MLB: Milwaukee Brewers at San Francisco Giants
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The Los Angeles Dodgers and San Francisco Giants renew their rivalry when they open a four-game series on Monday at Oracle Park. The Dodgers (68-33) own the best winning percentage in baseball, while the Giants (51-51) are four games out of a wild card berth in the National League. Monday's game is the 10th meeting between the teams this season with Los Angeles holding a 6-3 edge in the season series. Los Angeles is a -140 favorite in the latest Dodgers vs. Giants odds from Caesars Sportsbook while San Francisco is a +118 underdog.

First pitch is set for 9:45 p.m. ET from San Francisco. The game is one of 10 on the MLB schedule for Monday. Elsewhere in the majors, the Mets' Max Scherzer makes his second start at Nationals Park since Washington traded him last year, and the Yankees and Mariners open a three-game series in New York. Before making any MLB picks or parlays, be sure to check out the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it enters Week 18 on a 20-14 roll on top-rated MLB picks, returning almost $400 for $100 players. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen profitable returns.

Now, the model has locked in four confident MLB best bets for Monday. They all involve games at 7:05 p.m. ET or later, so there's still time to get these MLB picks in. If you successfully parlay the picks, you'd be looking at a payout of more than 16-1. You can see the model's MLB picks only at SportsLine

Top MLB picks today

The model, which ran 10,000 simulations on each of Monday's games, likes the Chicago White Sox (-155) to beat Kansas City. The White Sox (51-50) have won back-to-back games and five of their last seven. Unlike the Royals (40-62), Chicago is still in the chase for a postseason spot, just two games behind the division-leading Twins in the AL Central and just 2.5 games out of a wild card berth.

The White Sox enter Monday's game with the edge in starting pitching. Chicago starter Michael Kopech has been on a roll recently, having allowed just four earned runs in his last three starts combined (2.30 ERA). The White Sox won all three games with Kopech earning the win in two. Meanwhile, Kansas City starter Brad Keller (5-11, 4.18) has given up eight runs on 10 hits and eight walks (6.30 ERA) in his last two starts, both Royals losses.

Featured Game | Chicago White Sox vs. Kansas City Royals

How to make MLB picks and parlays for Monday

The model also locked in three other best bets for Monday, including a play on a big National League underdog. You can see the model's MLB Monday best bets and parlay only at SportsLine.

What MLB picks should you target for a payout of more than 16-1? And what underdog does the model like on Monday? Visit SportsLine now to see the MLB best bets from an advanced model that is on a 20-14 roll on top-rated MLB money-line picks.