Tuimoloau is being evaluated for a possible concussion and is questionable to return to Sunday's game against the Jaguars.
Tuimoloau appeared to sustain the injury during kickoff coverage, and he is being evaluated by medical staff to determine whether he can return. With Tyquan Lewis (ankle) inactive, Samson Ebukam would serve as the Colts' lone rotational defensive end behind starters Kwity Paye and Laiatu Latu if Tuimoloau is ruled out.
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Colts' JT Tuimoloau: Healthy for Week 1
Rotowire
Tuimoloau (undisclosed) did not appear on the Colts' injury report Wednesday.
Tuimoloau was nursing an undisclosed injury during the final stretch of the preseason, but he now appears to be back to full health for Week 1. The defensive lineman will likely make his NFL debut as a depth option in Sunday's regular-season opener against Miami.
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Colts' JT Tuimoloau: Exits with undisclosed injury
Rotowire
Tuimoloau left Saturday's preseason loss to Green Bay due to an undisclosed injury, 93.5 FM The Fan Indianapolis reports.
Tuimoloau left the team's first preseason game with a knee injury, so this could be a setback. The 2025 second-rounder is competing for a rotational role at defensive end for the upcoming season.
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Colts' JT Tuimoloau: Colts add standout Round 2 DE
Rotowire
The Colts selected Tuimoloau in the second round of the 2025 NFL Draft, 45th overall.
Tuimoloau (6-foot-4, 265 pounds) is a prototypical three-down defensive end who should prove a viable starter in the NFL. For now, the Ohio State product will likely fill a rotational role, because Kwity Paye and Laiatu Latu will be tough to displace from the starting lineup anytime soon. If Tuimoloau has to play in a DE3 role for the Colts, then he'll likely prove overqualified after torching his way to 21.5 tackles for loss, including 12.5 sacks, last year.