The Philadelphia 76ers will take on the Orlando Magic at 7 p.m. ET on Wednesday at the Amway Center. Orlando is 3-7 overall and 3-3 at home, while Philadelphia is 7-3 overall and 3-3 on the road. The Sixers are 6-3 against the spread in their last nine meetings against Orlando, while the Magic have won 15 of their last 20 matchups against Philadelphia at home. Orlando is favored by 2.5 points in the latest Magic vs. Sixers odds, while the over-under is set at 206.5. Before locking in any 76ers vs. Magic picks, you'll want to see the NBA predictions from the advanced computer model at SportsLine.

The model simulates every NBA game 10,000 times, and anyone who followed it last season saw massive returns, finishing 300-252 on all its top-rated NBA picks. On top-rated NBA picks against the spread and on the money line alone, the model returned a whopping $4,280 last season. It also entered Week 4 of the 2019-20 NBA season on a 6-2 run on all top-rated NBA picks. Anybody who has followed it has seen huge returns.

Now, it has simulated Magic vs. Sixers 10,000 times and the results are in. We can tell you that the model is leaning over, and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You can only see the pick at SportsLine.

Orlando came up short against Indiana on Sunday, falling 109-102. It was the Magic's fifth loss in their last six games. Evan Fournier led Orlando with 22 points. He is averaging 15.5 points per game, second on the team. Nikola Vucevic, who became the franchise's third all-time leading scorer on Sunday, finished with 18 points and 17 rebounds. 

Meanwhile, Philadelphia narrowly escaped with a win on Tuesday against Cleveland, 98-97. Joel Embiid posted a double-double with 27 points and 16 rebounds. Embiid's dunk with 13.2 seconds left in the game sealed the victory for Philadelphia. It was his fifth double-double of the season so far. Embiid leads the Sixers in points per game with 23.0, and in rebounds with 12.4 per game. Ben Simmons returned from a two-game layoff because of a shoulder injury and scored 15 points against the Cavaliers. However, Embiid and Simmons may both be rested Wednesday in the Sixers' first set of back-to-back games this season. 

The Magic rank fourth in the league when it comes to steals given up per game, with only 6.4 on average. But Philadelphia enters the contest with 10.2 steals per game on average, good for best in the league. 

So who wins Sixers vs. Magic? And which side of the spread hits in over 60 percent of simulations? Visit SportsLine now to find out which side of the Sixers vs. Magic spread you need to jump on Wednesday, all from the model that has crushed its NBA picks, and find out.