When it comes to setting your Fantasy football lineup at running back or tight end, deciding who to start is often an exercise in choosing the best of a bunch of bad options. The opposite is usually true at quarterback and especially in 2020, when there might be as many as two viable starting options available for each team. When it comes to setting the QB spot in your lineup, the concern isn't that you'll start someone bad, but that you'll bench someone better. 

It's a good problem to have, but it can still be a problem,  and you still want to make the right decision. That's what Jamey Eisenberg's Start 'Em & Sit 'Em calls are here for. Check out who Jamey says should be in your lineup below, and then head over to Heath Cummings' quarterback preview for matchup notes, key stats, projections, and more for Week 1. 

START 'EM & SIT 'EM
Quarterbacks
Start 'Em
Projections powered by Sportsline
IND Indianapolis • #2
Age: 39 • Experience: 16 yrs.
Weekly Breakdown
MATCHUP
vs SEA SEA -1.5 O/U 49
OPP VS QB
16th
PROJ PTS
21.2
QB RNK
6th
2019 Stats
PAYDS
4466
RUYDS
147
TD
27
INT
14
FPTS/G
21.2
This game has shootout potential, as William Hill has the expected point total at 49. Ryan at home is always a good play, especially against a defense like the Seahawks, who could have a questionable pass rush. Ryan has top-five upside this week, and hopefully we'll see plenty of production from his playmakers in the passing game with Julio Jones, Calvin Ridley and Hayden Hurst.
PIT Pittsburgh • #7
Age: 42 • Experience: 18 yrs.
Weekly Breakdown
MATCHUP
@ NYG PIT -5.5 O/U 47.5
OPP VS QB
28th
PROJ PTS
17.6
QB RNK
9th
2019 Stats
PAYDS
351
RUYDS
7
TD
0
INT
1
FPTS/G
6
Roethlisberger is reportedly back at 100% from last year's elbow injury, and he should be excited to light up this Giants secondary on Monday night. Roethlisberger was a candidate for Start of the Week in Week 1, and I'm expecting a solid performance on a national stage. The Giants were one of eight teams to allow 30 touchdown passes in 2019, and this secondary is rebuilding once again. It might not be a top-five performance for Roethlisberger this week, but a top-10 outing is possible.
CAR Carolina • #1
Age: 35 • Experience: 12 yrs.
Weekly Breakdown
MATCHUP
vs MIA NE -6.5 O/U 43
OPP VS QB
31st
PROJ PTS
20.4
QB RNK
15th
2019 Stats
PAYDS
572
RUYDS
-2
TD
0
INT
1
FPTS/G
8
Newton was another candidate for Start of the Week as well, and I'm hopeful he's back at 100 percent and ready to dominate. The Dolphins defense should be better from 2019, but Newton should still be successful with his arm and legs. It should be fun to watch offensive coordinator Josh McDaniels use Newton in their first game together, especially against former Patriots defensive coordinator Brian Flores.
KC Kansas City • #11
Age: 31 • Experience: 9 yrs.
Weekly Breakdown
MATCHUP
@ WAS PHI -6 O/U 42.5
OPP VS QB
25th
PROJ PTS
20
QB RNK
12th
2019 Stats
PAYDS
4039
RUYDS
243
TD
28
INT
7
FPTS/G
20.6
A repeat of last year's Week 1 performance against the Washington Football Team would be welcomed when Wentz had 313 passing yards and three touchdowns for 31 Fantasy points. I wouldn't go in expecting that, but I wouldn't be shocked if it happened either, especially against this secondary. It would be great if Wentz had his full complement of weapons, as well as a healthy offensive line, but he's still worth trusting in a big way in Week 1.
DET Detroit • #16
Age: 29 • Experience: 9 yrs.
Weekly Breakdown
MATCHUP
vs DAL DAL -3 O/U 51.5
OPP VS QB
9th
PROJ PTS
18.4
QB RNK
14th
2019 Stats
PAYDS
4638
RUYDS
40
TD
24
INT
16
FPTS/G
18.2
This is another game expected to be high scoring, as William Hill has the point total at 51.5. Expect a shootout between Dak Prescott and Goff, and Goff should have the chance for a strong showing in his new stadium. While Goff didn't have a great year in 2019, he closed the season with five games in a row with at least 20 Fantasy points. I'm expecting that to be his floor in Week 1 against a rebuilding Cowboys secondary.
Sleepers
Projections powered by Sportsline
NYJ N.Y. Jets • #2
Age: 34 • Experience: 14 yrs.
Weekly Breakdown
MATCHUP
@ CIN LAC -3.5 O/U 43
OPP VS QB
23rd
PROJ PTS
20
QB RNK
18th
2019 Stats
PAYDS
33
RUYDS
7
TD
1
INT
0
FPTS/G
0.9
Taylor likely won't have Mike Williams (shoulder), but he should have enough weapons to be successful in this matchup. The last two times he started in Week 1 (2018 with Cleveland and 2017 with Buffalo) he scored at least 22 Fantasy points. He's an excellent streamer.
IND Indianapolis • #17
Age: 42 • Experience: 17 yrs.
Weekly Breakdown
MATCHUP
@ JAC IND -8 O/U 45
OPP VS QB
14th
PROJ PTS
20.4
QB RNK
22nd
2019 Stats
PAYDS
4615
RUYDS
29
TD
23
INT
20
FPTS/G
17.5
Rivers usually starts off the season playing well, and he's scored at least 23 Fantasy points in three consecutive season openers. Hopefully that doesn't change with his new team, but facing the Jaguars defense should help.
NO New Orleans • #4
Age: 33 • Experience: 11 year
Weekly Breakdown
MATCHUP
@ CAR LV -3 O/U 47.5
OPP VS QB
12th
PROJ PTS
18
QB RNK
17th
2019 Stats
PAYDS
4054
RUYDS
82
TD
23
INT
8
FPTS/G
17.9
We'll see how often the Raiders are going to be road favorites, but this is a great matchup for Carr. My only concern is Josh Jacobs just dominating this game, but Carr is worth streaming in Week 1.
Sit 'Em
Projections powered by Sportsline
NYJ N.Y. Jets • #8
Age: 40 • Experience: 20 yrs.
Weekly Breakdown
MATCHUP
@ MIN MIN -2.5 O/U 45.5
OPP VS QB
11th
PROJ PTS
16.2
QB RNK
19th
YTD Stats
PAYDS
4002
RUYDS
183
TD
27
INT
4
FPTS/G
20.6
Rodgers hasn't fared well against the Vikings of late. In his past three years against Mike Zimmer's defense, Rodgers has scored 18 Fantasy points or less in four games in a row, as well as getting hurt against Minnesota in 2017. The Vikings are rebuilding in their secondary, but the pass rush could be a problem for Rodgers. In a tough matchup on the road, it's easy to fade Rodgers, and he's scored 18 Fantasy points or less in two of his past three season openers.
LAR L.A. Rams • #9
Age: 36 • Experience: 16 yrs.
Weekly Breakdown
MATCHUP
vs CHI DET -3 O/U 44.5
OPP VS QB
4th
PROJ PTS
14.8
QB RNK
13th
2019 Stats
PAYDS
2499
RUYDS
66
TD
19
INT
5
FPTS/G
25.4
Stafford didn't face the Bears in 2019 because of his back injury, but he scored a combined 24 Fantasy points in two games against Chicago in 2018. A lot has changed since then, but the Bears pass rush should be a problem for Stafford this week. I wouldn't be surprised if he scores more than 20 Fantasy points based on volume, so he's more of a bust alert than an outright sit. But I'd be hesitant to start Stafford this week in 10-team leagues and would consider other options in larger formats as well.
NYG N.Y. Giants • #8
Age: 27 • Experience: 6 yrs.
Weekly Breakdown
MATCHUP
vs PIT PIT -5.5 O/U 47.5
OPP VS QB
3rd
PROJ PTS
14.8
QB RNK
20th
2019 Stats
PAYDS
3027
RUYDS
279
TD
26
INT
12
FPTS/G
20.2
Jones should have a rough time against the Steelers this week. In their final six games in 2019, only Kyler Murray had multiple touchdowns against this defense, but Murray also had three interceptions in that outing. Pittsburgh's defense returns all of its key defensive starters, and the Giants passing game should be in trouble in Week 1. Saquon Barkley is the lone Giants player I would want to start in this matchup.
TB Tampa Bay • #6
Age: 29 • Experience: 7 yrs.
Weekly Breakdown
MATCHUP
@ BAL BAL -8 O/U 48.5
OPP VS QB
2nd
PROJ PTS
14.2
QB RNK
NR
YTD Stats
PAYDS
3827
RUYDS
141
TD
25
INT
21
FPTS/G
17.1
In four career games against the Ravens, Mayfield has three outings with 19 Fantasy points or less. You're likely starting Mayfield in two-quarterback and Superflex leagues, but that's likely the extent of it. Only three quarterbacks had multiple passing touchdowns against the Ravens last year, including Mayfield, but he passed for fewer than 200 yards and had an interception in that Week 16 matchup. I wouldn't be surprised if he has a similar performance this week.
CIN Cincinnati • #9
Age: 27 • Experience: 5 yrs.
Weekly Breakdown
MATCHUP
vs LAC LAC -3.5 O/U 43
OPP VS QB
6th
PROJ PTS
16.8
QB RNK
NR
Burrow's NFL debut could be tough, even with the Chargers missing star safety Derwin James (knee). Burrow could be seeing a lot of Joey Bosa and Melvin Ingram as the Chargers pass rush will be in his face most of the day. And the Chargers secondary should be able to frustrate A.J. Green and Tyler Boyd. It would be great to see Burrow come out and light up the Chargers at home, but I'd be hesitant to start him even in two-quarterback and Superflex leagues.
Bust Alert
Projections powered by Sportsline
TB Tampa Bay • #12
Age: 46 • Experience: 23 yrs.
Weekly Breakdown
MATCHUP
@ NO NO -3.5 O/U 48
OPP VS QB
20th
PROJ PTS
20
QB RNK
14th
YTD Stats
PAYDS
4057
RUYDS
34
TD
27
INT
8
FPTS/G
19.4
Brady was a late addition to the column because of the injury status of Mike Evans (hamstring). Even if Evans does play he clearly won't be at 100 percent, and I'm not sure Brady can have success in this matchup on the road with just Chris Godwin, Rob Gronkowski, Scott Miller and O.J. Howard. I downgraded Brady from a top-10 Fantasy quarterback to a high-end QB2, and I'm hesitant to start him with Evans banged up.