Brendel has opted out of the 2020 season, Nick Wagoner of ESPN.com reports.
The journeyman center spent time in Dallas, Miami, Denver and Baltimore before signing a contract with the 49ers earlier this year. He is the third member of the 49ers to opt out of the season.
Brendel signed a contract with the 49ers on Monday.
Brendel was cut loose by the Ravens at the end of November, but he'll now get a shot with San Francisco to win a roster spot. He's bounced around since being signed by the Cowboys as an undrafted free agent in 2016, spending time in Dallas, Miami, Denver and Baltimore.
Brendel was cut by the Ravens on Saturday.
Brendel was cut to make room for fellow depth lineman Parker Ehinger, whom Baltimore promoted from the practice squad.
Brendal signed a contract with the Ravens on Wednesday, Daniel Oyefusi of The Baltimore Sun reports.
After Matt Skura was placed on injured reserve with a significant knee injury, the Ravens needed to add depth to their offensive line. Signing Brendel achieves that, but the 27-year-old center isn't expected to feature prominently with Baltimore.
Brendel signed a contract with the Broncos on Thursday, Ryan O'Halloran of The Denver Post reports.
Brendel participated in the team's minicamp this week on a tryout basis and evidently did enough to presumably stick around for the rest of the offseason. He'll compete for a depth role along the offensive line.
Brendel (calf) was placed on injured reserve Wednesday, Adam H. Beasley of the Miami Herald reports.
Brendel spent the first half of the season on injured reserve with an injury to the same calf. The UCLA product sustained this particular injury in practice Dec. 6 and was considered week-to-week afterward. Brendel missed Sunday's divisional tilt with the Patriots and now will miss the remainder of the season.
Brendel (calf) was ruled out for Sunday's game against the Patriots, Joe Schad of The Palm Beach Post reports.
Brendel was added to the injury report Wednesday after injuring the same calf that kept him on injured reserve the first half of the season. Travis Swanson will be called upon at center should he able to play through an ankle injury.
Brendel (calf) suffered a calf injury during Wednesday's practice, Armando Salguero of the Miami Herald reports.
Brendel was a limited participant in Thursday's practice. The starting offensive lineman appears to have injured the same calf which kept him on injured reserve throughout the first eight games of the season. Coach Adam Gase called Brendel week-to-week, indicating that he'll likely miss Sunday's divisional tilt against the Patriots.
Brendel (calf) returned to practice Wednesday, Alain Poupart of the Dolphins' official site reports.
Brendel was placed on injured reserve at the start of the season after the calf injury slowed him throughout training camp and the preseason. Now that he's back practicing again, the 26-year-old will be eligible to return following the Dolphins' Week 8 game against the Texans and must be activated prior to Nov. 8 or else remain on IR for the rest of the season.
Brendel (calf) was placed on injured reserve Monday, Adam Beasley and Barry Jackson of the Miami Herald report.
Brendel has been dealing with a calf injury for almost the entirety of the preseason, but if he can get healthy, there is a chance the Dolphins could activate him after eight games.
Brendel (calf) is not participating in Dolphins practice Monday, Jason Lieser of The Palm Beach Post reports.
Brendel is still not practicing after sustaining a calf injury on the first day of camp. Brendel was expected to be in the mix for the starting role following Mike Pouncey's departure to the Chargers, but his continued absence could secure the spot for Daniel Kilgore.
Brendel signed his restricted free-agent tender Wednesday, Barry Jackson of the Miami Herald reports.
Brendel was a pleasant surprise when the team needed him to step in for an injured Mike Pouncey at center last season. With Pouncey having since signed with the Chargers, Brendel should be in the mix for a starting job in 2018.
Brendel was promoted from the practice squad to the active roster Saturday.
The Dolphins waived cornerback Chris Culliver in a corresponding roster move. Brendel will presumably provide depth at center for the team.