't handled a full snap count since Week 5. His presence, even in a limited capacity, would likely be useful to the Rams, but there's no shortage of superior IDP options.
Bailey has been suspended four games for violating the NFL Policy and Program for Substances of Abuse.
With Bailey -- who has recorded 12 catches for 182 yards and a touchdown in eight game to date -- set to miss time, it's now understandable that the Rams are expected to work out wideouts Hakeem Nicks, Wes Welker and Vincent Brown, per ESPN's Adam Caplan.
Boldin (hamstring) hauled in five of seven targets for 93 yards in Sunday's 29-13 loss at Seattle.
It was a brutal matchup for Boldin and he didn't appear to be 100 percent, looking gimpy on some routes. He also spent a little time on the bench in the first half, while the 49ers had the ball, warming up his tender hamstring. However, he made a number of tough grabs in traffic, and seemed to have a solid rapport with Blaine Gabbert, who did a nice job in the loss, completing 22 of 34 passes for 264 yards and a touchdown. Assuming Boldin made it out of Sunday's game without any setback, he'll have another tough matchup in Week 12 against the Cardinals.
Bowman (shoulder) had a relatively quiet game by his standards, recording nine tackles (four solo) in the 29-13 loss to the Seahawks.
Bowman continues to pop up on the injury report for a minor shoulder injury, but it didn't seem to affect the veteran linebacker as he was on the field for all 78 of the team's defensive snaps. With the opposition running the ball 44 times, you would think Bowman would have notched more than nine tackles, but Thomas Rawls was getting into the secondary consistently which did not benefit Bowman. A matchup against the Cardinals' potent air attack looms next week, so the tackle totals could be held in check for Bowman yet again.
Brooks (personal) returned to the field Thursday, recording five tackles (two solo) and a pair of sacks in the loss to Seattle.
Brooks had missed last week's contest to attend the funeral of his sister. He returned Thursday and the extra rest seemed to have given the veteran linebacker a boost. While this was a monster game, it has to be taken with a grain of salt, as the Seattle offensive line is, well, offensive.
Hyde (foot) has been ruled out for Sunday's game against the Cardinals, CSN Bay Area reports.
Hyde still hasn't played since Week 7 and is no lock to suit up again this season. Shaun Draughn will continue to lead the San Francisco backfield, with Kendall Gaskins and Travaris Cadet working in reserve. Draughn played nearly all of the offensive snaps in Week 11 against the Seahawks.
Antoine Bethea is set to start for the 49ers this season at strong safety with Eric Reid entrenched at free safety. But the former doesn't know who their secondary mates will be and he's expecting quite a battle.
Tartt finished with eight tackles (four solo) in Sunday's loss to Seattle.
Tartt has been starting at strong safety ever since Antoine Bethea (shoulder) was shut down for the season. He has been averaging 6.0 tackles in the those three starts. He doesn't seem like the type of player that will haul in too many interceptions, but his size and athleticism give him a little upside in IDP leagues for tackles, forced fumbles, and the occasional sack.
Smelter (knee) is slated to practice this week, the San Jose Mercury News reports.
Smelter will remain on the 49ers' Reserve/Non-Football Injury list for now, as the team has a three-week window in which to evaluate whether or not to officially add the wideout to the team's 53-man active roster.