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It's a potential NFC playoff preview when the Philadelphia Eagles (1-1) travel to take on the New Orleans Saints (2-0) in one of the marquee games on the Week 3 NFL schedule. The Saints have been the hottest team in the league opening the season, beating Carolina and Dallas by a combined total of 91-29 and easily covering in both games. Philadelphia is coming off a heartbreaking loss to Atlanta on Monday, but did win its opener over the Packers in Brazil. Eagles receiver A.J. Brown (hamstring) has been ruled out.

Kickoff at Caesars Superdome is at 1 p.m. ET on Sunday. The latest Eagles vs. Saints odds via SportsLine consensus list New Orleans as the 2.5-point favorite. The over/under is 49 after opening at 45.5. Before entering any Saints vs. Eagles picks, you'll want to see the NFL predictions from the model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 3 of the 2024 NFL season on an incredible 187-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 41-22 roll on top-rated NFL picks since Week 7 of 2022. 

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

The model has set its sights on Philadelphia vs. New Orleans. You can head to SportsLine now to see its picks. Here are several NFL betting lines for the spreadmoney line and over/under:

  • Saints vs. Eagles spread: Saints -2.5
  • Saints vs. Eagles over/under: 49 points
  • Saints vs. Eagles money line: Saints -142, Eagles: +120
  • Saints vs. Eagles picks: See picks here

What you need to know about the Eagles

Brown's injury limits this offense a bit, but there are still several playmakers who can help the Eagles stay within the number. He had a costly drop late against the Falcons, but running back Saquon Barkley has a strong 46-204-2 rushing line on the year. DeVonta Smith is the leading receiver having recorded 14 catches for 160 yards and a touchdown. 

Quarterback Jalen Hurts will look to cut down on the interceptions after throwing three thus far. However, he remains one of the most dynamic QBs in the league. He has 461 passing yards and three scores through the air to go along with 118 yards and a rushing touchdown thus far in 2024. See picks at SportsLine

What you need to know about the Saints

Meanwhile, a well-balanced attack led the Saints over the Cowboys in every quarter on their way to victory on Sunday. Everything went the Saints' way against the Cowboys as the Saints picked up a 44-19 win. The matchup was pretty much decided by the half, when the score had already reached 35-16.

Alvin Kamara was a force for the Saints as he rushed for 115 yards and three touchdowns, and also picked up 65 receiving yards. Kamara made the highlight reel thanks to a 57-yard receiving touchdown in the second quarter. Derek Carr was another key player, throwing for 243 yards and two touchdowns on only 16 attempts. See picks at SportsLine.

How to make Saints vs. Eagles picks

The model has simulated Saints vs. Eagles 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread hits more than 50% of the time. You can only see the pick at SportsLine.

Who wins Eagles vs. Saints, and which side of the spread hits over 50% of the time? Visit SportsLine now to find out, all from the model that's on a 41-22 roll on top-rated NFL picks