Both teams face a short week coming off rough outings when the Pittsburgh Panthers host the Boston College Eagles on Thursday night at Acrisure Stadium. Boston College (6-4, 3-3) enters the Atlantic Coast Conference matchup off its first loss in the past six games, while Pittsburgh (2-8, 1-5) has lost four in a row. The Panthers lost their eighth game in their past nine last Saturday, a 28-13 home setback to Syracuse. The Eagles were run over by Virginia Tech in a 48-22 loss on their home turf last weekend. Pittsburgh has a 17-15 lead in the all-time series, but Boston College has won the past two, the latest a 31-20 home victory in 2020.

Thursday's kickoff in Pittsburgh is set for 7 p.m. ET. The Panthers are 2.5-point favorites in the latest Boston College vs. Pittsburgh odds via SportsLine consensus, and the over/under for total points scored is 46.5. Before you make any Pittsburgh vs. Boston College picks, be sure to check out the college football predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Boston College vs. Pitt and just revealed its picks and predictions. You can visit SportsLine to see the model's CFB picks. Here are several college football odds and trends for Pitt vs. Boston College: 

  • Boston College vs. Pittsburgh spread: Panthers -2.5
  • Boston College vs. Pittsburgh over/under: 46.5 points
  • Boston College vs. Pittsburgh money line: Eagles +116, Panthers -139
  • BC: Is 14-14 ATS as an underdog under Jeff Hafley (since 2020).
  • PIT: Is 25-19 ATS following a loss under Pat Narduzzi (since 2015).
  • Boston College vs. Pittsburgh picks: See picks at SportsLine
  • Boston College vs. Pittsburgh live stream: fubo (try for free)

Why Pittsburgh can cover

The Panthers are 5-6 against the spread after a loss since the start of last season. Given their issues at quarterback, they will rely on the run game and defense. Boston College has allowed 572 rushing yards over the past two games, so Pitt running backs Rodney Hammond and C'Bo Flemister should be able to get going. They have combined for 714 rushing yards and five TDs, with both averaging at least 4.0 yards per carry. The Eagles are yielding 5.2 per rush, ranking 120th in FBS.      

The Panthers are 3-2 against the spread at home and pulled off a 38-21 victory against Louisville last month. The Cardinals were ranked 14th at the time, and Pitt had three takeaways, while quarterback Christian Veilleux threw for 200 yards and two TDs in his first start. The Eagles allow the third-most points in the ACC (28.5 per game). Pitt allows 212 passing yards per game and BC averages less than 200, so the Panthers defense will sell out against the run. See which team to pick here.

Why Boston College can cover

The Eagles have covered the spread in three of the past five games, and all three were outright victories as underdogs. Quarterback Thomas Castellanos gives BC a chance to compete with anyone when he is on his game. The sophomore is third in the ACC in rushing with 806 yards and seventh in passing with 1,824 yards, recording 13 TD passes and 10 on the ground. Lewis Bond has caught five of those TD passes and has 500 receiving yards, averaging 13.2 per catch. The Eagles average 26.4 points per game, while the Panthers score 19.9, the fewest in the ACC.

Boston College leads the ACC in rushing at 202 yards per game. Syracuse rushed for 382 last week and attempted just eight passes against Pitt. The Eagles' strength on defense is against the pass, and with Pitt having QB issues, they will be able to focus on stopping the run. Pitt has the ACC's worst rushing offense, averaging just 98 yards per game (117th in FBS). See which team to pick here.

How to make Boston College vs. Pittsburgh picks

SportsLine's model is leaning Over on the point total, projecting the teams to combine for 52 points. The model also says one side of the spread is hitting well over 50% of the time. You can only see the model's pick at SportsLine

So who wins Pittsburgh vs. Boston College, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has notched a profit of well over $2,000 on its top-rated college football spread picks, and find out.