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The quarterbacks came out firing in Week 1, at least some of them did. But Week 2 promises to flip a lot of those scripts. That's where we come in to help you see what's ahead.

It is be our objective to find you the quarterbacks you'll want to move in and out of your lineups based on matchups every week. Playing matchups is key to the position and we're here to find you the perfect path. Jamey Eisenberg's Start 'Em & Sit 'Em calls at running back and wide receiver can help you find the answers for Week 2. 

More Week 2 help: QB Preview | RB Preview | WR Preview | TE Preview | Waiver Wire

START 'EM & SIT 'EM
Quarterbacks
Start 'Em
Projections powered by Sportsline
PHI Philadelphia • #1
Age: 24 • Experience: 3 yrs.
Weekly Breakdown
MATCHUP
vs SF SF -3.5 O/U 50
OPP VS QB
27th
PROJ PTS
20.3
QB RNK
10th
YTD Stats
PAYDS
264
RUYDS
62
TD
3
INT
0
FPTS/G
34.7
Hurts was spectacular in Week 1 at Atlanta with 264 passing yards and three touchdowns, and he also added 62 rushing yards. He gets a tougher opponent in Week 2 against San Francisco, but the 49ers just lost cornerback Jason Verrett (ACL) and could be without linebacker Dre Greenlaw (groin). It's also the second consecutive road game for the 49ers, and Hurts should have the chance for another quality outing in his home debut in 2021.
LAR L.A. Rams • #9
Age: 34 • Experience: 14 yrs.
Weekly Breakdown
MATCHUP
@ IND LAR -4 O/U 47.5
OPP VS QB
28th
PROJ PTS
21.8
QB RNK
11th
YTD Stats
PAYDS
321
RUYDS
-5
TD
3
INT
0
FPTS/G
30.8
Stafford looked more than comfortable in his first game as the Rams quarterback in Week 1 against the Bears. He passed for 321 yards and three touchdowns, and he should stay hot against the Colts this week. Indianapolis could again be without cornerback Xavier Rhodes (calf), and the Colts couldn't stop Russell Wilson last week when he had 254 passing yards and four touchdowns.
CIN Cincinnati • #9
Age: 26 • Experience: 3 yrs.
Weekly Breakdown
MATCHUP
@ CHI CHI -2.5 O/U 45
OPP VS QB
23rd
PROJ PTS
20.5
QB RNK
15th
YTD Stats
PAYDS
261
RUYDS
2
TD
2
INT
0
FPTS/G
22.6
I was skeptical of starting Burrow in Week 1 against the Vikings in his first game back from last year's knee injury, but he looked solid in his return. Burrow passed for 261 yards and two touchdowns, and he needed just 27 attempts (20 completions), which was a career low, to score 22 Fantasy points. I'm confident he'll have similar success this week against the Bears, making him a low-end starting option in all leagues.
TEN Tennessee • #17
Age: 34 • Experience: 11 year
Weekly Breakdown
MATCHUP
@ SEA SEA -5.5 O/U 54
OPP VS QB
14th
PROJ PTS
18.8
QB RNK
13th
YTD Stats
PAYDS
212
RUYDS
17
TD
2
INT
1
FPTS/G
16.1
Tannehill was a disaster in Week 1 against the Cardinals, but he should rebound this week. Arizona sacked Tannehill six times, and he was limited to 212 passing yards, one touchdown and one interception, along with 17 rushing yards, one touchdown and two fumbles. Things should only improve at Seattle in what should be a high-scoring game based on the projected total score of 54 points, according to the Caesars Sportsbook. Carson Wentz scored 22 Fantasy points against the Seahawks last week.
NO New Orleans • #2
Age: 29 • Experience: 8 yrs.
Weekly Breakdown
MATCHUP
@ CAR NO -3.5 O/U 44.5
OPP VS QB
14th
PROJ PTS
19.7
QB RNK
14th
YTD Stats
PAYDS
148
RUYDS
37
TD
5
INT
0
FPTS/G
39.6
Winston likely won't have it as easy in Week 2 as he did in Week 1 against the Packers when he attempted only 20 passes (14 completions) but scored five touchdowns. He finished with 148 passing yards, and he also added 37 rushing yards. The Panthers beat up Jets rookie quarterback Zach Wilson last week with six sacks, but he still managed to score 20 Fantasy points. Winston could be on his way to a great first season as the new starter in New Orleans, and I expect another quality Fantasy outing this week.
Sleepers
Projections powered by Sportsline
MIA Miami • #5
Age: 30 • Experience: 9 yrs.
Weekly Breakdown
MATCHUP
@ JAC DEN -6 O/U 45.5
OPP VS QB
22nd
PROJ PTS
22.9
QB RNK
16th
YTD Stats
PAYDS
264
RUYDS
19
TD
2
INT
0
FPTS/G
24.4
The Broncos lost standout receiver Jerry Jeudy (ankle) last week at the Giants, but hopefully Tim Patrick and K.J. Hamler can help Courtland Sutton and Noah Fant fill the void. It might not matter this week against the Jaguars, who allowed 27 Fantasy points against Tyrod Taylor in Week 1. Bridgewater had 264 passing yards and two touchdowns, along with 19 rushing yards, in Week 1 and could replicate that kind of performance this week. Consider him a low-end starter in all leagues.
LAR L.A. Rams • #17
Age: 27 • Experience: 5 yrs.
Weekly Breakdown
MATCHUP
vs HOU CLE -12.5 O/U 48
OPP VS QB
20th
PROJ PTS
22.7
QB RNK
17th
YTD Stats
PAYDS
321
RUYDS
7
TD
0
INT
1
FPTS/G
12.6
Mayfield played well in Week 1 at Kansas City with 321 passing yards on 21-of-28 attempts, but he had no touchdowns and one interception. The Browns scored three rushing touchdowns, so Mayfield was left with just 11 Fantasy points. Even with Odell Beckham (knee) out for this game, Mayfield should have the chance to do well in a quality matchup. The Texans had three interceptions on Trevor Lawrence last week, but he also had 332 passing yards and three touchdowns. Mayfield is a decent starter in 14-team leagues or larger.
NYG N.Y. Giants • #2
Age: 33 • Experience: 12 yrs.
Weekly Breakdown
MATCHUP
@ CLE CLE -12.5 O/U 48
OPP VS QB
30th
PROJ PTS
18.2
QB RNK
NR
YTD Stats
PAYDS
291
RUYDS
40
TD
2
INT
0
FPTS/G
27.6
Taylor has a tougher matchup in Week 2 at the Browns than he did in Week 1 against the Jaguars, but he still might have decent production. He passed for 291 yards and two touchdowns against Jacksonville but also added four carries for 40 yards, and hopefully he'll continue to run like that all season. The Browns struggled with Patrick Mahomes in Week 1 (39 Fantasy points), which is no surprise, but Cleveland also allowed five quarterbacks to run for at least 34 yards last year.
Sit 'Em
Projections powered by Sportsline
JAC Jacksonville • #16
Age: 23 • Experience: 2 yrs.
Weekly Breakdown
MATCHUP
vs DEN DEN -6 O/U 45.5
OPP VS QB
18th
PROJ PTS
17.4
QB RNK
21st
YTD Stats
PAYDS
332
RUYDS
-2
TD
3
INT
3
FPTS/G
25.2
Cornerback Ronald Darby (hamstring) is out for the Broncos, but pass rusher Bradley Chubb (ankle) could return this week. Even if Chubb is out, it should be tough for Lawrence to have a big game against Denver. The Texans were able to get three interceptions against Lawrence last week, and the Broncos are a much tougher opponent, even at Jacksonville.
LV Las Vegas • #4
Age: 31 • Experience: 9 yrs.
Weekly Breakdown
MATCHUP
@ PIT PIT -5.5 O/U 47
OPP VS QB
11th
PROJ PTS
17
QB RNK
20th
YTD Stats
PAYDS
435
RUYDS
6
TD
2
INT
1
FPTS/G
28
Carr had a solid stat line in Week 1 against Baltimore with 435 passing yards, two touchdowns and one interception, but most of that came late in the game. Carr had 267 yards, two touchdowns and an interception in the fourth quarter and overtime, and that should be hard to replicate on the road at Pittsburgh. The Steelers just held Josh Allen to 18 Fantasy points at Buffalo in Week 1, and Carr should be in that range this week.
IND Indianapolis • #2
Age: 37 • Experience: 15 yrs.
Weekly Breakdown
MATCHUP
@ TB TB -12.5 O/U 52
OPP VS QB
25th
PROJ PTS
17
QB RNK
23rd
YTD Stats
PAYDS
164
RUYDS
8
TD
0
INT
0
FPTS/G
7.3
Ryan was a disaster in his first game under new coach Arthur Smith and without Julio Jones. He finished with just 164 passing yards on 21-of-35 completions, with no touchdowns or interceptions, and he was sacked three times against the Eagles. He could have more success throwing against the Buccaneers in Week 1 with cornerback Sean Murphy-Bunting (elbow) out, but it's hard to trust Ryan right now after his disappointing performance in Week 1.
MIA Miami • #1
Age: 24 • Experience: 3 yrs.
Weekly Breakdown
MATCHUP
vs BUF BUF -3.5 O/U 48.5
OPP VS QB
6th
PROJ PTS
17.9
QB RNK
19th
YTD Stats
PAYDS
202
RUYDS
1
TD
2
INT
1
FPTS/G
18.1
Tagovailoa gets Will Fuller back from suspension for this game, so this will be the first time Jaylen Waddle, DeVante Parker and Fuller are together in live action after Fuller and Parker were hurt in the preseason. That's a positive for Tagovailoa. The negative is this is a tough Bills defense that just limited Ben Roethlisberger to 188 passing yards and one touchdown. Tagovalia had 18 Fantasy points in Week 1 at New England, and I expect him to be in that range again this week.
Bust Alert
Projections powered by Sportsline
MIN Minnesota • #8
Age: 34 • Experience: 11 year
Weekly Breakdown
MATCHUP
@ ARI ARI -4.5 O/U 51
OPP VS QB
8th
PROJ PTS
18.3
QB RNK
18th
YTD Stats
PAYDS
351
RUYDS
0
TD
2
INT
0
FPTS/G
26
The Vikings offensive line struggled against the Bengals in Week 1, and now they have to block Chandler Jones and J.J. Watt, with Jones getting five sacks last week against Tannehill. Now, Cousins still managed to pass for 351 yards and two touchdowns in overtime at Cincinnati, and he's always a potential starter when Justin Jefferson and Adam Thielen are healthy. But Arizona also got three turnovers against Tannehill in Week 1. For this week, consider Cousins a low-end starter in deeper one-quarterback leagues only.

So who should you start and sit this week? And which surprising quarterback could lead you to victory? Visit SportsLine now to get Week 2 rankings for every position, plus see which QB is going to come out of nowhere to crack the top 10, all from the model that has out-performed experts big-time.