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Aaron Rodgers makes his triumphant return to the Jets after lasting only four plays in last year's season-opener. New York opens the 2024 NFL season on the road at defending NFC champion San Francisco on Monday Night Football. The future Hall of Fame quarterback may be 40 years old, but he has plenty to prove to the doubters who think his game will continue to regress. There is plenty to dissect while making NFL score predictions and NFL predictions.

Surrounded by two of the best in the league at their skill positions, Breece Hall at running back and Garrett Wilson at wide receiver, Rodgers has the necessary talent around him to succeed. Will the Jets take the next step and capture the AFC East Division title if Rodgers can stay healthy this season? A win against the 49ers would go a long way. Before you make any Week 1 NFL picks, be sure to see the exact score predictions from SportsLine expert Eric Cohen.

Cohen, a SportsLine NFL expert and host of the Friday NFL props show on SportsLine's YouTube page, evaluated the entire Week 1 NFL slate and delivers score predictions and analysis for each matchup. He finished last season on a 39-28 roll on NFL picks and was profitable for bettors. His exact score predictions were a hit on social media last year and he even hit an exact score in the playoffs, Kansas City's 27-24 upset victory in Buffalo in the AFC Divisional Round. Anyone who followed Cohen's NFL predictions was profitable. You can only see Cohen's Week 1 NFL exact score predictions at SportsLine.

Top Week 1 NFL picks

After diving into all 16 games from the NFL's opening week, Cohen is high on one of those Week 1 home upset picks, the Indianapolis Colts to upset the Houston Texans, 29-26. The Colts now feature one of the best rushing attacks in the NFL with star running back Jonathan Taylor and second year quarterback Anthony Richardson. Richardson played in only four games during his rookie season and rushed for four scores in that time. He and Taylor played together for less than a half after the running back returned from his multi-game contract holdout.

Last year, in a Week 18 matchup for a division title and playoff berth against Houston, Taylor rushed for 188 yards on 30 carries and a touchdown in the Colts' narrow defeat. While the fifth year pro has only played in 21 games over the last two seasons due to injuries and a holdout, he has averaged nearly 4.5 yards per attempt over that time period. Cohen believes this potent combination will succeed against the Houston defense and lead Indianapolis to a 1-0 start. See his other Week 1 football score predictions at SportsLine.

How to make Week 1 NFL score predictions

In addition, Cohen is picking an AFC favorite to dominate its Week 1 opponent by more than three touchdowns. Nailing this result is key to making winning Week 1 NFL picks. You can only see it at SportsLine.

Who wins each Week 1 NFL game, and which AFC team throttles its opponent? Visit SportsLine now to get Eric Cohen's NFL Week 1 score predictions, all from the NFL expert who finished on a 39-28 roll last season.