The Los Angeles Lakers will face off against the Memphis Grizzlies in a Western Conference matchup on Friday. Memphis is 27-53 overall and 9-30 at home, while Los Angeles is 45-35 overall and 17-21 on the road. The Lakers are 2-1 against the Grizzlies this season, most recently winning 136-124 at Memphis on March 27. 

Tipoff is set for 8 p.m. ET on Friday at FedExForum in Memphis. The Lakers are 15.5-point favorites in the latest Lakers vs. Grizzlies odds, according to the SportsLine consensus, and the over/under is set at 225.5 points. Before entering any Grizzlies vs. Lakers picks, you need to see the NBA predictions and betting advice from SportsLine's advanced computer model

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past five-plus seasons. The model enters Week 25 of the 2023-24 NBA season on a sizzling 83-58 roll on all top-rated NBA picks this season, returning more than $2,200. Anyone following it has seen huge returns.

The model has set its sights on Los Angeles vs. Memphis. You can head to SportsLine to see its picks. Here are several NBA odds and betting lines for Lakers vs. Grizzlies:

  • Grizzlies vs. Lakers spread: Lakers -15.5
  • Grizzlies vs. Lakers over/under: 225.5 points
  • Grizzlies vs. Lakers money line: Grizzlies: +738, Lakers: -1250
  • LAL: The Lakers are 6-4 ATS over their last 10 games
  • MEM: The Grizzlies are 6-1 ATS over their last seven games when underdogs by at least eight points
  • Grizzlies vs. Lakers picks: See picks here

What to know about the Lakers

The Lakers are 9-3 over their last 12 games despite entering Friday off back-to-back losses. The Lakers fell to the Warriors, 134-120, on Tuesday in their last contest. LeBron James had 33 points, seven rebounds and 11 assists against Golden State and he's questionable with an ankle injury for Friday. James has been on the injury report for the majority of the season, so it's not a new injury. Anthony Davis missed Tuesday with a headache but he's probable for Friday.

The Lakers will be playing in the 2024 Play-In Tournament, the only question is how many games and will they have to play in the first win-or-go-home contest. Los Angeles is tied with the Kings and Warriors for the No. 8-No. 10 seeds in the West. The Lakers are currently 10th due to the tiebreakers. See which team to pick here.

What to know about the Grizzlies

The Grizzlies enter on a three-game losing streak, most recently falling to the Cavaliers, 110-98, on Wednesday. Jake LaRavia had a huge performance with 32 points, including making 8 of 11 3-pointers, as the Grizzlies are giving younger players the chance for increased playing time to close out the season. It's been an extremely difficult season for Memphis battling injuries and suspensions all season long, but for the younger players, this is their chance to prove they have the potential for extended NBA careers.

GG Jackson scored 22 points and Scotty Pippen Jr. added 18 points against Cleveland. LaRavia is averaging 16.3 points on 31.5 minutes over four games in April compared to averaging just 9.8 ppg this season. The Grizzlies have 13 players ruled out for Friday, but those on the floor are playing for their NBA futures, which means there should be no shortage of effort. See which team to pick here.

How to make Grizzlies vs. Lakers picks

The model has simulated Lakers vs. Grizzlies 10,000 times and the results are in. The model is leaning Under and it also says one side of the spread hits over 50% of the time. You can only see the pick at SportsLine.

So who wins Lakers vs. Grizzlies, and which side of the spread hits over 50% of the time? Visit SportsLine now to see which side of the Grizzlies vs. Lakers spread you need to jump on Friday, all from the model on an 83-58 roll on all top-rated NBA picks this season, and find out.