The Colorado State Rams (3-5) and the Wyoming Cowboys (5-3) link up in a Mountain West conference tilt known as the Border War on Friday night. This matchup features an exciting offense and a strong defense. Colorado State ranks fourth in the Mountain West in total offense (406.5). On the flip side, Wyoming sits fourth in the conference in total defense (388.3). CSU wide receiver Tory Horton (leg) will be a game-time decision. 

Kickoff from War Memorial Stadium in Wyoming is set for 8 p.m. ET on CBS Sports Network. The Cowboys are 6-point favorites in the latest Colorado State vs. Wyoming odds from the SportsLine consensus, while the over/under for total points scored is 42.5. Before making any Wyoming vs. Colorado State picks, be sure to check out the college football predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Colorado State vs. Wyoming and just revealed its picks and predictions. You can visit SportsLine now to see the model's picks. Now, here are several college football odds and trends for Wyoming vs. Colorado State:

  • Colorado State vs. Wyoming spread: Cowboys -6
  • Colorado State vs. Wyoming over/under: 42.5 points  
  • Colorado State vs. Wyoming money line: Cowboys -237, Rams +193
  • CSU: Colorado State is 1-6 in its last seven games on the road
  • WYO: Wyoming is 5-0 in its last five games at home
  • Colorado State vs. Wyoming picks: See picks at SportsLine 
  • Colorado State vs. Wyoming live stream: fubo (try for free)

Why Wyoming can cover

Senior quarterback Andrew Peasley is an accurate passer for the Cowboys. Peasley has been taking care of the ball, only tossing three interceptions thus far in 2023. The Oregon native is completing 58% of his throws for 1,055 passing yards and 13 touchdowns. He's thrown for at least two touchdowns in four games in 2023.

On Oct. 14 against No. 25 Air Force, he went 15 of 25 for a season-high 212 passing yards and three touchdowns. Junior running back Harrison Waylee returned to the lineup last week and provided a massive boost to the ground game. Waylee has 85 rushes for 588 yards and three touchdowns in five games. On Sept. 30, he finished with 191 yards and one score. See which team to pick here.

Why Colorado State can cover

Senior defensive lineman Mohamed Kamara is the biggest difference-maker up front for the Rams. Kamara uses his excellent power and quickness to create a push in the backfield. The New Jersey native is leading the conference in total sacks (10.5) with 38 total tackles and two forced fumbles. In Week 8 versus UNLV, he racked up seven tackles and one sack.

Junior safety Jack Howell is a very well-rounded player. The Colorado native is second in the Mountain West in total tackles (78) with one forced fumble and one interception. He's logged double-digit stops in three games thus far. In Week 7 against Boise State, Howell registered a season-high 15 tackles. See which team to pick here.

How to make Colorado State vs. Wyoming picks

SportsLine's model is leaning Over on the total, projecting the teams to combine for 46 points. The model also says one side of the spread hits in well over 50% of simulations. You can only see the model's pick at SportsLine.

So who wins Colorado State vs. Wyoming, and which side of the spread hits in well over 50% of simulations? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has notched a profit of well over $2,000 on its top-rated college football spread picks, and find out.