The Detroit Lions look to bounce back after a shocking home loss as they travel to take on the Arizona Cardinals on Sunday afternoon. Detroit (1-1) fell to Tampa Bay, 20-16, while Arizona (1-1) demolished the Rams at home last Sunday, 41-10. The Lions are 5-0-1 in the last six meetings, including a 30-12 victory the last time the teams met in 2021.
Kickoff from State Farm Stadium is set for 4:25 p.m. ET. Detroit is a 3-point favorite in the latest Cardinals vs. Lions odds per SportsLine consensus, while the over/under for total points is 51.5. Before making any Lions vs. Cardinals picks, you need to see the NFL predictions and betting advice from the proven computer model at SportsLine.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 3 of the 2024 NFL season on an incredible 187-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 41-22 roll on top-rated NFL picks since Week 7 of 2022.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP
Now, the model has set its sights on Lions vs. Cardinals and just locked in its picks and NFL Week 3 predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and betting lines for spread, money line and over/under:
- Lions vs. Cardinals spread: Lions -3
- Lions vs. Cardinals over/under: 51.5 points
- Lions vs. Cardinals money line: Lions -153, Cardinals +129
- Lions vs. Cardinals picks: See picks at SportsLine
Why the Lions can cover
Detroit must bounce back after a surprising home loss to Tampa Bay in Week 2, a game in which quarterback Jared Goff attempted 55 passes, yet threw no touchdowns. Goff only had one touchdown-less performance last season (a 38-6 loss to Baltimore) so it's reasonable to expect a bounce back effort this week. After a quiet Week 1 performance in a win over the Rams, star wide receiver Amon-Ra St. Brown caught 11 passes for 119 yards in the losing effort.
A key for Detroit this week is to re-establish the connection between Goff and second year tight end Sam LaPorta. In two games, has only six catches on eight combined targets for 58 yards. Last year, LaPorta totaled 889 yards and ten scores on 89 catches so look for a breakout from him in the coming weeks. In what is the NFL's highest totaled game of Week 3 per the oddsmakers, expect plenty of success from the Lions passing attack. See which team to pick here.
Why the Cardinals can cover
If Kyler Murray continues to play as well as he has through the season's first two weeks, he may end up being an MVP candidate by season's end. Against Los Angeles, Murray was unstoppable, going 17 of 21 passing for 266 yards and three touchdowns. The Cardinals' quarterback also added 59 yards rushing on five scrambles.
Murray has a host of weapons around him, including rookie first round pick Marvin Harrison Jr., who had four catches for 130 yards and two scores in the team's Week 2 victory. It was quite the bounce back effort after Harrison was held to only one catch by Buffalo in Week 1. Tight end Trey McBride caught six passes for 67 yards, while running back James Conner rushed 21 times for 122 yards and a touchdown last week. See which team to pick here.
How to make Lions vs. Cardinals picks
The model has simulated Lions vs. Cardinals 10,000 times and the results are in. It is leaning Over on the point total, and it also says one side of the spread is the better value. You can only see the model's Lions vs. Cardinals pick at SportsLine.
So who wins Cardinals vs. Lions on Sunday, and which side of the spread is the better value? Visit SportsLine right now to see which side of the Cardinals vs. Lions spread you should be all over Sunday, all from the model on a 187-130 roll on its top-rated NFL picks, and find out.