The South Florida Bulls battle the UTSA Roadrunners in a key American Athletic Conference matchup on Friday night in San Antonio. The Bulls (5-5, 3-3 AAC), who have won two of the past three games, are coming off a 27-23 victory over Temple on Saturday. The Roadrunners (7-3, 6-0 AAC), who have won six in a row and 16 consecutive conference games, defeated Rice 34-14 on Saturday. This will be the first meeting between the schools.

The game will kick off at 9 p.m. ET from the Alamodome. USF is averaging 264.6 passing yards per game in 2023, while UTSA averages 238. The Roadrunners are favored by 15.5 points in the latest South Florida vs. UTSA odds via SportsLine consensus, while the over/under for total points scored is 66.5. Before making any UTSA vs. South Florida picks, be sure to check out the college football predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on South Florida vs. UTSA and just revealed its picks and predictions. You can visit SportsLine to see the model's CFB picks. Here are several college football odds and trends for UTSA vs. USF: 

  • South Florida vs. UTSA spread: UTSA -15.5
  • South Florida vs. UTSA over-under: 66.5 points
  • South Florida vs. UTSA: South Florida +527, UTSA -773
  • USF: The Bulls are 2-18 in their last 20 games on the road
  • UTSA: The Roadrunners are 4-1-1 ATS in their last six games
  • South Florida vs. UTSA picks: See picks at SportsLine
  • South Florida vs. UTSA live stream: fubo (try for free)

Why UTSA can cover

Among the Roadrunners' top receivers is senior Tykee Ogle-Kellogg. The sixth-year veteran has 28 receptions for 481 yards (17.2 average) and six touchdowns this season. In a 41-27 win over East Carolina on Oct. 28, Ogle-Kellogg caught five passes for 85 yards (17.0 average) and two touchdowns. For his career, he has 84 catches for 1,264 yards (15.0 average) and 14 touchdowns, including a long of 70 yards.

Defensively, sophomore linebacker Trey Moore has been a force. Not only is he one of the team leaders in tackles with 42, including 27 solo, but he has a team-high 14 sacks for 89 yards. He also has one forced fumble, one fumble recovery, two pass breakups and one interception. He had two sacks against Rice on Saturday, and registered a season-high 3.5 sacks in a 41-20 win over UAB on Oct. 14. He also had one forced fumble and one fumble recovery in that game. See which team to pick here.

Why South Florida can cover

Freshman quarterback Byrum Brown is a big part of the Bulls' offense and is a dual threat. He not only leads the team in passing, throwing for 2,538 yards and 18 touchdowns, but he is second on the team in yards rushing at 659 with nine rushing scores. In last week's win over Temple, he threw for 316 yards and one touchdown, while rushing for another. A week earlier in a loss at Memphis, Brown completed 81.6% of his passes for 357 yards and five touchdowns.

Defensively, senior linebacker Jhalyn Shuler leads the way. He has a team-high 68 tackles, including 34 solo, with two sacks for 18 yards. He has also broken up four passes, while forcing one fumble. In the win over Temple, he made nine stops, including six solo, with one pass breakup. In a 17-3 loss to 10th-ranked Alabama on Sept. 16, he made 11 tackles, including two solo, with one pass breakup. See which team to pick here

How to make UTSA vs. South Florida picks

SportsLine's model is leaning Over on the point total, projecting the teams to combine for 73 points. The model also says one side of the spread is hitting well over 60% of the time. You can only see the model's pick at SportsLine.

So who wins South Florida vs. UTSA, and which side of the spread hits well over 60% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has notched a profit of well over $2,000 on its top-rated college football spread picks, and find out.