Wentz (ribs) will not play in Saturday's matchup with the Colts.
Wentz suffered a hairline rib fracture in the preseason opener and hasn't taken the field since. His final chance to return will be on Sept. 1 in the final preseason game against the Jets. With Wentz out, Sam Bradford has cemented his role as the Eagles' starting quarterback this preseason and should see a majority of the reps on Saturday night.
Matthews, who suffered a bone bruise on his left knee back on Aug. 5, plans to be ready to play in advance of Week 1, the Philadelphia Inquirer reports. "I promise you I'll be ready for the first game," Matthews declared Tuesday. "I don't like to put percentages on anything, but at the same time, I'm definitely feeling good. I'm doing a lot better. I'm running around, moving, lifting, jumping. I'm back doing pretty much all of that stuff."
Matthews, who is coming off a 2015 campaign in which he caught 85 passes for 997 yards and eight touchdowns, doesn't seem likely to see any preseason action, but the goal here is exercise a degree of patience and caution, with having the wideout available for the Eagles' Sept. 11 contest against the Browns. Upon his return to action, Matthews is set to serve as the team's top wideout, with Nelson Agholor, Dorial Green-Beckham, Rueben Randle, Josh Huff, Chris Givens and Paul Turner all still jostling for slotting on Philadelphia's wideout depth chart.
Smallwood (quadriceps) is slated to take the field for Saturday's preseason game at Indianapolis, Jeff McLane of the Philadelphia Inquirer reports.
Smallwood missed back-to-back contests to kick off exhibition season, but increasing his workload little by little for two weeks will seemingly yield an appearance Saturday. A cautious approach is expected, though, as the running back's quad continues to heal. All but guaranteed a roster spot due to his status as a 2016 fifth-round selection, he could be relegated to weekly inactives in-season with Ryan Mathews, Darren Sproles, and Kenjon Barner all positioned ahead of Smallwood on the depth chart.
Nelson (knee) is inactive for Friday's preseason matchup with the 49ers.
Nelson resumed practicing earlier this week, but he is not ready for game action just yet. With just one preseason game remaining, it's looking likely that Nelson will not play at all during the exhibition season. Both he and the Packers have indicated Nelson will be ready to go by Week 1, but his snaps could be limited a bit early on as he gets himself back into game shape.
Janis (hand) had surgery on his fractured hand and will be out for at least 4-6 weeks, Rob Demovsky of ESPN reports.
Janis fractured his hand during Friday's preseason opener against the Browns and was originally considered week-to-week. Now that he's been ruled out for at least a month, it'll be tough for him to survive the final roster cuts heading into the regular season. Along with Jared Abbrederis and Trevor Davis, Janis was competing for the final spot or two on the receiver depth chart in Green Bay, and his injury could wind up being the deciding factor.
Quarless (suspension) signed a deal with the Lions on Monday, Adam Schefter of ESPN reports.
With tight ends Eric Ebron and Brandon Pettigrew both recovering from injuries, the Lions are facing serious depth issues at tight end for this coming season. And while Quarless will still be suspended for the first two games of the regular season, he had a solid stint with the Packers and would be a formidable option for the team should neither Ebron nor Pettigrew be ready by Week 3. He is eligible to start practicing with the team immediately.
Montgomery caught one pass for seven yards on five targets in Thursday's preseason game against Oakland.
Just removed from the PUP list last week, Montgomery has played in both of Green Bay's preseason games, but he only has two catches for 14 yards on eight targets. While likely just competing for the fourth on fifth spot on the depth chart at wideout, the 2015 third-round selection could emerge as an option to return kicks and/or punts. It's also not out of the question that he could eventually push Davante Adams or Jared Abbrederis for playing time at wide receiver.