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Caleb Williams QB | CHI
Bears' Caleb Williams: Expected to start Sunday
Williams (hamstring) is expected to start Sunday's game against the Falcons, Adam Schefter of ESPN reports.
Williams is still listed as questionable for Sunday's game, and his status may not be officially announced until the Bears release their list of inactive players about 90 minutes before the 1:00 p.m. ET kickoff. However, it looks like the third-year quarterback will be back on the field after missing the Bears' last three games due to a torn right hamstring that he suffered in Week 2 against the Vikings. Given Williams' return, Tyson Bagent will likely serve as the Bears' backup while Case Keenum moves down to the QB3 role.
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Jalen Hurts QB | PHI
Eagles' Jalen Hurts: Placed on IR, out indefinitely
The Eagles placed Hurts (calf) on injured reserve Saturday, Adam Schefter of ESPN reports.
After prior reports indicated that a stint on injured reserve wasn't necessary, Hurts will now go on IR after multiple consultations with doctors. He'll be required to miss at least four games, and while Week 11 against the Steelers on Sunday, Nov. 22 is the earliest he can return, Schefter notes that Hurts' move to IR has the veteran quarterback sidelined "indefinitely." Tanner McKee will be the Eagles' starting QB for as long as Hurts is out of action, and rookie fifth-rounder Cole Payton will step into the Eagles' backup role.
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Marcus Mariota QB | WAS
Commanders' Marcus Mariota: Not available for Week 6
Mariota (knee) has been ruled out for Monday's game against the 49ers, Tashan Reed of The Washington Post reports.
As expected, Mariota will miss a second consecutive game due to a sprained MCL in his right knee, which he picked up during the Commanders' Week 4 loss to the Colts in London. Rookie seventh-rounder Athan Kaliakmanis will once again serve as Washington's backup quarterback behind Jayden Daniels for Monday night's game. The Commanders are on a bye for Week 7, so Mariota could be back in action for Week 8 against the Eagles on Sunday, Nov. 1.
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Jalen Hurts QB | PHI
Eagles' Jalen Hurts: IR stint not expected
Hurts remains sidelined indefinitely due to a superficial blood clot in his calf, but the Eagles are not planning to place the Philadelphia quarterback on injured reserve, Adam Schefter of ESPN reports.
Hurts was initially diagnosed with a blood clot in his leg prior to the Eagles' Week 5 loss to the Jaguars in London, and a follow-up ultrasound during Week 6 prep showed movement of the blood clot. He's already been ruled out for Sunday's game against the Panthers, and while there's no clear timeline for a return, it looks like an IR stint isn't in the cards for the seventh-year quarterback. Tanner McKee will start under center for Week 6 and for as long as Hurts is sidelined, while rookie fifth-rounder Cole Payton likely serves as the backup.
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Jalon Daniels QB | TB
Buccaneers' Jalon Daniels: Starting against Pittsburgh
Daniels will be the Buccaneers' starting quarterback against the Steelers after Baker Mayfield (right thumb) was ruled out.
It will be Daniels' third consecutive start under center, as Mayfield continues to be sidelined by a dislocated right thumb that prevented the veteran from practicing all week. Daniels led the Buccaneers to their first victory of the season in Week 5 against the Cowboys, when he completed 19 of 25 passes for 189 yards and a touchdown while turning seven carries into 23 yards.
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Case Keenum QB | CHI
Bears' Case Keenum: Unclear role for Week 6
Caleb Williams (hamstring) is listed as questionable for Sunday's game against Atlanta, but if he's not given the green light to return, then it's unclear whether Keenum or Tyson Bagent starts under center for Chicago, Larry Mayer of the Bears' official site reports.
It seems Keenum and Bagent would each have a 50-50 shot at starting Sunday if Williams isn't cleared to play, with head coach Ben Johnson saying Friday "we have two guys that are equally qualified" in reference to Keenum and Bagent. Keenum was the backup for each of the Bears' last two games, though he did take over in the fourth quarter of Chicago's Week 5 loss to Green Bay after Bagent threw his second pick of the game in the third period. Keenum was the starter and led the Bears to a Week 3 victory over the Eagles, when he completed 24 of 34 passes for 247 yards and two touchdowns while adding six yards and a score on four carries.
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Tyson Bagent QB | CHI
Bears' Tyson Bagent: Could be QB2 against Atlanta
Whether Bagent starts or serves in a backup role against the Falcons on Sunday depends largely on whether Caleb William (hamstring) is cleared to return from a three-game absence, Larry Mayer of the Bears' official site reports.
Williams strung together a trio of full practices during Week 6 prep, but he's not quite out of the woods yet as the team manages the third-year pro's hamstring injury. If Williams is not cleared to return, then it's not entirely clear whether Bagent or Keenum would get the starting nod, with head coach Ben Johnson being mum on those two options following Friday's practice. Bagent led the Bears to a Week 4 win against the Jets but was benched in the third quarter of Chicago's Week 5 loss to Green Bay after throwing a second interception.
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Tua Tagovailoa QB | ATL
Falcons' Tua Tagovailoa: Slated for QB2 duties in Week 6
With Michael Penix (ribs) cleared to play Sunday against the Bears, Tagovailoa will handle backup duties for the Falcons.
Tagoavailo replaced an injured Penix late last Sunday night against Baltimore and tossed the game-sealing interception in overtime to give the Ravens the win. The Falcons need Penix to maintain health this season, but he's shown little ability to do so early in his career, so there's a good chance Tagovailoa sees snaps again at some point in 2026.
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Tyler Huntley QB | BAL
Ravens' Tyler Huntley: Starting vs. Cleveland
Huntley will be the Ravens' starting QB against the Browns on Sunday after Lamar Jackson (ankle) was ruled out, Ryan Mink of the Ravens' official site reports.
Jackson will miss a second consecutive game due to an ankle injury that he sustained during the first half of the Ravens' Week 4 win against the Titans. As such, Huntley will once again be under center for Baltimore, and the veteran quarterback led his team to a Week 5 overtime victory against Atlanta, when he completed 24 of 32 passes for 201 yards and two touchdowns while turning six carries into 20 yards and a score. The Browns' 16 sacks are tied for seventh-most in the NFL, but the defense has also given up 10 touchdown passes across five games, which is tied for seventh-worst in the league.
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Caleb Williams QB | CHI
Bears' Caleb Williams: Questionable for Week 6
Williams (hamstring) is listed as questionable for Sunday's game against Atlanta.
Despite logging a trio of full practices during Week 6 prep, Williams' status remains up in the air ahead of the weekend. He's seeking his first game action since suffering a tear of his right hamstring in a Week 2 loss to the Vikings, which so far has forced him to miss the last three contests. It's unclear if head coach Ben Johnson will take a decision on his starting quarterback for Sunday down to the wire, but during Williams' absence, Case Keenum directed the offense in Week 3, while Tyson Bagent got the start in both of the last two outings.