Guzman will enter the concussion protocol after taking a knee to the head in Monday's game against the Padres, Stefan Stevenson of the Fort Worth Star-Telegram reports.
Guzman suffered the concussion when Christian Villanueva accidentally kneed him the head during a pickoff attempt at third base in the sixth inning. He will likely be placed on the 7-day disabled list Tuesday, and Joey Gallo, who replaced Guzman on the bases, figures to start at first base in the short term.