The Detroit Pistons will take on the Boston Celtics at 7:30 p.m. ET on Friday at TD Garden. Boston is 18-7 overall and 10-1 at home, while Detroit is 11-17 overall and 4-9 on the road. Detroit is 2-4 against the spread in their last six games against Boston. The Celtics, meanwhile, are 5-2 against the spread in their last seven games overall. Boston is favored by nine-points in the latest Celtics vs. Pistons odds, while the Over-Under is set at 213.5. Before entering any Pistons vs. Celtics picks, you'll want to see the NBA predictions from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times, and last season it returned a whopping $4,280 on its top-rated NBA spread and money line picks. It's already returned almost $800 in profit on all its top-rated NBA picks during the 2019-20 season and entered Week 8 on a blistering 16-7 run on all top-rated NBA spread picks. Anybody who has followed it has seen huge returns.

Now, it has simulated Celtics vs. Pistons 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You can only see the pick at SportsLine.

Boston beat Dallas 109-103 on Wednesday behind 32 points and five rebounds from Kemba Walker. Jaylen Brown scored 26 points and Jayson Tatum added 24 points and eight rebounds. Walker has been sensational in his first season in Boston, averaging 23.5 points, 5.2 assists and 4.2 rebounds per game. He's scored 22 or more points in five of his last six outings, and now he'll look to take advantage of a Detroit defense that has given up 122 or more points in two of its last four games. 

Detroit, meanwhile, lost to Toronto 112-99 on Wednesday. A silver lining for the Pistons was the play of Andre Drummond, who dropped a double-double with 22 points and 18 rebounds. Drummond has an impressive 22 double-doubles in 26 games this season, and is scoring 17.8 points to go with his NBA-best 16.7 rebounds per game. 

So who wins Pistons vs. Celtics? And which side of the spread cashes in well over 50 percent of simulations? Visit SportsLine now to find out which side of the Celtics vs. Pistons spread you need to jump on Friday, all from the model that has crushed its NBA picks, and find out.