The Colorado Rockies took two out of three games against the San Francisco Giants at home last weekend, and they will aim for the same success on the road beginning on Friday night. They tied their franchise record for runs in a 20-7 win over Boston on Wednesday, scoring multiple times in each of the first four innings. Colorado is a +158 underdog at San Francisco on Friday in the latest MLB odds from SportsLine consensus. The Giants have lost five of their last seven games, so should you fade them with your MLB parlay bets?
San Francisco is the second-heaviest favorite on Friday's loaded MLB schedule behind the Brewers, who are -235 against the Marlins. The slate also includes Astros (-125) vs. Dodgers, Mets (-135) vs. Braves and Phillies (-170) vs. Guardians. Before making any MLB picks or parlays, be sure to check out the MLB predictions and betting advice from SportsLine's proven simulation model.
The SportsLine Projection Model simulates every MLB game 10,000 times. It entered Week 18 of the 2024 MLB season a profitable 53-44 on all-top rated MLB picks this season. Dating back to last season, it is on a 24-11 roll on top-rated run-line picks (+877). Anybody following has seen strong returns.
For Friday, the model has locked in three MLB best bets for games that begin at 7:10 p.m. ET or later. If you successfully parlay the picks, you'd be looking at a payout of almost 10-1. You can see the model's MLB picks only at SportsLine.
Top MLB picks today
After simulating every game on Friday 10,000 times, the model is picking the Yankees (-120) to beat the Red Sox. New York has dropped four of its last five games, but the Red Sox are in bad form as well. They have lost five of their last six contests, including the 20-7 loss to Colorado on Wednesday.
Left-handed pitcher Nestor Cortes has a 3.99 ERA and will be on the mound for the Yankees, while Red Sox starter Brayan Bello has a 5.27 ERA. Cortes is 2-0 in five career starts against Boston, and he is backed up by some of the league's best power hitters. Aaron Judge and Juan Soto have hit a combined 61 home runs, which is one reason why the model has the Yankees winning in well over 50% of simulations. See the model's top MLB picks here.
How to make Friday MLB parlays
The model also locked in two other MLB best bets for Friday, including backing a large National League underdog. You can see the model's MLB Friday best bets and parlay only at SportsLine.
What MLB picks should you target for a payout of almost 10-1? Visit SportsLine now to see the MLB best bets for Friday from the model that's on a 24-11 run on top-rated MLB run-line picks, and find out.