Coach Deion Sanders and the Colorado Buffaloes aim for a conference road win on Friday evening. Colorado visits Gesa Field to take on the Washington State Cougars in Pullman. Both teams are scuffling in recent weeks, with Washington State losing six straight games and Colorado losing six of the last seven. Both squads are 4-6 overall and 1-6 against Pac-12 competition this season. The loser will be eliminated from bowl contention. 

Kickoff is set for 10:30 p.m. ET. SportsLine consensus lists the Cougars as 4-point favorites, while the total number of points Vegas thinks will be scored, or the over/under, is 60.5 in the latest Colorado vs. Washington State odds, down three points from the opening line. Before making any Washington State vs. Colorado picks, you'll want to see the college football predictions from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a strong profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

The model has set its sights on Colorado vs. Washington State. You can head to SportsLine to see its picks. Here are several college football betting lines and trends for the Washington State vs. Colorado game:

  • Colorado vs. Washington State spread: Washington State -4
  • Colorado vs. Washington State over/under: 60.5 points
  • Colorado vs. Washington State money line: Washington State -187, Colorado +156
  • CU: The Buffaloes are 6-3-1 against the spread in the last 10 games
  • WSU: The Cougars are 4-6 against the spread in the last 10 games
  • Colorado vs. Washington State picks: See picks at SportsLine
  • Colorado vs. Washington State live stream: fubo (try for free)

Why Colorado can cover

Colorado's passing game is electric, led by quarterback Shedeur Sanders and receiver Xavier Weaver. Sanders is one of the best quarterbacks in the country, leading FBS with 292 pass completions this season. He has 3,144 passing yards, averaging 7.5 yards per attempt, with 30 total touchdowns. That touchdown mark ranks in the top eight of the nation, and Sanders has only three interceptions. He has six games with at least three touchdowns and five games with at least 348 passing yards. 

Weaver is one of the most prolific pass catchers in the nation, producing 65 receptions this season. That ranks in the top three of the Pac-12, and Weaver has 867 receiving yards and four touchdowns. He is also peaking right now, averaging 90 receiving yards per game over the last four outings. Colorado is generating more than 30 points per game this season, and the Buffaloes are also facing a Washington State offense that has struggling in conference play. The Cougars have averaged fewer than 20 points per game against conference opponents, and Washington State has the Pac-12's least potent rushing attack. See which team to pick here.

Why Washington State can cover

Washington State has the home-field advantage in this game, and Colorado has notable weaknesses that can be exploited. The Buffaloes have allowed 464.2 total yards per game, worst among Pac-12 teams this season, and Colorado is giving up 33.9 points per game. Opponents have scored at least 24 points in nine of the ten games against Colorado this season, and the Buffaloes are near the Pac-12 basement in rushing yards allowed per game (172.2) and per carry (4.7). 

On offense, Colorado has plenty of explosiveness, but the Buffaloes have allowed the second-most sacks (49) in all of FBS this season. Colorado also struggles to run the ball, generating fewer than 75 rushing yards per game and only 2.7 yards per carry. Washington State has allowed only 11 passing touchdowns, a top-three mark in the Pac-12, and the Cougars are capable of big things on offense. Washington State is in the top three of the conference in passing yards, led by Cameron Ward, and the Cougars generated 39 points, 483 total yards, and 32 first downs against California last week. See which team to pick here. 

How to make Washington State vs. Colorado picks

The model has simulated Colorado vs. Washington State 10,000 times and the results are in. The model is leaning Under the total, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins Colorado vs. Washington State, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the Washington State vs. Colorado spread to jump on, all from the advanced computer model that's up well over $2,000 on its top-rated college football spread picks since its inception, and find out.