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The 49ers placed Colbert (ankle) on injured reserve Monday, David Lombardi of The Athletic reports.

Upon further examination, it was determined that Colbert is nursing a right high-ankle sprain. Colbert's timetable for a return is estimated at about 6-to-8 weeks, which prompted San Francisco to put the safety on IR to open up a roster spot. According to the report, Colbert is an unlikely candidate to return this season. All signs point to D.J. Reed taking over as the 49ers' starting free safety with Colbert out of the mix.

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