Wells Fargo Center showcases an Atlantic Division matchup between the New York Knicks and the Philadelphia 76ers on Friday. The 76ers are 23-10 overall and 13-4 at home, with the Knicks entering at 19-15 overall and on a two-game winning streak. This meeting is the first of four scheduled matchups in 2023-24. De'Anthony Melton (back) is out for the 76ers, with Robert Covington (knee) and Furkan Korkmaz (illness) listed as questionable. Mitchell Robinson (ankle) is out for the Knicks, with Malachi Flynn (ankle) listed as questionable.

For this game, SportsLine consensus lists the 76ers as 6-point favorites, and tip-off is scheduled for 7:30 p.m. ET. The total number of points Vegas thinks will be scored, or the over/under, is 233 in the latest Knicks vs. 76ers odds. Before making any 76ers vs. Knicks picks, you need to see the NBA predictions and betting advice from SportsLine's advanced computer model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past five-plus seasons. The model enters Week 11 of the 2023-24 NBA season on a sizzling 106-59 roll on all top-rated NBA picks dating back to last season, returning well over $4,000. Anyone following it has seen huge returns.

Now, the model has set its sights on Knicks vs. Sixers and just locked in its picks and NBA predictions. You can head to SportsLine now to see the model's picks. Now, here are several NBA odds and betting lines for Sixers vs. Knicks:

  • Knicks vs. 76ers spread: 76ers -6
  • Knicks vs. 76ers over/under: 233 points
  • Knicks vs. 76ers money line: 76ers -232, Knicks +188
  • NYK: The Knicks are 9-10-1 against the spread in road games
  • PHI: The 76ers are 13-4 against the spread in home games
  • Knicks vs. 76ers picks: See picks at SportsLine

Why the Knicks can cover

New York has two-way strengths that should present in this matchup. The Knicks are in the top 10 of the NBA in offense, scoring 1.17 points per possession. New York is led by high-end scorers in Julius Randle and Jalen Brunson, and Randle enters on a notable hot streak. He has scored 20 points or more in 19 straight games, and Randle is averaging 28.5 points and 9.2 rebounds per game this season. 

New York's offense also has elite numbers in free throw creation (24.5 attempts per game) and offensive rebounding, with the Knicks averaging 16.6 second-chance points per game and securing more than 33.4% of missed shots on the glass. The Knicks connect on 37.5% of 3-point attempts on offense and, on the other end, New York is elite in free throw prevention. Opponents average fewer than 21 free throw attempts per game and the Knicks, and New York also boasts top-eight metrics in defensive rebound rate (73.0%), second-chance points allowed (12.8 per game) and points allowed in the paint (47.1 per game) this season. See which team to pick here.

Why the 76ers can cover

Wells Fargo Center provides a strong home-court advantage, with Philadelphia posting a 13-4 home record this season. The 76ers have the second-best net rating (+13.5) in the NBA, thoroughly out-playing opponents in Philadelphia. The Sixers' offense is also excellent, including a top-four mark in overall efficiency (120.4 points per 100 possessions) and an elite free throw profile. The 76ers are in the top two of the league in free throw attempts (27.1 per game) and free throw accuracy (84.2%), and Philadelphia is in the top eight in turnover rate (12.7%) and offensive rebound rate (30.3%).

On defense, Philadelphia is tremendous, yielding only 1.10 points per possession and leading the league with 9.1 steals per game. The 76ers are in the top eight of the NBA in turnover creation (14.7 per game), 3-point defense (34.0%), and opponent field goal percentage (46.1%), with Joel Embiid providing top-tier rim protection on the back end. See which team to pick here.

How to make 76ers vs. Knicks picks

SportsLine's model is leaning Under on the total, projecting 230 combined points. The model also says one side of the spread hits in well over 50% of simulations. You can only see the model's picks at SportsLine.

So who wins Knicks vs. Sixers, and which side of the spread hits in well over 50% of simulations? Visit SportsLine now to see which side of the spread you need to jump on, all from the model on a 106-59 roll on top-rated NBA picks, and find out.