The 2018 MLB season opens Thursday with an AL East matchup between the New York Yankees and Toronto Blue Jays at 3:37 p.m. ET. The Yankees are -150 on the money line, meaning it would take a $150 bet on New York to win to return $100. The over-under for total runs scored is 8.5.

Before you make any kind of pick on this 2018 MLB Opening Day matchup, you need to see what SportsLine's advanced computer has to say.

This model, which simulates every game 10,000 times, finished the 2017 season on a roll, nailing four of its final five top-rated money line picks in the postseason. Anybody who followed it during that stretch cashed in huge.

Now the computer has simulated this division rivalry between the New York Yankees and Toronto Blue Jays 10,000 times and locked in money line, over-under and against-the spread picks.

We can tell you the model likes the Over in 51 percent of simulations. And it also has identified one team as a strong value on the money line, saying they're winning 10 percent more often than their odds would indicate. You can get that top-rated pick only over at SportsLine.

The model knows that the Yankees are a team on the rise, having added NL MVP Giancarlo Stanton this offseason. Stanton dominated at the plate in 2017, producing a career-high in home runs (59), hits (168) and RBIs (132).

The Yankees, who were just one win away from the World Series last year, are expected to be one of the most explosive offensive teams in baseball featuring Stanton and Aaron Judge, the 2017 AL Rookie of the Year.

But just because the Yankees' offense features a dangerous lineup doesn't mean they will be able to go on the road and beat their division rival.

New York is just 5-14 in its last 19 games on the road against the Blue Jays.

So which side should you be all over? Visit SportsLine now to find out which side of the Yankees-Blue Jays money line is a coveted top-rated pick, all from the computer model that simulates every game 10,000 times and nailed four of its last five top-rated MLB money line picks last season.