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The Los Angeles Rams host the Atlanta Falcons on Sunday in a matchup between teams looking to rebound from disappointing Week 1 losses. Despite big-time performances from Cooper Kupp and Aaron Donald, the Rams were blown out 31-10 by the Buffalo Bills. Los Angeles has had 10 days to rest and prepare for this Week 2 matchup. The Falcons led the New Orleans Saints for three quarters, but gave up 17 unanswered points in the fourth quarter to lose 27-26. Both teams have relatively clean injury reports with Leonard Floyd (knee) listed as questionable and Brian Allen (knee) out for Los Angeles. The Rams lead the all-time series 48-30-2.

Kickoff is at 4:05 p.m. ET on Sunday at SoFi Stadium in Los Angeles. Los Angeles is favored by 10 points in the latest Rams vs. Falcons odds from Caesars Sportsbook, and the over/under is set at 46.5. Before making any Falcons vs. Rams picks, you need to see the NFL predictions and betting advice from the proven simulation model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up more than $7,500 for $100 players on top-rated NFL picks since its inception. The model enters Week 2 of the 2022 NFL season on an incredible 139-98 run on top-rated NFL picks that dates back to the 2017 season. The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Rams vs. Falcons and just locked in its NFL Week 2 picks and predictions. You can head to SportsLine to see its picks. Here are several NFL betting lines for Falcons vs. Rams:

  • Rams vs. Falcons spread: Rams -10
  • Rams vs. Falcons over/under: 46.5 points
  • Rams vs. Falcons picks: See picks here

What you need to know about the Rams

The Rams looked rusty and underprepared in their season opening loss to the Bills. That should not be the case this week with head coach Sean McVay having 10 days to prepare for the Falcons. Matthew Stafford had his worst home start of his brief Los Angeles career, and will be looking to rebound against an Atlanta defense that gave up 269 passing yards and 2 touchdowns to Jameis Winston. 

Los Angeles will also be looking for a bounce-back game on the defensive side of the ball. Aside from Donald, the defense didn't play up to its potential against Buffalo. The Falcons' offense isn't as dynamic as the Josh Allen-led Buffalo group, which should give Los Angeles some confidence. Perennial All-Pro candidates Bobby Wagner and Jalen Ramsey remain among the best players in the NFL at their respective positions.

What you need to know about the Falcons

Meanwhile, Atlanta was hampered by 114 penalty yards against the New Orleans Saints this past Sunday. The Falcons lost 27-26 to New Orleans. Atlanta was up 23-10 at the end of the third quarter but couldn't hold on to the lead. RB Cordarrelle Patterson put forth a good effort for the losing side as he rushed for one TD and 120 yards on 22 carries.

The Falcons are in the midst of a rebuilding project, but they do have a few nice pieces on both sides of the ball. Second-year tight end Kyle Pitts is an emerging star with game-breaking ability. Veteran defensive tackle Grady Jarrett, who racked up 1.5 sacks in Week 1, remains one of the NFL's best interior defenders. Rookie wide receiver Drake London drew rave reviews in training camp, but will face a stiff test this week against Ramsey.

How to make Rams vs. Falcons picks

The model has simulated Rams vs. Falcons 10,000 times and the results are in. It is leaning Over on the point total, and it's also generated a point-spread pick that is hitting in more than 50% of simulations. You can only see the model's pick at SportsLine.

So who wins Falcons vs. Rams? And which side of the spread hits more than 50% of the time? Visit SportsLine now to see which side of the Rams vs. Falcons spread to jump on, all from the advanced model that is up nearly $7,500 on its NFL picks since 2017, and find out.