Any time the Ravens and Steelers square off, it's going to be one of the highlighted matchups of the week. The Week 5 NFL schedule will be no exception when the two meet in Pittsburgh. Baltimore is a four-point favorite in the latest Week 5 NFL odds according to the SportsLine consensus. The Steelers have won five of their last six games against the Ravens, but Lamar Jackson only started two of those six games. Which AFC North team should you play in Week 5 NFL office pool picks? Their last four matchups have been decided by three points or fewer, so this could be one of the toughest games for anyone making NFL confidence pool picks. Before you make your NFL predictions, you need to see the Week 5 NFL football pool picks from SportsLine's proven computer model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 5 of the 2023 NFL season on an incredible 168-118 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 22-10 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up. 

Now, the model has simulated the entire Week 5 NFL schedule 10,000 times and generated its optimal NFL pick'em plays. Head to SportsLine to see them now.

Top Week 5 NFL office pool predictions

One of the top Week 5 NFL predictions from the model: The Detroit Lions (-9.5) comfortably beat the Carolina Panthers at home. The Lions are coming off back-to-back 14-point victories, knocking off the Falcons, 20-6, in Week 3 before a dominant 34-20 victory at Lambeau Field against the Packers to improve to 3-1. Detroit has additional rest this week after its Thursday Night Football victory over Green Bay.

The Panthers are 0-4 overall this season and went 2-6 on the road last year. They have one of the worst rush defenses in the NFL and the Lions are a team looking to grind on the ground. Carolina is allowing 4.7 yards per rush, tied for the fourth-most in the NFL, while surrendering 136.2 rushing yards per game. The Lions have the fourth-most rushing attempts and are averaging four yards per carry. SportsLine's model projects David Montgomery and Jahmyr Gibbs to combine for more than 100 rushing yards, helping the Lions win outright in well over 70% of simulations. See the rest of the model's Week 5 NFL pool picks here.

How to make Week 5 NFL office pool picks

The model also made the call on every other Week 5 NFL game and has strong picks for potentially close NFL matchups like Cowboys vs. 49ers, Saints vs. Patriots, and Packers vs. Raiders. It's also calling for several favorites to struggle big-time. You can only see all of the model's NFL pool picks here.

So who should you pick in every Week 5 NFL game, and which favorites should you avoid? Visit SportsLine now to get optimal NFL office pool picks, all from a proven computer model that has returned over $7,000 since its inception, and find out.