Vazquez won't be available to pitch Friday against the Cubs, Jason Mackey of the Pittsburgh Post-Gazette reports.

Vazquez pitched the last two days and three of the last four days, so manager Clint Hurdle will look elsewhere should a save opportunity arise Friday. Keone Kela and Richard Rodriguez are also said to be unavailable, leaving the Pirates without most of their typical higher-leverage options out of the bullpen.

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