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Bayern Munich look to move closer to their fifth consecutive quarterfinal appearance when they visit Lazio on Wednesday in the first leg of their Round of 16 tie in the UEFA Champions League. Bayern Munich haven't lost in the Round of 16 since 2018-19, when they were eliminated by eventual champion Liverpool. The only previous time Lazio reached this round was in 2020-21, when they suffered 4-1 and 2-1 losses to Bayern. 

Kickoff at Stadio Olimpico is set for 3 p.m. ET on Paramount+. Bayern are -145 favorites (risk $145 to win $100) in the latest Bayern Munich vs. Lazio odds, while Lazio are +425 underdogs. A 90-minute draw is priced at +290 and the over/under for total goals scored is 2.5. Before locking in any Lazio vs. Bayern Munich picks, you need to see what proven SportsLine soccer expert Brandt Sutton has to say.

Sutton, a former collegiate soccer player, has been SportsLine's top soccer editor for more than five years. He has followed soccer closely for much longer and factors in managerial tactics, projected lineups, and past performances to make the most informed decisions possible, keeping his finger on the pulse of the game all over the globe.

Sutton finished 2022 as SportsLine's top soccer expert with a 165-130-2 mark, returning nearly $2,200 for $100 players. He also excelled in Serie A with a 63-39-1 record, returning nearly $1,600. Anyone following him is way up.

Now, Sutton has broken down Bayern Munich vs. Lazio from every angle and just revealed his picks and UCL predictions. You can head to SportsLine now to see Sutton's picks. Here are the betting lines and trends for Lazio vs. Bayern Munich:

  • Bayern Munich vs. Lazio money line: Bayern -145, Lazio +425, Draw +290
  • Bayern Munich vs. Lazio over/under: 2.5 goals
  • Bayern Munich vs. Lazio spread: Bayern -0.5 (-145)
  • BM: Bayern have advanced past the Round of 16 in 11 of their last 12 opportunities
  • LAZ: The Biancocelesti lost both legs of their 2021 tie against Bayern by a combined 6-2 score
  • Bayern Munich vs. Lazio picks: See picks at SportsLine
  • Bayern Munich vs. Lazio streaming: Paramount+

Why you should back Bayern Munich

Bayern will be eager to bounce back from Saturday's 3-0 loss to Bayer Leverkusen in the German Bundesliga. The club earned 15 of a possible 18 points during the group stage of the Champions League, recording five victories while settling for a 0-0 draw against Copenhagen. Harry Kane has been an offensive force for Bayern Munich, as he has factored in on seven of the team's 12 goals to match three other players for most in the competition.

Kane is tied for fifth in the UCL with four goals, three of which he recorded in back-to-back wins against Galatasaray. The 30-year-old striker also has notched three assists, tying him for third in the competition. Lazio also will need to pay attention to midfielder Jamal Musiala, winger Leroy Sane, and forward Eric Maxim Choupo-Moting, who all converted when the teams met in the Round of 16 three years ago. See which team to pick here.

Why you should back Lazio

Captain Ciro Immobile was the top scorer in the group stage for the Biancocelesti with three goals. The 33-year-old striker netted the lone goal in a 1-0 victory against Feyenoord and recorded a brace in a 2-0 triumph over Celtic. Immobile also leads Lazio with six goals during Serie A play, including one in Saturday's 3-1 win versus Cagliari.

Three other players combined to produce the Biancocelesti's four other goals during group play. Spanish winger Pedro registered half of them, converting in a 2-1 win against Celtic and netting their lone tally in a 3-1 loss to Feyenoord. The 36-year-old has scored just once in 21 matches for Lazio this season in Serie A. See which team to pick here.

How to make Bayern Munich vs. Lazio picks

Sutton has broken down Wednesday's Champions League match from every possible angle and has locked in a confident best bet, while offering a full breakdown of this UCL match. He's sharing his Champions League picks and analysis only at SportsLine.

So who wins Bayern Munich vs. Lazio on Wednesday, and where does all the betting value lie? Visit SportsLine now to see which wagers in Lazio vs. Bayern Munich have all the value, all from the soccer expert who has been cashing in big on his soccer picks, and find out.